Identification of a novel role for matrix metalloproteinase-3 in the modulation of B cell responses in multiple sclerosis [PDF]
There has been a growing interest in the presence and role of B cell aggregates within the central nervous system of multiple sclerosis patients. However, very little is known about the expression profile of molecules associated with these aggregates and
Rittika Chunder +8 more
doaj +2 more sources
Correlation of matrix metalloproteinase 3 and matrix metalloproteinase 9 levels with non-motor symptoms in patients with Parkinson’s disease [PDF]
ObjectiveMatrix metalloproteinases (MMPs) are essential for tissue formation, neuronal network remodeling, and blood–brain barrier integrity. MMPs have been widely studied in acute brain diseases.
Chuan Ze Liu +30 more
doaj +2 more sources
New insights into the role of matrix metalloproteinase 3 (MMP3) in bone [PDF]
The Matrix Metalloproteinases are important regulators of bone metabolism and can influence bone mass and bone remodeling. We investigate the role of Matrix Metalloproteinase 3 (MMP3) on bone in mice, by using Mmp3 knockout (Mmp3 KO) in the context of ...
Frédéric Jehan +6 more
doaj +2 more sources
Increased Matrix Metalloproteinase-2 and Matrix Metalloproteinase-3 Concentrations in Corneal Epithelium of Patients with Recurrent Corneal Erosions [PDF]
Purpose. To assess the role of selected matrix metalloproteinases in defective corneal re-epithelization in patients with recurrent corneal erosions. Subjects.
Katarzyna Jadczyk-Sorek +4 more
doaj +2 more sources
Concentration of Serum Matrix Metalloproteinase-3 in Patients With Primary Biliary Cholangitis [PDF]
Background and AimsMetalloproteinases (MMPs) are involved in many distinct processes in the liver. Matrix metalloproteinase-3 (MMP-3) plays an important role in connective tissue remodeling, degradation of collagen (types II, III, IV, IX, and X ...
Alicja Bauer +2 more
doaj +2 more sources
Matrix Metalloproteinase 3: A Promoting and Destabilizing Factor in the Pathogenesis of Disease and Cell Differentiation [PDF]
Cells must alter their expression profiles and morphological characteristics but also reshape the extracellular matrix (ECM) to fulfill their functions throughout their lifespan.
Jiangtao Wan +6 more
doaj +2 more sources
Matrix metalloproteinase-3 in preeclamptic and normotensive pregnancies complicated by foetal growth restriction [PDF]
The aim of the present study was to assess the interrelationships between the level of matrix metalloproteinase-3 in the blood serum of pregnant women and the occurrence of pregnancy complications in the form of foetal growth restriction, idiopathic or ...
Marzena Laskowska +4 more
doaj +2 more sources
Epigenetic Regulation of Matrix Metalloproteinase-1 and -3 Expression in Mycobacterium tuberculosis Infection [PDF]
In pulmonary tuberculosis (TB), the inflammatory immune response against Mycobacterium tuberculosis (Mtb) is associated with tissue destruction and cavitation, which drives disease transmission, chronic lung disease, and mortality.
Rachel C. Moores +6 more
doaj +4 more sources
Galectin-3 and matrix metalloproteinases 2 and 9 in peripheral blood of gastric cancer patients
Background: High incidence of gastric cancer (GC), its aggressive clinical course, rapid tumor dissemination, low sensitivity to chemotherapy and lack of reliable laboratory diagnostic criteria urgently require a search for the most informative markers ...
Ekaterina A. Korotkova +8 more
doaj +1 more source
The aim of the research. To assess the influence of polymorphisms of the matrix metalloproteinase genes — 2 (rs2285053), — 3 (rs3025058), and — 13 (rs2252070) on the development of coronary atherosclerosis in patients with primary osteoarthritis ...
O. O. Portyannikova +3 more
doaj +1 more source

