Results 41 to 50 of about 4,103 (166)

Novel prognostic matrisome-related gene signature of head and neck squamous cell carcinoma

open access: yesFrontiers in Cell and Developmental Biology, 2022
Background: Head and neck squamous cell carcinoma (HNSCC) is a common malignancy of the mucosal epithelium of the oral cavity, pharynx, and larynx.
Chao Huang   +13 more
doaj   +1 more source

Mutations in a set of ancient matrisomal glycoprotein genes across neoplasia predispose to disruption of morphogenetic transduction

open access: yesComputational and Systems Oncology, 2022
Misexpression and remodeling of the extracellular matrix is a canonical hallmark of cancer, although the extent of cancer‐associated aberrations in the genes coding for extracellular matrix (ECM) proteins and the consequences thereof are not well ...
Jimpi Langthasa   +4 more
doaj   +1 more source

The in-silico characterization of the Caenorhabditis elegans matrisome and proposal of a novel collagen classification

open access: yesMatrix Biology Plus, 2019
Proteins are the building blocks of life. While proteins and their localization within cells and sub-cellular compartments are well defined, the proteins predicted to be secreted to form the extracellular matrix - or matrisome - remain elusive in the ...
Alina C. Teuscher   +6 more
doaj   +1 more source

Deciphering the Kidney Matrisome: Identification and Quantification of Renal Extracellular Matrix Proteins in Healthy Mice

open access: yes, 2023
Precise characterization of a tissue’s extracellular matrix (ECM) protein composition (matrisome) is essential for biomedicine. However, ECM protein extraction that requires organ-specific optimization is still a major limiting factor in matrisome ...
Guller, A ; https://orcid.org/   +13 more
core   +1 more source

Proteomics, Glycomics, and Glycoproteomics of Matrisome Molecules

open access: yesMolecular & Cellular Proteomics, 2019
The most straightforward applications of proteomics database searching involve intracellular proteins. Although intracellular gene products number in the thousands, their well-defined post-translational modifications (PTMs) makes database searching practical.
Rekha Raghunathan   +3 more
openaire   +2 more sources

Targeting Versican as a Potential Immunotherapeutic Strategy in the Treatment of Cancer

open access: yesFrontiers in Oncology, 2021
A growing body of literature links events associated with the progression and severity of immunity and inflammatory disease with the composition of the tissue extracellular matrix as defined by the matrisome.
Priyanka Hirani   +4 more
doaj   +1 more source

Comprehensive Profiling of Early Neoplastic Gastric Microenvironment Modifications and Biodynamics in Impaired BMP-Signaling FoxL1+-Telocytes

open access: yesBiomedicines, 2022
FoxL1+telocytes (TCFoxL1+) are novel gastrointestinal subepithelial cells that form a communication axis between the mesenchyme and epithelium. TCFoxL1+ are strategically positioned to be key contributors to the microenvironment through production and ...
Alain B. Alfonso   +6 more
doaj   +1 more source

Longevity-Promoting Pathways and Transcription Factors Respond to and Control Extracellular Matrix Dynamics During Aging and Disease

open access: yesFrontiers in Aging, 2022
Aging is one of the largest risk factors for cancer, type 2 diabetes, osteoarthritis, cardiovascular diseases, and other age-related pathologies. Here, we give a detailed description of the interplay of chronic age-related pathologies with the remodeling
Tinka Vidović, Collin Y. Ewald
doaj   +1 more source

Table_3_Analysis of matrisome expression patterns in murine and human dorsal root ganglia.xlsx

open access: yes, 2023
The extracellular matrix (ECM) is a dynamic structure of molecules that can be divided into six different categories and are collectively called the matrisome.
Dale S. George (16842444)   +13 more
core   +1 more source

Matrisome comparison between species.

open access: yes, 2018
Comparison of the matrisome proteins detected in different decellualrized lung tissues showed overlap of the most abundant lung proteins like collagen I, and IV, fibronectin, fibrillin, and laminins. Venn’s diagram shows the overlap of proteins allocated
Franziska E. Uhl (5459576)   +13 more
core   +1 more source

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