Results 21 to 30 of about 240,479 (306)

Matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in diagnosis of pleural effusion of malignant origin [PDF]

open access: yes, 2016
OBJECTIVES: The aim of the present study was to evaluate the diagnostic accuracy of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in differentiating benign from malignant exudative pleural effusions.
D'Angelo, L.   +7 more
core   +1 more source

A Complete Expression Profile of Matrix-Degrading Metalloproteinases in Dupuytren’s Disease [PDF]

open access: yes, 2007
Dupuytren’s disease (DD) is a common fibrotic condition of the palmar fascia, leading to deposition of collagen-rich cords and finger contractions. The metzincin superfamily contains key enzymes in the turnover of collagen and other extracellular matrix ...
Adrian J. Chojnowski   +48 more
core   +1 more source

Ciprofloxacin enhances the stimulation of matrix metalloproteinase 3 expression by interleukin-1beta in human tendon-derived cells [PDF]

open access: yes, 2002
To determine whether the fluoroquinolone antibiotic ciprofloxacin, which can cause tendon pain and rupture in a proportion of treated patients, affects the expression of matrix metalloproteinases (MMPs) in human tendon-derived cells in culture.
Astrom   +16 more
core   +1 more source

Relationship of matrix metalloproteinase-3 -11715A/6A polymorphism (rs35068180) and dilated cardiomyopathy

open access: yesРоссийский кардиологический журнал, 2020
Aim. To study the relationship of matrix metalloproteinase-3 (MMP3) genetic polymorphism and dilated ischemic cardiomyopathy (DCM), as well as idiopathic cardiomyopathy (ICM) of unknown etiology.Material and methods.
S. Yu. Nikulina   +3 more
doaj   +1 more source

Impact of disease activity on impaired glucose metabolism in patients with rheumatoid arthritis

open access: yesArthritis Research & Therapy, 2021
Objective To explore glucose metabolism in rheumatoid arthritis (RA) and its association with insulin resistance (IR) risk factors and disease activity indicators, including matrix metalloproteinase-3 (MMP3). Methods This single-center study included 127
Gorica G. Ristić   +7 more
doaj   +1 more source

Acute- and late-phase matrix metalloproteinase (MMP)-9 activity is comparable in female and male rats after peripheral nerve injury. [PDF]

open access: yes, 2018
BACKGROUND:In the peripheral nerve, pro-inflammatory matrix metalloproteinase (MMP)-9 performs essential functions in the acute response to injury. Whether MMP-9 activity contributes to late-phase injury or whether MMP-9 expression or activity after ...
Angert, Mila   +6 more
core   +2 more sources

Matrix Metalloproteinase 3 Is a Mediator of Pulmonary Fibrosis [PDF]

open access: yesThe American Journal of Pathology, 2011
Idiopathic pulmonary fibrosis (IPF) may be triggered by epithelial injury that results in aberrant production of growth factors, cytokines, and proteinases, leading to proliferation of myofibroblasts, excess deposition of collagen, and destruction of the lung architecture. The precise mechanisms and key signaling mediators responsible for this aberrant
Cory M, Yamashita   +14 more
openaire   +2 more sources

A circular RNA derived from MMP9 facilitates oral squamous cell carcinoma metastasis through regulation of MMP9 mRNA stability

open access: yesCell Transplantation, 2019
Emerging evidence demonstrates that dysregulation of circular RNA is linked to tumorigenesis and aggressive progression. However, its role in oral squamous cell carcinoma remains largely uncharacterized.
Bing Xia   +4 more
doaj   +1 more source

CX3CL1 promotes MMP-3 production via the CX3CR1, c-Raf, MEK, ERK, and NF-κB signaling pathway in osteoarthritis synovial fibroblasts

open access: yesArthritis Research & Therapy, 2017
Background Osteoarthritis (OA) is a degenerative joint disease that affects the cartilage, synovium, and subchondral bone and is the leading cause of disability in older populations.
Sheng-Mou Hou, Chun-Han Hou, Ju-Fang Liu
doaj   +1 more source

Circulating Matrix Metalloproteinase 3 due to Myocardial Ischemia

open access: yesThe Heart Surgery Forum, 2009
Experimental data suggest that matrix metalloproteinases (MMPs) such as MMP-3 have a central role in the remodeling period after a myocardial infarction (MI). The aim of this study was to use an experimental small-animal model to investigate the fluctuation in MMP-3 levels occurring in vivo after an acute MI.We studied 13 New Zealand white rabbits ...
Siminelakis, S.   +6 more
openaire   +3 more sources

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