Results 81 to 90 of about 135,583 (285)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Conservation law of harmonic mappings in supercritical dimensions

Comptes Rendus. Mathématique
In this short note, we provide a partial extension of Rivière’s convervation law in higher dimensions under certain Lorentz integrability condition for the connection matrix.
Guo, Chang-Yu, Xiang, Chang-Lin
doaj   +1 more source

Nash equilibria set computing in finite extended games [PDF]

Computer Science Journal of Moldova, 2006
he Nash equilibria set (NES) is described as an intersection of graphs of best response mappings. The problem of NES computing for multi-matrix extended games is considered. A method for NES computing is studied.
Valeriu Ungureanu
doaj  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

The Application Domain of Infinite Matrices with Algorithms

Universal Journal of Mathematics and Applications, 2018
The purpose of this paper is twofold. First, we define the new spaces and investigate some topological and structural properties. Also, we compute dual spaces of new spaces which are help us in the characterization of matrix mappings.
Murat Kirişçi
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Related Suzuki-type fixed point theorems in ordered metric space

Fixed Point Theory and Applications, 2020
In this paper, we use Suzuki-type contraction to prove three fixed point theorems for generalized contractions in an ordered space equipped with two metrics; we obtain some generalizations of the Kannan fixed point theorem.
Outass Rida, Chaira Karim, Marhrani El Miloudi   +2 more
doaj   +1 more source

Term Mapping Using Matrix Operations

, 2008
We believe that gene name identification is a modular process involving term recognition, classification and mapping. This work's focus is on gene name mapping, and we assume that names are already recognized and classified. We use a combination of two methods to map recognized entities to their appropriate gene identifiers (Entrez GeneIDs): the ...
Krauthammer, Michael, Luong, Thaibinh
openaire   +3 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

The Abel-type transformations into ℓ

International Journal of Mathematics and Mathematical Sciences, 1999
Let t be a sequence in (0,1) that converges to 1, and define the Abel-type matrix Aα,t by ank=(k+α     k)tnk+1(1−tn)α+1 for α>−1. The matrix Aα,t determines a sequence-to-sequence variant of the Abel-type power series method of summability introduced by ...
Mulatu Lemma
doaj   +1 more source