Results 101 to 110 of about 5,938 (234)
Extracellular matrix protein composition dynamically changes during murine forelimb development
iScienceSummary: The extracellular matrix (ECM) is an integral part of multicellular organisms, connecting different cell layers and tissue types. During morphogenesis and growth, tissues undergo substantial reorganization.
Kathryn R. Jacobson +9 more
doaj +1 more source
Quantitative proteomic characterization of lung tissue in idiopathic pulmonary fibrosis
Clinical Proteomics, 2019 Background Idiopathic pulmonary fibrosis (IPF) is a progressive, eventually fatal disease. IPF is characterized by excessive accumulation of the extracellular matrix (ECM) in the alveolar parenchyma and progressive lung scarring.
Yaqiong Tian +10 more
doaj +1 more source
Aging Cell, Volume 24, Issue 11, November 2025.Choline‐protected genes correlated with clinical dementia rating, inflammation, and tauopathy in human AD samples, suggesting that adequate choline intake could be a preventive strategy for Alzheimer's disease (AD). ABSTRACT Alzheimer's disease (AD)—the leading cause of dementia—has no cure, inadequate treatment options, and a limited understanding of ...
Thomas A. Bellio +8 more
wiley +1 more source
Differential regulation of extracellular matrix protein expression in carcinoma-associated fibroblasts by TGF-β1 regulates cancer cell spreading but not adhesion [PDF]
, 2014 Cancer progression is characterized by a complex reciprocity between neoplastic epithelium and adjacent stromal cells. In ductal carcinoma in situ (DCIS) of the breast, both reduced stromal decorin expression and myxoid stroma are correlated with ...
Bracke, Marc +11 more
core +3 more sources
Sex, age, tissue, and disease patterns of matrisome expression in GTEx transcriptome data [PDF]
, 2021 Tim O. Nieuwenhuis +3 more
openalex +1 more source
British Journal of Pharmacology, Volume 182, Issue 22, Page 5647-5669, November 2025.Background and Purpose Chronic liver disease and hepatic fibrosis constitute a threat to global health. Clinical translation of preclinical research has been limited, highlighting an urgent need for novel treatments. Cyclophilin inhibitors have shown beneficial effects in liver disease; however, the underlying mechanism of action and the effect across ...
Una Rastovic +24 more
wiley +1 more source
Hepatology Research, Volume 55, Issue 11, Page 1425-1436, November 2025.ABSTRACT Chronic liver diseases (CLD) arising from various etiologies including viral hepatitis, excessive alcohol intake, alcoholic associated liver disease (ALD) and metabolic dysfunction‐associated steatotic liver disease (MASLD), are associated with persistent hepatic injury ultimately resulting in fibrosis.
Fidaa Bouezzedine +2 more
wiley +1 more source
Data from NELL1 Regulates the Matrisome to Promote Osteosarcoma Progression
, 2023 Qizhi Qin +8 more
openalex +2 more sources
The extracellular matrix phenome across species
Matrix Biology Plus, 2020 Extracellular matrices are essential for cellular and organismal function. Recent genome-wide and phenome-wide association studies started to reveal a broad spectrum of phenotypes associated with genetic variants.
Cyril Statzer, Collin Y. Ewald
doaj +1 more source
Transcriptional profiling of the ductus arteriosus: Comparison of rodent microarrays and human RNA sequencing [PDF]
, 2018 DA closure is crucial for the transition from fetal to neonatal life. This closure is supported by changes to the DA’s signaling and structural properties that distinguish it from neighboring vessels.
Clyman, Ronald I. +8 more
core +1 more source