Results 91 to 100 of about 135,583 (285)
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Multivariate Nonnegative Quadratic Mappings [PDF]
In this paper we study several issues related to the characterization of speci c classes of multivariate quadratic mappings that are nonnegative over a given domain, with nonnegativity de ned by a pre-speci ed conic order.In particular, we consider the ...
Luo, Z-Q, Sturm, J.F., Zhang, S.
core +1 more source
On the transpose map of matrix algebras [PDF]
Proceedings of the American Mathematical Society, 1983 It is shown that for the transpose map θ ( n ) \theta (n) of the n × n n \times n matrix algebra M n {M_n} , its k k th multiplicity map θ ( n
openaire +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Some Tauberian theorems for Euler and Borel summability
International Journal of Mathematics and Mathematical Sciences, 1980 The well-known summability methods of Euler and Borel are studied as mappings from ℓ1 into ℓ1. In this ℓ−ℓ setting, the following Tauberian results are proved: if x is a sequence that is mapped into ℓ1 by the Euler-Knopp method Er with r>0 (or the Borel ...
J. A. Fridy, K. L. Roberts
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
A New Sufficient Condition for Uniqueness in Continuous Games [PDF]
Consider the class of games in which each player chooses a strategy from a connected subset of the real line. Many oligopoly models fall into this class.
Seamus Hogan
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Developed matrix inequalities via positive multilinear mappings
Linear Algebra and its Applications, 2015 Utilizing the notion of positive multilinear mappings, we give some matrix inequalities. In particular, Choi--Davis--Jensen and Kantorovich type inequalities including positive multilinear mappings are presented.
Mahdi Dehghani, Mohsen Kian, Yuki Seo
openaire +3 more sources
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source