Results 101 to 110 of about 3,837,712 (252)
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Maritime Domain Protections Research Group (archived) [PDF]
, 2013 The Maritime Domain Protection Research Group (formerly known as the Maritime Domain Protection Task Force) was formed to investigate issues surrounding protection of the United States, its vessels, and citizens from terrorist threats originating in the ...
core +2 more sources
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Functional studies of matrix metalloproteinases (MMP14, 15, 16) in animal and cell culture models [PDF]
, 2003 Li H. Functional studies of matrix metalloproteinases (MMP14, 15, 16) in animal and cell culture models. Bielefeld (Germany): Bielefeld University; 2003.It has been known, MT1-, 2-, 3-, 5-MMP have a transmembrane (TM) domain and MT4-, 6-MMP contain a GPI
Li, Hongbin
core
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source
A class of alternate strip-based domain decomposition methods for elliptic partial differential Equations [PDF]
, 2005 The domain decomposition strategies proposed in this thesis are efficient preconditioning techniques with good parallelism properties for the discrete systems which arise from the finite element approximation of symmetric elliptic boundary value problems
Mihai, Loredana Angela
core
Multi Domain Matrix (MDM) of the Vertical Hydrogenerator [PDF]
, 2019 Purpose of this work was to show connections between vertical hydrogenerator design parameters. Authors made DSM (Design Structure Matrix), to show design parameters dependencies, first matrix size was reduced and it does not consist of all design ...
Stamać, Lucijan +2 more
core +1 more source
Generalized equivalence of matrices over Prüfer domains
International Journal of Mathematics and Mathematical Sciences, 1991 Two m×n matrices A,B over a commutative ring R are equivalent in case there are invertible matrices P, Q over R with B=PAQ. While any m×n matrix over a principle ideal domain can be diagonalized, the same is not true for Dedekind domains.
Frank DeMeyer, Hainya Kakakhail
doaj +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
p160/SRC/NCoA coactivators form complexes via specific interaction of their PAS-B domain with the CID/AD1 domain [PDF]
, 2008 Transcriptional activation involves the ordered recruitment of coactivators via direct interactions between distinct binding domains and recognition motifs.
Coudevylle, N. +12 more
core +1 more source