Results 61 to 70 of about 3,090 (127)

Proteomic analysis of decellularized mice liver and kidney extracellular matrices

Journal of Biological Engineering
Background The extracellular matrix (ECM) is a three-dimensional network of proteins that encases and supports cells within a tissue and promotes physiological and pathological cellular differentiation and functionality.
Anna-Maria Diedrich, Assal Daneshgar, Peter Tang, Oliver Klein, Annika Mohr, Olachi A. Onwuegbuchulam, Sabine von Rueden, Kerstin Menck, Annalen Bleckmann, Mazen A. Juratli, Felix Becker, Igor M. Sauer, Karl H. Hillebrandt, Andreas Pascher, Benjamin Struecker   +14 more
doaj   +1 more source

Matrisome remodeling in the myocardium of hypertrophic cardiomyopathy; novel targets for molecular diagnostics

Frontiers in Cell and Developmental Biology
Hypertrophic cardiomyopathy (HCM) is an inherited cardiac disorder characterized by left ventricular thickening and extracellular matrix (ECM) remodeling, often manifested as increased interstitial fibrosis that impair muscle function.
Ayman M. Ibrahim, Ayman M. Ibrahim, Hasnaa A. Elfawy, Cesare M. Terracciano, Magdi Yacoub, Magdi Yacoub   +5 more
doaj   +1 more source

Matrisome and Immune Pathways Contribute to Extreme Vascular Outcomes in Williams–Beuren Syndrome

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Supravalvar aortic stenosis (SVAS) is a characteristic feature of Williams–Beuren syndrome (WBS). Its severity varies: ~20% of people with Williams–Beuren syndrome have SVAS requiring surgical intervention, whereas ~35% have no appreciable ...
Delong Liu, Charles J. Billington, Neelam Raja, Zoe C. Wong, Mark D. Levin, Wulfgang Resch, Camille Alba, Daniel N. Hupalo, Elisa Biamino, Maria Francesca Bedeschi, Maria Cristina Digilio, Gabriella Maria Squeo, Roberta Villa, Pheobe C. R. Parrish, Russell H. Knutsen, Sharon Osgood, Joy A. Freeman, Clifton L. Dalgard, Giuseppe Merla, Barbara R. Pober, Carolyn B. Mervis, Amy E. Roberts, Colleen A. Morris, Lucy R. Osborne, Beth A. Kozel   +24 more
doaj   +1 more source

Targeted matrisome analysis identifies thrombospondin-2 and tenascin-C in aligned collagen stroma from invasive breast carcinoma

Scientific Reports, 2018
Increasing evidence demonstrates an important role for the extracellular matrix (ECM) in breast cancer progression. Collagen type I, a core constituent of the fibrous ECM, undergoes a significant set of changes that accompany tumor progression, termed ...
Lucas A. Tomko, Ryan C. Hill, Alexander Barrett, Joseph M. Szulczewski, Matthew W. Conklin, Kevin W. Eliceiri, Patricia J. Keely, Kirk C. Hansen, Suzanne M. Ponik   +8 more
doaj   +1 more source

Editorial: Proteoglycans in the Tumor Microenvironment

Frontiers in Oncology, 2022
Jlenia Brunetti, Manuela Viola, Federico Corti   +2 more
doaj   +1 more source

Multiple aspects of matrix stiffness in cancer progression

Frontiers in Oncology
The biophysical and biomechanical properties of the extracellular matrix (ECM) are crucial in the processes of cell differentiation and proliferation.
Alessandro Mancini, Alessandro Mancini, Maria Teresa Gentile, Francesca Pentimalli, Salvatore Cortellino, Salvatore Cortellino, Salvatore Cortellino, Michele Grieco, Antonio Giordano, Antonio Giordano   +9 more
doaj   +1 more source

Identification of Pancreatic Ductal Adenocarcinoma Extracellular Matrix Signatures from In-Depth Proteomic Profiling that Correlate with Lymphocyte Infiltration. [PDF]

Cancer Res Commun
Considine JM, Pally D, O'Brien SA, Egan JN, Feng D, Pignatelli J, Kashyap A, Sharma NS, Naba A.   +8 more
europepmc   +1 more source

Pathological extracellular matrix changes in decellularized normal appearing gray matter and subpial multiple sclerosis lesions. [PDF]

iScience
de Jong JM, Wolters JC, Wijering MHC, de Vries J, Kooistra SM, Eggen BJL, Baron W.   +6 more
europepmc   +1 more source

An Extracellular Matrix Aging Clock Based on Circulating Matrisome Proteins Predicts Biological Aging and Disease. [PDF]

Aging Cell
Coenen L, Molière A, Lehallier B, Middeldorp J, Ewald CY.   +4 more
europepmc   +1 more source

Proteomic evaluation and comparison of native and decellularized human saphenous vein extracellular matrices. [PDF]

Front Bioeng Biotechnol
Niemi EM, Nyman TA, Attramadal H, Hoel H, Rosales A, Hisdal J, Scholz H.   +6 more
europepmc   +1 more source