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The cancer matrisome: From comprehensive characterization to biomarker discovery

Seminars in Cell & Developmental Biology, 2019
Tumor progression and dissemination critically depend on support from the tumor microenvironment, the ensemble of cellular and acellular components surrounding and interacting with tumor cells. The extracellular matrix (ECM), the complex scaffolding of hundreds of proteins organizing cells in tissues, is a major component of the tumor microenvironment.
Alexandra M. Socovich, Alexandra Naba
openaire   +2 more sources

Tenascin-C in the matrisome of neural stem and progenitor cells

Molecular and Cellular Neuroscience, 2017
The extracellular matrix consists of glycoproteins, proteoglycans and complex glycan structures that form the matrisome. Increasing evidence points to important functional roles of the ECM during development, plasticity and regeneration of the CNS. In particular, the ECM is an important constituent of the molecular microenvironment of the neural stem ...
Andreas, Faissner   +2 more
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Matrisome Expression in the Dorsal Root Ganglion

The Journal of Pain, 2022
Robin Vroman   +6 more
openaire   +1 more source

Templates for Neural Dynamics in the Striatum: Striosomes and Matrisomes

2010
The striatum appears to be a relatively simple forebrain region compared to the overlying neocortex, with its horizontal layers and vertical columns. In fact, the striatum in mammals has a sophisticated architecture of its own. This large subcortical region is now suspected of having a major influence on how the neocortex carries out its own functions ...
openaire   +1 more source

The Burden of Post-Translational Modification (PTM)—Disrupting Mutations in the Tumor Matrisome

Cancers, 2021
Jarkko Koivunen   +2 more
exaly  

Machine Learning Identifies Robust Matrisome Markers and Regulatory Mechanisms in Cancer

International Journal of Molecular Sciences, 2020
Jarkko Koivunen   +2 more
exaly  

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