Results 141 to 150 of about 5,603 (226)

Multiple aspects of matrix stiffness in cancer progression

Frontiers in Oncology
The biophysical and biomechanical properties of the extracellular matrix (ECM) are crucial in the processes of cell differentiation and proliferation.
Alessandro Mancini, Alessandro Mancini, Maria Teresa Gentile, Francesca Pentimalli, Salvatore Cortellino, Salvatore Cortellino, Salvatore Cortellino, Michele Grieco, Antonio Giordano, Antonio Giordano   +9 more
doaj   +1 more source

SYSTEMS LEVEL IDENTIFICATION OF A MATRISOME-ASSOCIATED MACROPHAGE POLARIZATION STATE IN MULTI-ORGAN FIBROSIS

, 2023
John F. Ouyang, Enrico Petretto, Jacques Behmoaras   +2 more
openalex   +1 more source

The Burden of Post-Translational Modification (PTM)—Disrupting Mutations in the Tumor Matrisome [PDF]

, 2021
Elisa Holstein, Annalena Dittmann, Anni Kääriäinen, Vilma Pesola, Jarkko Koivunen, Taina Pihlajaniemi, Alexandra Naba, Valerio Izzi   +7 more
openalex   +1 more source

Comprehensive Matrisome Profiling of Human Adipose Tissue for Soft Tissue Reconstruction [PDF]

, 2023
Gretel S. Major, Jeremy Simcock, Abhishek Kumar, Torsten Kleffmann, Tim B. F. Woodfield, Khoon S. Lim   +5 more
openalex   +1 more source

The role of the synovial microenvironment in Rheumatoid Arthritis [PDF]

Rheumatoid Arthritis (RA) remains plagued by poor treatment responses and a lack of curative solutions despite a dense armamentarium. A deeper investigation into the tissue biology of the RA synovium, including its cells but also the remodelled ...
Richard, Jean-Baptiste
core   +2 more sources

Figure S4 from Cancer Cell–Derived Matrisome Proteins Promote Metastasis in Pancreatic Ductal Adenocarcinoma [PDF]

, 2023
Chenxi Tian, Daniel Öhlund, Steffen Rickelt, Tommy Lidström, Ying Huang, Liang Hao, Renee T. Zhao, Oskar Franklin, Sangeeta N. Bhatia, David A. Tuveson, Richard O. Hynes   +10 more
openalex   +1 more source

Meta-analysis of differential gene expression in lower motor neurons isolated by laser capture microdissection from post-mortem ALS spinal cords

Frontiers in Genetics
IntroductionALS is a fatal neurodegenerative disease for which underlying mechanisms are incompletely understood. The motor neuron is a central player in ALS pathogenesis but different transcriptome signatures have been derived from bulk analysis of post-
William R. Swindell
doaj   +1 more source

Targets in the Tumour Matrisome to Promote Cancer Therapy Response

Cancers
The extracellular matrix (ECM) is composed of complex fibrillar proteins, proteoglycans, and macromolecules, generated by stromal, immune, and cancer cells. The components and organisation of the matrix evolves as tumours progress to invasive disease and metastasis.
Siti Munira Abd Jalil, Jack C. Henry, Angus J. M. Cameron   +2 more
openaire   +2 more sources

Editorial: Proteoglycans in the Tumor Microenvironment

Frontiers in Oncology, 2022
Jlenia Brunetti, Manuela Viola, Federico Corti   +2 more
doaj   +1 more source

Mesenchyme-derived vertebrate lonesome kinase controls lung organogenesis by altering the matrisome [PDF]

, 2023
Salome M. Brütsch, Elizabeta Madzharova, Sophia Pantasis, Till Wüstemann, Selina Gurri, Heiko Steenbock, Amiq Gazdhar, Gisela Kuhn, Peter Angel, Saverio Bellusci, Jürgen Brinckmann, Ulrich auf dem Keller, Sabine Werner, Mattia R. Bordoli   +13 more
openalex   +1 more source