Results 31 to 40 of about 237,619 (312)

The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family [PDF]

open access: yes, 2015
The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) enzymes are secreted, multi-domain matrix-associated zinc metalloendopeptidases that have diverse roles in tissue morphogenesis and patho-physiological remodeling, in ...
A Colige   +145 more
core   +1 more source

MMP-2 together with MMP-9 overexpression correlated with lymph node metastasis and poor prognosis in early gastric carcinoma

open access: yesTumor Biology, 2017
The aim of this study was to correlate matrix metalloproteinase-2 and matrix metalloproteinase-9 expression with the clinicopathological features and outcome of patients with early gastric cancer and to clinically elucidate more information on the role ...
Zhihua Yao   +11 more
doaj   +1 more source

Matrix metalloproteinase 9 expression in canine mammary carcinomas

open access: yesBrazilian Journal of Veterinary Pathology, 2016
Mammary neoplasms are among the most common canine tumors, with high risk of invasion and metastasis. Important steps for these events are the loss of cell adhesion to the main tumor mass and extracellular matrix degradation.
Bianca C. Gramulia   +4 more
doaj   +1 more source

Enhancement of fibrinogen-triggered pro-coagulant activation of monocytes in vitro by matrix metalloproteinase-9 [PDF]

open access: yes, 2010
Background Interaction of fibrinogen with specific leukocyte integrins of monocytes may link coagulation and inflammation, however, the precise mechanism of fibrinogen leading to the pro-inflammatory and pro-coagulatory response on monocytes is yet ...
Nicole C Kaneider   +4 more
core   +1 more source

Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells [PDF]

open access: yes, 2007
MMP-9 (matrix metalloproteinase 9) plays a critical role in tumour progression. Although the biochemical properties of the secreted form of proMMP-9 are well characterized, little is known about the function and activity of cell surface-associated proMMP-
Egea, Virginia   +6 more
core   +1 more source

A circular RNA derived from MMP9 facilitates oral squamous cell carcinoma metastasis through regulation of MMP9 mRNA stability

open access: yesCell Transplantation, 2019
Emerging evidence demonstrates that dysregulation of circular RNA is linked to tumorigenesis and aggressive progression. However, its role in oral squamous cell carcinoma remains largely uncharacterized.
Bing Xia   +4 more
doaj   +1 more source

MMPs Regulate Neuronal Substance P After a Painful Equibiaxial Stretch in a Co-Culture Collagen Gel Model Simulating Injury of an Innervated Ligament

open access: yesFrontiers in Mechanical Engineering, 2022
Chronic joint pain is a major health problem that can result from abnormal loading of the innervated ligamentous capsule that surrounds synovial joints.
Meagan E. Ita   +2 more
doaj   +1 more source

Overexpression of the urokinase receptor splice variant uPAR-del4/5 in breast cancer cells affects cell adhesion and invasion in a dose-dependent manner and modulates transcription of tumor-associated genes [PDF]

open access: yes, 2012
mRNA levels of the urokinase receptor splice variant uPAR-del4/5 are associated with prognosis in breast cancer. Its overexpression in cancer cells affects tumor biologically relevant processes.
Baretton, Gustavo   +10 more
core   +1 more source

Relationships between MMP-2, MMP-9, and ADAMDEC1 serum and tissue levels in patients with colorectal cancer [PDF]

open access: yesAnnals of Coloproctology
Purpose Colorectal cancer (CRC) is the most common malignancy of the gastrointestinal system globally. Identifying specific gene expression patterns indicative of early-stage CRC could enable early diagnosis and rapid treatment initiation.
Zahra Mozooni   +5 more
doaj   +1 more source

Metalloproteinases and their Inhibitors under the Course of Immunostimulation by CPG-ODN and Specific Antigen Inhalation in Equine Asthma [PDF]

open access: yes, 2019
Objectives. Inhalation of immunostimulatory bacterial DNA segments (cytosine-phosphate-guanosine-oligodeoxynucleotides, CpG-ODN) normalizes clinical and cytologic parameters in severe equine asthma.
Barton, Ann Kristin   +5 more
core   +1 more source

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