Results 101 to 110 of about 5,313 (152)

Modeling Progressive Fibrosis with Pluripotent Stem Cells Identifies an Anti-fibrotic Small Molecule. [PDF]

, 2019
Progressive organ fibrosis accounts for one-third of all deaths worldwide, yet preclinical models that mimic the complex, progressive nature of the disease are lacking, and hence, there are no curative therapies. Progressive fibrosis across organs shares
Ahadome, Sarah D, Aros, Cody J, Bhatt, Kush V, Chung, Katherine, Clark, Amander T, Damoiseaux, Robert, Darmawan, Kelly F, Durra, Abdo, Gomperts, Brigitte N, Graeber, Thomas G, Karumbayaram, Saravanan, Manze, Chase C, Mehrabi, Mehrsa, Minasyan, Aspram, Paul, Manash K, Rickabaugh, Tammy M, Sandlin, Jenna M, Shia, David W, Vijayaraj, Preethi, Wallace, W Dean, Wilkinson, Dan C, Yan, Weihong   +21 more
core   +1 more source

Multiple aspects of matrix stiffness in cancer progression

Frontiers in Oncology
The biophysical and biomechanical properties of the extracellular matrix (ECM) are crucial in the processes of cell differentiation and proliferation.
Alessandro Mancini, Alessandro Mancini, Maria Teresa Gentile, Francesca Pentimalli, Salvatore Cortellino, Salvatore Cortellino, Salvatore Cortellino, Michele Grieco, Antonio Giordano, Antonio Giordano   +9 more
doaj   +1 more source

Dynamics of compartment-specific proteomic landscapes of hepatotoxic and cholestatic models of liver fibrosis

eLife
Accumulation of extracellular matrix (ECM) in liver fibrosis is associated with changes in protein abundance and composition depending upon etiology of the underlying liver disease.
Marketa Jirouskova, Karel Harant, Pavel Cejnar, Srikant Ojha, Katerina Korelova, Lenka Sarnova, Eva Sticova, Christoph H Mayr, Herbert B Schiller, Martin Gregor   +9 more
doaj   +1 more source

Meta-analysis of differential gene expression in lower motor neurons isolated by laser capture microdissection from post-mortem ALS spinal cords

Frontiers in Genetics
IntroductionALS is a fatal neurodegenerative disease for which underlying mechanisms are incompletely understood. The motor neuron is a central player in ALS pathogenesis but different transcriptome signatures have been derived from bulk analysis of post-
William R. Swindell
doaj   +1 more source

Editorial: Proteoglycans in the Tumor Microenvironment

Frontiers in Oncology, 2022
Jlenia Brunetti, Manuela Viola, Federico Corti   +2 more
doaj   +1 more source

Role of matrix metalloproteinases in the pathogenesis of idiopathic pulmonary fibrosis [PDF]

, 2016

core   +1 more source

Brain region‐specific accumulation of amyloidosis‐associated proteins in postmortem brain tissues of Alzheimer's disease patients [PDF]

Alzheimers Dement
Tsering W, Phillips J, Villareal J, Prokop S.   +3 more
europepmc   +2 more sources

Comparative proteomic analysis of the ECM composition of the human omentum and mesentery, the main sites of ovarian cancer metastasis. [PDF]

iScience
Considine JM, Gomez C, Pally D, Yang N, Taha IN, Sorenson J, Brooks EG, Kreeger PK, Naba A.   +8 more
europepmc   +1 more source

The islet-resident macrophage is in an inflammatory state and senses microbial products in blood [PDF]

, 2017
Aggarwal, Amit, Amit, Anders, Andrade, Banaei-Bouchareb, Boris Calderon, Buxadé, Calderon, Calderon, Calderon, Carrero, Castellino, Chee, Chen, Chevrier, Christen, del Rey, Diana, Diana, Dinarello, Dobin, Droop, Dror, Dufour, Emil R. Unanue, Ewald, Ferris, Foster, Fridovich, García, Gautier, Gilchrist, Greeley, Griffith, Haldar, Harrow, Heng, Javier A. Carrero, Johnson, Kaikkonen, Kanehisa, Kawai, Kim, Koblansky, Kotas, Kurth, Kägi, Lavin, Litvak, Love, Mandrup-Poulsen, Markle, Matloubian, Maxim N. Artyomov, Melli, Mi, Mi, Miller, Mootha, Moratz, Oldenburg, Pakala, Park, Pasparakis, Pavel N. Zakharov, Reddy, Reif, Ritchie, Rütti, Schott, Smyth, Stephen T. Ferris, Subramanian, Suri, Tai, Terauchi, Thomas, Vomund, Wen, Wood, Wu, Xiaoxiao Wan, Yamada, Yang, Yosef, Yosef, Yurkovetskiy, Zhao   +88 more
core   +2 more sources

Comparison of different decellularization protocols for porcine centrum tendineum diaphragmatis and diaphragmatic muscle - a base for effective recellularization. [PDF]

J Biol Eng
Gaag BF, Tang P, Klein O, Moosburner S, Böhm AK, Lohmann T, Wieland JK, Contes V, Zhou Y, Keshi E, Haderer L, Metzler E, Schöwel-Wolf V, Spuler S, Rückert JC, Pratschke J, Sauer IM, Andreas MN, Hillebrandt KH.   +18 more
europepmc   +1 more source