Results 91 to 100 of about 3,837,712 (252)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

JGR-NMF: joint graph-regularized non-negative matrix factorization for spatial domain identification [PDF]

open access: yesPeerJ
The spatial transcriptomics technique provides an unprecedented perspective for analyzing the distribution patterns of cells within tissues and their functional tissue structures.
Juan Liang   +4 more
doaj   +2 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Matrix Interpretations on Polyhedral Domains.

open access: yes, 2015
We refine matrix interpretations for proving termination and complexity bounds of term rewrite systems we restricting them to domains that satisfy a system of linear inequalities. Admissibility of such a restriction is shown by certificates whose validity can be expressed as a constraint program.
openaire   +3 more sources

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Knowledge-aware Neural Collective Matrix Factorization for Cross-domain Recommendation

open access: yes, 2022
Cross-domain recommendation (CDR) can help customers find more satisfying items in different domains. Existing CDR models mainly use common users or mapping functions as bridges between domains but have very limited exploration in fully utilizing extra ...
Ni, Jianmo   +4 more
core  

Application of joint domain localised matrix CFAR detector for HFSWR

open access: yesThe Journal of Engineering, 2019
Target detection is one of the most important parts of high-frequency surface wave radar (HFSWR) signal processing, to find targets in noise or clutter and obtain targets’ information.
Lei Ye   +3 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

The Complex Domain Matrix of Ditransitive Constructions [PDF]

open access: yes, 2010
This study focuses on the semantics of ditransitive constructions. Its main aim is to show that the semantics of this type of construction is made up of elements belonging to different conceptual domains. In order to fully analyze the complexity inherent
Huelva-Unternbaumen, Enrique
core   +1 more source

Almost Sequence Spaces Derived by the Domain of the Matrix

open access: yesAbstract and Applied Analysis, 2013
By using , we introduce the sequence spaces , , and of normed space and -space and prove that , and are linearly isomorphic to the sequence spaces , , and , respectively.
Ali Karaisa, Ümıt Karabıyık
doaj   +1 more source

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