Results 111 to 120 of about 253,196 (234)

Encapsulation nanoarchitectonics of glabridin with sophorolipid micelles for addressing biofilm hazards via extracellular polymeric substance permeation and srtA gene suppression

Ecotoxicology and Environmental Safety
Background: Biofilm, a common drug-resistant phenotype of Staphylococcus aureus (S. aureus), demonstrates significant drug resistance and recurrence due to its extracellular polymeric substance (EPS) barrier and subsequent bacterial migration.
Shiyu Lin, Xiaojuan Li, Wei Zhang, Gang Shu, Haohuan Li, Funeng Xu, Juchun Lin, Guangneng Peng, Li Zhang, Hualin Fu   +9 more
doaj   +1 more source

Identification of an osteocalcin isoform in fish with a large acidic prodomain [PDF]

, 2014
Osteocalcin is a small, secreted bone protein whose gene consists of four exons. In the course of analyzing the structure of fish osteocalcin genes, we recently found that the spotted green pufferfish has two possible exon 2 structures, one of 15 bp and ...
Amores, Boskey, Chomczynski, Christensen, Crooks, Ducy, Engelke, Frazão, Gorski, Gundberg, Hauschka, Hauschka, He, Hosoda, Hunter, Huq, Jaillon, Kumar, Laizé, Nakayama, Nielsen, Nishimoto, Notredame, Patthy, Poser, Price, Sommer, Stothard, Taylor, Thompson, Woods   +30 more
core   +1 more source

Recent advances of emergent extraction technologies to enhance bioactive compounds extraction of microalgae—An overview towards application in cosmetics

International Journal of Cosmetic Science, EarlyView.
Microalgae extracts show immense potential in cosmetics for their bioactivities; emerging extraction techniques enhance bioactive compound yield from microalgae. Abstract Microalgae have attracted significant interest in numerous sectors, particularly in the cosmetic industries, owing to their rich composition of bioactive compounds. This paper aims to
Alireza Mousakhani Ganjeh, Lucília da P. da Silva, Carlos A. Pinto, Rosário Martins, Alexandra P. Marques, Jorge A. Saraiva   +5 more
wiley   +1 more source

A high-throughput mass spectrometric assay for discovery of human lipoxygenase inhibitors and allosteric effectors. [PDF]

, 2015
Lipoxygenases (LOXs) regulate inflammation through the production of a variety of molecules whose specific downstream effects are not entirely understood due to the complexity of the inflammation pathway.
Holman, Theodore R, Jameson, J Brian, Kenyon, Victor   +2 more
core   +1 more source

Beyond Starch: Towards a Scalable Potato Platform for Molecular Farming

Plant Biotechnology Journal, EarlyView.
ABSTRACT Thirty‐five years after the first recombinant protein was produced in potato and 30 years after clinical trials of edible vaccines from its tubers, the crop is being reconsidered as a molecular farming chassis. Potatoes can accumulate recombinant proteins in tubers, enabling long‐term storage and simplified logistics.
Izabela Anna Chincinska, Dorota Sołtys‐Kalina, Audrey Y.‐H. Teh   +2 more
wiley   +1 more source

Molecular pathophysiology of chronic kidney disease–mineral and bone disorder: Focus on the fibroblast growth factor 23–Klotho axis and bone turnover dynamics

Experimental Physiology, EarlyView.
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu, Laras Pratiwi, Henry Sutanto, Djoko Santoso, Decsa Medika Hertanto   +4 more
wiley   +1 more source

Effect of vitamin K1 supplementation on matrix Gla protein level and vascular calcification in hemodialysis patients

The Egyptian Journal of Internal Medicine, 2017
Background Matrix Gla protein (MGP) is a potent calcification inhibitor of the arterial wall. Its activity depends on vitamin K-dependent γ-carboxyglutamate.
Ahmed Alla Eldin Ahmed Saad, Eglal Mohammed Kenawy, Ahmed Mohammed Elashakr, Hesham Hamdy Amin, Ahmed Abo Elfatoh Eldali, Waleed Saber Mohammed   +5 more
doaj   +1 more source

High vitamin K status is prospectively associated with decreased left ventricular mass in women: the Hoorn Study

Nutrition Journal, 2021
Background Vitamin K is associated with reduced cardiovascular disease risk such as heart failure, possibly by carboxylation of matrix-gla protein (MGP), a potent inhibitor of vascular calcification.
Joline W. J. Beulens, Elisa Dal Canto, Coen D. A. Stehouwer, Roger J. M. W. Rennenberg, Petra J. M. Elders, Adriana Johanne van Ballegooijen   +5 more
doaj   +1 more source

The relationships between vitamin K and cognition: a review of current evidence [PDF]

, 2019
Vitamin K is a fat-soluble nutrient discovered in 1935 and its role in blood coagulation has been thoroughly explored. In recent years, studies conducted in vitro and on animals highlighted vitamin K involvement in brain cells development and survival ...
Alisi, Ludovico, Cafolla, Arturo, Cao, Roberta, Caramia, Francesca, Cartocci, Gaia, De Angelis, Cristina, Fiorelli, Marco, Librando, Aloisa   +7 more
core   +2 more sources

Conservation of Neuron‐Astrocyte Correlated Activity in Developing Sensory Pathways

Glia, Volume 74, Issue 5, May 2026.
Astrocytes and neurons in the superior colliculus exhibit spatiotemporal correlated activity before eye opening. Each neuronal wave is followed by a calcium wave in astrocytes. Spillover of glutamate activates mGluR5 and mGluR3 in astrocytes. ABSTRACT Neurons in developing sensory organs exhibit prolonged burst firing before the onset of sensory ...
Vered Kellner, Patrick Parker, Dongeun Heo, Xuelong Mi, Mikhail Coen, Guoqiang Yu, Gesine Saher, Loyal A. Goff, Dwight E. Bergles   +8 more
wiley   +1 more source