Results 91 to 100 of about 3,348,378 (252)

Compiling a domain specific language for dynamic programming [PDF]

open access: yes, 2006
Steffen P. Compiling a domain specific language for dynamic programming.
Steffen, Peter
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Generalized equivalence of matrices over Prüfer domains

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1991
Two m×n matrices A,B over a commutative ring R are equivalent in case there are invertible matrices P, Q over R with B=PAQ. While any m×n matrix over a principle ideal domain can be diagonalized, the same is not true for Dedekind domains.
Frank DeMeyer, Hainya Kakakhail
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Norm of Operators on the Generalized Cesàro Matrix Domain

open access: yesCommunications in Advanced Mathematical Sciences, 2020
Roopaei in [13] has introduced some factorization for the infinite Hilbert matrix and the Cesàro matrix of order n based on the generalized Cesàro matrix.
Maryam Sinaei
doaj  

Application of joint domain localised matrix CFAR detector for HFSWR

open access: yesThe Journal of Engineering, 2019
Target detection is one of the most important parts of high-frequency surface wave radar (HFSWR) signal processing, to find targets in noise or clutter and obtain targets’ information.
Lei Ye   +3 more
doaj   +1 more source

Public Domain

open access: yes, 2021
Learning Objectives: Describe the public domain’s scope and relationship with copyright; Recognize the three categories of works in the public domain; Identify public domain works; Contribute your own works to the public ...
McNally, Michael B., Wakaruk, Amanda
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Matrix metalloproteinases: Fold and function of their catalytic domains

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2010
Matrix metalloproteinases (MMPs) are zinc-dependent protein and peptide hydrolases. They have been almost exclusively studied in vertebrates and 23 paralogs are present in humans. They are widely involved in metabolism regulation through both extensive protein degradation and selective peptide-bond hydrolysis.
Tallant, Cynthia   +2 more
openaire   +3 more sources

Matrix

open access: yes, 2018
Matrix of 53 dental characters and 13 paromomyid ...
Sergi López-Torres (7061078)   +1 more
core   +1 more source

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