Results 121 to 130 of about 253,196 (234)

Missense mutation of VKORC1 leads to medial arterial calcification in rats

Scientific Reports, 2018
Vitamin K plays a crucial role in the regulation of vascular calcifications by allowing activation of matrix Gla protein. The dietary requirement for vitamin K is low because of an efficient recycling of vitamin K by vitamin K epoxide reductase (VKORC1).
Arnaud Michaux, Benjamin Matagrin, Jean-Valéry Debaux, Leon J. Schurgers, Etienne Benoit, Virginie Lattard   +5 more
doaj   +1 more source

Calcific uraemic arteriolopathy - A mini-review [PDF]

, 2016
Calcific Uraemic Arteriolopathy (CUA) or calciphylaxis, is a thrombotic disorder of skin and subcutaneous tissue which typically presents with painful purpuric nodules that may progress to necrotic ulcers, and is a severe, life-threatening condition. CUA
Agapii, Rodica, Fragoso, Andr?, Jerónimo, Teresa, Mendes, Filipa, Neves, Pedro L, Pimentel, Ana, Rocha, Sofia Couto, Silva, Ana   +7 more
core  

Effects of Thyroxine Exposure on Osteogenesis in Mouse Calvarial Pre-Osteoblasts [PDF]

, 2013
The incidence of craniosynostosis is one in every 1,800-2500 births. The gene-environment model proposes that if a genetic predisposition is coupled with environmental exposures, the effects can be multiplicative resulting in severely abnormal phenotypes.
A Mansukhani, AK Coussens, BD Stamper, BK Huang, BU Ang, C Owen, C Yao, CB Harvey, CH Shackleton, CW Li, D Gomez, D Johnson, DC Robinson, DP Rice, DT Gault, G Radetti, G Ramajayam, GA Brent, GM Morriss-Kay, GR Williams, H Kohara, H Miraoui, HJ Kim, J Connerney, J Esparza, J Zumbrunn, JA Greenwald, Jack C. Yu, James J. Cray, JH Bassett, JH Oh, JL Penfold, JM Britto, JQ Feng, JS Morey, K Kasono, KA Kapp-Simon, Kameron Khaksarfard, KM Lee, M Bodo, M Menking, M Segni, MH Sheng, MM Cohen Jr, Mohammed Elsalanty, PJ Marie, R Rice, S Akita, S Wadhwa, S Weiss, SA Boyadjiev, SA Rasmussen, Seth M. Weinberg, W Arlt, W Riggs Jr, WM Chadduck, Xing-Ming Shi, Y Xiong, Z von Marschall   +58 more
core   +2 more sources

Diversification with minor oilseeds: Effects on system productivity and nitrogen use efficiency in semi‐arid Canadian prairies

Agronomy Journal, Volume 118, Issue 2, March/April 2026.
Abstract Diversified cropping systems in the semi‐arid Canadian prairies comprise major cereal, oilseed, and pulse crops. Further diversification with minor oilseeds, such as oriental (Brassica juncea), industrial (Brassica carinata L.), and yellow (Sinapis alba L.) mustard, camelina [Camelina sativa (L.) Crantz], and flax (Linum usitatissimum L ...
Shayeb Shahariar, Mervin St. Luce, Manjula Bandara, Charles M. Geddes, Kui Liu, Prabhath Lokuruge, Mohammad Khakbazan, Brian McConkey   +7 more
wiley   +1 more source

Functional Characterisation of Alpha-Galactosidase A Mutations as a Basis for a New Classification System in Fabry Disease [PDF]

, 2013
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.The study has been ...
Giese, A-K, Grittner, U, Kolodny, E, Lackner, KJ, Lukas, J, Markoff, A, Mascher, H, Meyer, W, Rolfs, A, Saviouk, V, Wree, P   +10 more
core   +3 more sources

Insights from meta‐analysis for efficient docosahexaenoic acid production in thraustochytrids through advanced cultivation and fermentation strategies

Biofuels, Bioproducts and Biorefining, Volume 20, Issue 2, Page 1041-1060, March/April 2026.
Abstract This systematic review examines strategies for docosahexaenoic acid (DHA) production by thraustochytrids, focusing on cultivation techniques, fermentation technologies, and carbon/nitrogen optimization to increase productivity. Among 169 eligible articles, the 100 most productive studies (0.7–10.3 g DHA L−1 per day) were analyzed. Quantitative
Jhiovana Cristielly Carrera Silva da Costa, Lucas Araújo Guimarães, Andre da Luz de Freitas, Luciana Porto de Souza Vandenberghe, Gilberto Vinícius de Melo Pereira, Carlos Ricardo Soccol, Hervé Louis Ghislain Rogez   +6 more
wiley   +1 more source

From variome to phenome : pathogenesis, diagnosis and management of ectopic mineralization disorders [PDF]

, 2015
Ectopic mineralization - inappropriate biomineralization in soft tissues - is a frequent finding in physiological aging processes and several common disorders, which can be associated with significant morbidity and mortality.
De Vilder, eva, Vanakker, Olivier
core   +2 more sources

From Fermentation to Functionality: Lipidomic Characterization and Index‐Based Evaluation of Plant‐Based Kefir

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
Lipidomic characterization and index‐based evaluation of plant‐based kefir. ABSTRACT This study aimed to characterize the fatty acid composition and to evaluate lipid quality indices of kefir produced with varying ratios of chestnut milk and reconstituted skim milk, using both traditional and commercial starter cultures.
Buse Usta‐Gorgun, Lutfiye Yilmaz‐Ersan   +1 more
wiley   +1 more source

Matrix Gla protein maintains normal and malignant hematopoietic progenitor cells by interacting with bone morphogenetic protein-4

Heliyon, 2020
Matrix Gla protein (MGP), a modulator of the BMP-SMAD signals, inhibits arterial calcification in a Glu γ-carboxylation dependent manner but the role of MGP highly expressed in a subset of bone marrow (BM) mesenchymal stem/stromal cells is unknown.
Kana Kuronuma, Aya Yokoi, Tomoya Fukuoka, Muneaki Miyata, Akio Maekawa, Satowa Tanaka, Leo Matsubara, Chie Goto, Miki Matsuo, Hao-Wei Han, Mai Tsuruta, Haruka Murata, Hikari Okamoto, Natsumi Hasegawa, Shigetaka Asano, Mitsuhiro Ito   +15 more
doaj   +1 more source

Matrix gla protein in xenopus laevis: molecular cloning, tissue distribution, and evolutionary considerations [PDF]

, 2001
Matrix Gla protein (MGP) belongs to the family of vitamin K-dependent, Gla-containing proteins and in higher vertebrates, is found in the extracellular matrix of mineralized tissues and soft tissues. MGP synthesis is highly regulated at the transcription
Bassez, Bergwitz, C. S. B. Viegas, Cancela, Cancela, Cancela, Cancela, Cancela, Carr, Celeste, Chomczynski, Felsenstein, Felsenstein, Fraser, Fraser, Gavaia, Hale, Hale, Huq, Ikeda, J. P. Reia, Kirfel, Li, Luo, M. C. P. Ohresser, M. K. Williamson, M. L. Cancela, Meyer, Meyer, Munroe, Nieuwkoop, Nishimoto, Otawara, P. A. Price, Pan, Parenti, Price, Price, Price, Price, Price, Price, Price, Price, Rannels, Rice, Sambrook, Sanger, Scrivastan, Sohma, Strickberger, Trueb, Virdi, Wiedemann, Yagami, Zhao   +55 more
core   +1 more source