Results 71 to 80 of about 4,103 (166)
Matrisome Profiling During Intervertebral Disc Development And Ageing
Scientific Reports, 2017 AbstractIntervertebral disc (IVD) degeneration is often the cause of low back pain. Degeneration occurs with age and is accompanied by extracellular matrix (ECM) depletion, culminating in nucleus pulpous (NP) extrusion and IVD destruction. The changes that occur in the disc with age have been under investigation.
Caldeira, Joana B. +6 more
openaire +3 more sources
Rare loss-of-function variants in matrisome genes are enriched in Ebstein’s anomaly
HGG AdvancesSummary: Ebstein’s anomaly, a rare congenital heart disease, is distinguished by the failure of embryological delamination of the tricuspid valve leaflets from the underlying primitive right ventricle myocardium. Gaining insight into the genetic basis of
Zhou Zhou +7 more
doaj +1 more source
Table_2_Analysis of matrisome expression patterns in murine and human dorsal root ganglia.xlsx
, 2023 The extracellular matrix (ECM) is a dynamic structure of molecules that can be divided into six different categories and are collectively called the matrisome.
Dale S. George (16842444) +13 more
core +1 more source
Frontiers in Cell and Developmental Biology, 2019 During early avian development, primordial germ cells (PGC) are highly migratory, moving from the central area pellucida of the blastoderm to the anterior extra-embryonic germinal crescent.
David J. Huss +14 more
doaj +1 more source
Pan-cancer analysis of matrisome genes.
, 2022 A) Schematic shows the steps involved in shortlisting genes from the pan-cancer TCGA dataset based on copy number (GISTIC score), expression and survival (GEPIA2 database).
Srinivas Sheshagiri Prabhu (13899216) +2 more
core +1 more source
Extracellular matrix protein composition dynamically changes during murine forelimb development
iScienceSummary: The extracellular matrix (ECM) is an integral part of multicellular organisms, connecting different cell layers and tissue types. During morphogenesis and growth, tissues undergo substantial reorganization.
Kathryn R. Jacobson +9 more
doaj +1 more source
Frontiers in Cellular NeuroscienceThe maturation of brain microvascular endothelial cells leads to the formation of a tightly sealed monolayer, known as the blood–brain barrier (BBB). The BBB damage is associated with the pathogenesis of age-related neurodegenerative diseases including ...
Yasuteru Inoue +11 more
doaj +1 more source
The extracellular matrix component perlecan/HSPG2 regulates radioresistance in prostate cancer cells
Frontiers in Cell and Developmental BiologyRadiotherapy of prostate cancer (PC) can lead to the acquisition of radioresistance through molecular mechanisms that involve, in part, cell adhesion-mediated signaling.
Ivana Samaržija +18 more
doaj +1 more source
Quantitative proteomic characterization of lung tissue in idiopathic pulmonary fibrosis
Clinical Proteomics, 2019 Background Idiopathic pulmonary fibrosis (IPF) is a progressive, eventually fatal disease. IPF is characterized by excessive accumulation of the extracellular matrix (ECM) in the alveolar parenchyma and progressive lung scarring.
Yaqiong Tian +10 more
doaj +1 more source
Molecular dynamics of the matrisome across sea anemone life history. [PDF]
ElifeAbstract The evolutionary expansion of extracellular matrix (ECM) molecules has been crucial for the establishment of cell adhesion and the transition from unicellular to multicellular life. Members of the early diverging metazoan phylum cnidaria offer an exceptionally rich perspective into the metazoan core adhesome and its original ...
Bergheim BG +7 more
europepmc +4 more sources