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Integrin α2β1 Expression Regulates Matrix Metalloproteinase-1-Dependent Bronchial Epithelial Repair in Pulmonary Tuberculosis [PDF]
Frontiers in Immunology, 2018 Pulmonary tuberculosis (TB) is caused by inhalation of Mycobacterium tuberculosis, which damages the bronchial epithelial barrier to establish local infection.
Sara Brilha +8 more
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Inhibitory Antibodies Designed for Matrix Metalloproteinase Modulation [PDF]
Molecules, 2019 The family of matrix metalloproteinases (MMPs) consists of a set of biological targets that are involved in a multitude of severe pathogenic events such as different forms of cancers or arthritis.
Thomas Fischer, Rainer Riedl
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Journal of UOEH, 1997 Matrix-degrading enzymes, matrix metalloproteinases, are members of a unique family of Zinc-binding endopeptidases that are responsible for the metabolism of extracellular components in the tissue stroma. Their controlled expression is essential for normal processes such as wound healing and tissue remodeling, including embryogenesis.
Parsons, S. L. +4 more
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The role of MMP-2 and MMP-9 in the metastasis and development of hypopharyngeal carcinoma
Brazilian Journal of Otorhinolaryngology, 2021 Introduction: The role of matrix metalloproteinase-2 and 9 in the metastasis and development of hypopharyngeal carcinoma has not been clarified. Objectives: To observe the relationship between matrix metalloproteinase-2, matrix metalloproteinase-9 and ...
Zhe Song +5 more
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Frontiers in Immunology, 2022 There has been a growing interest in the presence and role of B cell aggregates within the central nervous system of multiple sclerosis patients. However, very little is known about the expression profile of molecules associated with these aggregates and
Rittika Chunder +8 more
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Regulation of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 in Abdominal Aortic Aneurysm
Cardiology Discovery, 2023 Abdominal aortic aneurysm (AAA) is a degenerative disease characterized by destruction and progressive expansion of the abdominal aortic wall. An AAA is typically defined as an enlargement of the abdominal aorta with diameter ≥3 cm or ≥50% greater than ...
Shuo Wang +3 more
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The American Journal of Pathology, 2012 Remodeling of extracellular matrix is crucial for many physiological (cell migration, proliferation, growth, and development) and pathological (remodeling of heart, carcinogenesis, metastasis, etc.) events. Thus, the interaction between cells and extracellular matrix plays a key role in normal development and differentiation of organism and many ...
Viola, Vargová +2 more
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Biomarkers of Skin Graft Healing in Venous Leg Ulcers
Acta Dermato-Venereologica, 2022 There is a need for biomarkers that predict the success of transplantation of venous leg ulcers (with autologous split-thickness skin grafts). The primary objective of this exploratory study was to investigate the association between split-thickness skin
Klaus Kirketerp-Møller +7 more
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The relationship between metastasis and mmp-9 in sheep with pulmonary adenocarcinomas [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2022 Th is study aimed to evaluate the role of Matrix Metalloproteinase-9 in the metastasis of ovine pulmonary adenocarcinoma cases by immunohistochemical methods.
Emin KARAKURT +5 more
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Current Medicinal Chemistry, 2010 Matrix metalloproteinases (MMPs), also known as matrixins, belong to a group of zinc-dependent proteins, which are thought to play a central role in the breakdown of extracellular matrix. Collagen, elastin, gelatin and casein are major components cleaved by MMPs.
O, Zitka +7 more
openaire +4 more sources