Analysis of cancer cell line and tissue RNA sequencing data reveals an essential and dark matrisome
Matrix Biology PlusExtracellular matrix remodeling is a hallmark of tissue development, homeostasis, and disease. The processes that mediate remodeling, and the consequences of such, are the topic of extensive focus in biomedical research.
Joshua A. Rich +5 more
doaj +1 more source
Overview of the Matrisome--An Inventory of Extracellular Matrix Constituents and Functions [PDF]
Cold Spring Harbor Perspectives in Biology, 2011 Completion of genome sequences for many organisms allows a reasonably complete definition of the complement of extracellular matrix (ECM) proteins. In mammals this "core matrisome" comprises ∼300 proteins. In addition there are large numbers of ECM-modifying enzymes, ECM-binding growth factors, and other ECM-associated proteins.
Richard O, Hynes, Alexandra, Naba
openaire +2 more sources
Data_Sheet_1_Analysis of matrisome expression patterns in murine and human dorsal root ganglia.docx
, 2023 The extracellular matrix (ECM) is a dynamic structure of molecules that can be divided into six different categories and are collectively called the matrisome.
Dale S. George (16842444) +13 more
core +1 more source
A core matrisome gene signature predicts cancer outcome [PDF]
British Journal of Cancer, 2018 Accumulating evidence implicates the tumour stroma as an important determinant of cancer progression but the protein constituents relevant for this effect are unknown. Here we utilised a bioinformatics approach to identify an extracellular matrix (ECM) gene signature overexpressed in multiple cancer types and strongly predictive of adverse outcome.Gene
Yuzhalin, A +4 more
openaire +3 more sources
Table_5_Analysis of matrisome expression patterns in murine and human dorsal root ganglia.xlsx
, 2023 The extracellular matrix (ECM) is a dynamic structure of molecules that can be divided into six different categories and are collectively called the matrisome.
Delfien Syx (221457) +27 more
core +1 more source
Lost cells, retained structure: proteomic mapping of decellularized lung matrisome across species
Materials & DesignDecellularized lung scaffolds represent a promising platform for respiratory tissue engineering, yet it remains unclear how decellularization remodels the proteome, which extracellular matrix (ECM) components are depleted or retained, and whether ...
Katarína Čimborová +12 more
doaj +1 more source
Table_1_Analysis of matrisome expression patterns in murine and human dorsal root ganglia.xlsx
, 2023 The extracellular matrix (ECM) is a dynamic structure of molecules that can be divided into six different categories and are collectively called the matrisome.
Dale S. George (16842444) +13 more
core +1 more source
Table_4_Analysis of matrisome expression patterns in murine and human dorsal root ganglia.xlsx
, 2023 The extracellular matrix (ECM) is a dynamic structure of molecules that can be divided into six different categories and are collectively called the matrisome.
Dale S. George (16842444) +13 more
core +1 more source
Matrisome protein groups as % of total protein detected.
, 2023 Matrisome protein groups as % of total protein detected.
Laetitia M. O. de Kort (11529873) +7 more
core +1 more source
, 2021 LC-MS/MS based analysis of the normal pancreas matrisome from 10 C57-Black6 animals.
Cancer Research UK Manchester Institute +1 more
core +1 more source