Results 91 to 100 of about 5,313 (152)

Extracellular matrix in plants and animals: hooks and locks for viruses [PDF]

, 2017
Open Access Journal; Published online: 12 Sept 2017The extracellular matrix (ECM) of animal and plants cells plays important roles in viral diseases.
Lionetti, V., Stavolone, L.
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Matrisome remodeling in the myocardium of hypertrophic cardiomyopathy; novel targets for molecular diagnostics

Frontiers in Cell and Developmental Biology
Hypertrophic cardiomyopathy (HCM) is an inherited cardiac disorder characterized by left ventricular thickening and extracellular matrix (ECM) remodeling, often manifested as increased interstitial fibrosis that impair muscle function.
Ayman M. Ibrahim, Ayman M. Ibrahim, Hasnaa A. Elfawy, Cesare M. Terracciano, Magdi Yacoub, Magdi Yacoub   +5 more
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In Situ Quantification of Surface Chemistry in Porous Collagen Biomaterials [PDF]

, 2015
Cells inside a 3D matrix (such as tissue extracellular matrix or biomaterials) sense their insoluble environment through specific binding interactions between their adhesion receptors and ligands present on the matrix surface.
Buydash, Melissa Christine, So, Peter T. C., Soller, Eric Charles, Tzeranis, Dimitrios, Yannas, Ioannis V   +4 more
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Rare loss-of-function variants in matrisome genes are enriched in Ebstein’s anomaly

HGG Advances
Summary: Ebstein’s anomaly, a rare congenital heart disease, is distinguished by the failure of embryological delamination of the tricuspid valve leaflets from the underlying primitive right ventricle myocardium. Gaining insight into the genetic basis of
Zhou Zhou, Xia Tang, Wen Chen, Qianlong Chen, Bo Ye, Angad S. Johar, Iftikhar J. Kullo, Keyue Ding   +7 more
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Emerging tumor spheroids technologies for 3D in vitro cancer modeling [PDF]

, 2018
"Article in Press, Available online 31 October 2017" ; "S0163-7258(17)30268-1"Cancer is a leading cause of mortality and morbidity worldwide. Around 90% of deaths are caused by metastasis and just 10% by primary tumor.
Alemany-Ribes, Amann, Amit, Asghar, Azarin, Banani Kundu, Barcellos-Hoff, Bartek, Bartlett, Bates, Begley, Billiet, Bremnes, Brown, Buchanan, Buchon, Byrne, Caicedo-Carvajal, Carmeliet, Carvalho, Chambers, Chaudhuri, Chwalek, Colacino, Correia, Costa, Cristini, Cuperlovic-Culf, Daphu, De Witt Hamer, Desoize, Dranoff, Dubessy, Eales, Eglen, Engel, Erapaneedi, Fang, Feng, Fennema, Friedrich, Friedrich, Fukuda, Fuller, Gill, Giuliano, Gong, Gottfried, Gu, Han, Hathaway, Hensel, Hibberd, Hickman, Hidalgo, Hoshino, Hsiao, Huang, Ivascu, Jeanray, Joana Silva-Correia, Joaquim M. Oliveira, Joyce, Khanna, Khanna, Kimlin, Kleinman, Knowlton, Koch, Kuchnio, Kunz-Schughart, Kuzet, Lecca, Lee, Lee, Li, Li, Loessner, Lohr, Lozano, Ma, Manjunathan, Martinez-Outschoorn, Mehta, Menendez, Miller, Moya, Murray, Naba, Naba, Nakazawa, Newbold, Nguyen, Nugraha, Nyga, Oliveira, Orre, Ota, Pantel, Pathak, Premnath, Qiu, Rui L. Reis, S.C. Kundu, Sabeh, Santini, Schuurman, Sethi, Shield, Silva-Correia, Silva-Correia, Simi, Siolas, Song, Stein, Tentler, Thoma, Tânia Rodrigues, Ursini-Siegel, van de Wetering, van Marion, Vinci, Vitor M. Correlo, Vonlaufen, Wang, Ward, White, Williams, Yan, Yue, Zervantonakis, Zhang, Zhang, Zhu   +133 more
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A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis [PDF]

, 2014
Extracellular matrix interactions play essential roles in normal physiology and many pathological processes. While the importance of ECM interactions in metastasis is well documented, systematic approaches to identify their roles in distinct stages of ...
Bhatia, Sangeeta N., Braga Malta, David F., Hynes, Richard O., Jacks, Tyler E., Lamar, John M., Reticker-Flynn, Nathan E., Underhill, Gregory H., Winslow, Monte M., Xu, Mary J.   +8 more
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A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis [PDF]

, 2012
Extracellular matrix interactions have essential roles in normal physiology and many pathological processes. Although the importance of extracellular matrix interactions in metastasis is well documented, systematic approaches to identify their roles in ...
A Albini, A Naba, AE Carpenter, AF Olumi, AH Bild, CJ Avraamides, CJ Flaim, CJ Flaim, CM Perou, DA Brafman, DE White, DG Beer, DR Rhodes, DS Dolberg, EL Jackson, EL Jackson, F-T Liu, G Malik, GP Gupta, H Singhal, J Hou, JA Joyce, JA Reuter, JM Lamar, JS Desgrosellier, KB Hotary, L-G Yu, LJ van 't Veer, M DuPage, MA LaBarge, MJ van de Vijver, MJC Hendrix, MM Winslow, N Nagy, P Mehlen, P Stern, PC Hoffman, PS Steeg, RO Hynes, RO Hynes, RS Bresalier*, S Paik, SS McAllister, T Oskarsson, VM Weaver, Y Mei, Y Takenaka, Y Zick   +47 more
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Matrisome and Immune Pathways Contribute to Extreme Vascular Outcomes in Williams–Beuren Syndrome

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Supravalvar aortic stenosis (SVAS) is a characteristic feature of Williams–Beuren syndrome (WBS). Its severity varies: ~20% of people with Williams–Beuren syndrome have SVAS requiring surgical intervention, whereas ~35% have no appreciable ...
Delong Liu, Charles J. Billington, Neelam Raja, Zoe C. Wong, Mark D. Levin, Wulfgang Resch, Camille Alba, Daniel N. Hupalo, Elisa Biamino, Maria Francesca Bedeschi, Maria Cristina Digilio, Gabriella Maria Squeo, Roberta Villa, Pheobe C. R. Parrish, Russell H. Knutsen, Sharon Osgood, Joy A. Freeman, Clifton L. Dalgard, Giuseppe Merla, Barbara R. Pober, Carolyn B. Mervis, Amy E. Roberts, Colleen A. Morris, Lucy R. Osborne, Beth A. Kozel   +24 more
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Targeted matrisome analysis identifies thrombospondin-2 and tenascin-C in aligned collagen stroma from invasive breast carcinoma

Scientific Reports, 2018
Increasing evidence demonstrates an important role for the extracellular matrix (ECM) in breast cancer progression. Collagen type I, a core constituent of the fibrous ECM, undergoes a significant set of changes that accompany tumor progression, termed ...
Lucas A. Tomko, Ryan C. Hill, Alexander Barrett, Joseph M. Szulczewski, Matthew W. Conklin, Kevin W. Eliceiri, Patricia J. Keely, Kirk C. Hansen, Suzanne M. Ponik   +8 more
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FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy. [PDF]

, 2019
Gene copy number alterations, tumor cell stemness, and the development of platinum chemotherapy resistance contribute to high-grade serous ovarian cancer (HGSOC) recurrence.
Anderson, Kristen, Barrie, Allison M, Bean, Lisa M, Chen, Xiao Lei, Connolly, Denise C, Cordasco, Edward A, Diaz Osterman, Carlos J, Fisch, Kathleen M, Fu, Guo, Győrffy, Balázs, Heino, Jyrki, Jean, Christine, Jiang, Shulin, Kleinschmidt, Elizabeth G, Kolev, Vihren N, Li, Jian, Mark, Adam M, McHale, Michael T, Molinolo, Alfredo, Ojalill, Marjaana, Ozmadenci, Duygu, Pachter, Jonathan A, Rappu, Pekka, Schlaepfer, David D, Stupack, Dwayne G, Sulzmaier, Florian J, Tancioni, Isabelle, Taylor, Kristin N, Uryu, Sean, Weaver, David T, Xu, Guorong   +30 more
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