Results 101 to 110 of about 3,348,378 (252)
Association of the Matrix Attachment Region Recognition Signature with coding regions in
, 2007 Background Matrix attachment regions (MAR) are the sites on genomic DNA that interact with the nuclear matrix. There is increasing evidence for the involvement of MAR in regulation of gene expression.
Blaxter Mark +6 more
core +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
JGR-NMF: joint graph-regularized non-negative matrix factorization for spatial domain identification [PDF]
PeerJThe spatial transcriptomics technique provides an unprecedented perspective for analyzing the distribution patterns of cells within tissues and their functional tissue structures.
Juan Liang +4 more
doaj +2 more sources
Matrix Interpretations on Polyhedral Domains.
, 2015 We refine matrix interpretations for proving termination and complexity bounds of term rewrite systems we restricting them to domains that satisfy a system of linear inequalities. Admissibility of such a restriction is shown by certificates whose validity can be expressed as a constraint program.
openaire +3 more sources
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Almost Sequence Spaces Derived by the Domain of the Matrix
Abstract and Applied Analysis, 2013 By using , we introduce the sequence spaces , , and of normed space and -space and prove that , and are linearly isomorphic to the sequence spaces , , and , respectively.
Ali Karaisa, Ümıt Karabıyık
doaj +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
The next step in the strategy–as–practice evolution: A comparative typology matrix
Acta Commercii, 2016 Orientation: In 2009, Strategy-as-Practice (S-as-P) research, as a subfield of strategy research, was grouped into nine different domains, and researchers were advised to frame their research within these domains.
Karen Stander, Marius Pretorius
doaj +1 more source