Results 51 to 60 of about 75,485,891 (288)

The effect of Satureja sahendica Bornm essential oil on the expression of metalloproteases1, 2, 9 and 13 in bovine fibroblast - like syniviocytes [PDF]

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2023
Introduction: Osteoarthritis is a progressive, age-related disease characterized by cartilage destruction, subchondral bone formation, and inflammation of the synovial membrane.
Hossein Maghsoudi, Enayatollah Yazdanpanah, Ali Moheb   +2 more
doaj  

MMP-13, VEGF, and Disease Activity in a Cohort of Rheumatoid Arthritis Patients

Diagnostics, 2023
Identifying certain serum biomarkers associated with the degree of rheumatoid arthritis (RA) activity can provide us with a more accurate view of the evolution, prognosis, and future quality of life for these patients. Our aim was to analyze the presence
Mihail Virgil Boldeanu, Lidia Boldeanu, Oana Mariana Cristea, Dana Alexandra Ciobanu, Sabin Ioan Poenariu, Anda Lorena Dijmărescu, Andreea Lili Bărbulescu, Vlad Pădureanu, Teodor Nicuşor Sas, Ștefan Cristian Dinescu, Florentin Ananu Vreju, Horațiu Valeriu Popoviciu, Răzvan Adrian Ionescu   +12 more
doaj   +1 more source

N-Cadherin cleavage during activated hepatic stellate cell apoptosis is inhibited by tissue inhibitor of metalloproteinase-1. [In supplement: 11th International Symposium on the Cells of the Hepatic Sinusoid and their Relation to Other Cells] [PDF]

, 2004
Apoptosis of hepatic stellate cells (HSC) has previously been shown to occur during spontaneous resolution of experimental liver fibrosis. TIMP-1 has also been shown to have a key role because of its ability to inhibit apoptosis of HSC via matrix ...
Iredale, John P., Julian Waung, Derek Mann, R Christopher Benyon, Collins, Jane, Arthur, Michael J.P., Murphy, Frank, Nagase, Hideaki, Hideaki Nagase, John P Iredale, Mann, Derek, Frank Murphy, Waung, Julian, Jane Collins, Benyon, R. Christopher, Michael JP Arthur   +15 more
core   +1 more source

Matrix metalloproteinase-13 expression in the progression of colorectal adenoma to carcinoma

Tumor Biology, 2014
Most colorectal carcinomas (CRCs) are considered to arise from conventional adenoma based on the concept of the adenoma-carcinoma sequence. Matrix metalloproteinases (MMPs) are known to be overexpressed as normal mucosa progresses to adenomas and carcinomas.
Abd Al-Rahman Mohammad, Foda, Amira K, El-Hawary, Azza, Abdel-Aziz   +2 more
openaire   +2 more sources

Matrix Metalloproteinase-13 (MMP-13) Directly and Indirectly Promotes Tumor Angiogenesis [PDF]

Journal of Biological Chemistry, 2012
Matrix metalloproteinases (MMPs) are extracellular zinc-dependent endopeptidases involved in the degradation and remodeling of extracellular matrix in physiological and pathological processes. MMPs also have a role in cell proliferation, migration, differentiation, angiogenesis, and apoptosis. We previously identified cancer invasion-related factors by
Yasusei, Kudo, Shinji, Iizuka, Maki, Yoshida, Takaaki, Tsunematsu, Tomoyuki, Kondo, Ajiravudh, Subarnbhesaj, Elsayed M, Deraz, Samadarani B S M, Siriwardena, Hidetoshi, Tahara, Naozumi, Ishimaru, Ikuko, Ogawa, Takashi, Takata   +11 more
openaire   +2 more sources

Bone Marrow-derived Myofibroblasts Are the Providers of Pro-invasive Matrix Metalloproteinase 13 in Primary Tumor

Neoplasia: An International Journal for Oncology Research, 2012
Carcinoma-associated fibroblasts are key contributors of the tumor microenvironment that regulates carcinoma progression. They consist of a heterogeneous cell population with diverse origins, phenotypes, and functions.
Julie Lecomte, Anne Masset, Silvia Blacher, Ludovic Maertens, André Gothot, Marie Delgaudine, Françoise Bruyère, Oriane Carnet, Jenny Paupert, Martin Illemann, Jean-Michel Foidart, Ida K Lund, Gunilla Høyer-Hansen, Agnes Noel   +13 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Gender-dependent differences in plasma matrix metalloproteinase-8 elevated in pulmonary tuberculosis [PDF]

, 2014
Tuberculosis (TB) remains a global health pandemic and greater understanding of underlying pathogenesis is required to develop novel therapeutic and diagnostic approaches.
Sandhu, G, Christopher H. Woelk, Carlton A. W. Evans, Gurjinder Sandhu (161147), Borislav D. Dimitrov (687966), Gurjinder Sandhu, Woelk Christopher H., Liku B. Tezera, Akul Singhania, Thomas, Richard, Agranoff Dan, Sandhu Gurjinder, Liku B. Tezera (405129), Paul T. Elkington, Christopher H. Woelk (195217), Tezera, LB, Friedland Jon S., Jon S Friedland, Sathyamoorthy, Tarangini, Dimitrov, Borislav D., Sathyamoorthy, T, Singhania, A, Elkington, Paul T., Evans Carlton A. W., Agranoff, Dan, Evans, CAW, Richard Thomas, Elkington Paul T., Dimitrov, BD, Borislav D Dimitrov, Friedland, Jon S., Carlton A. W. Evans (687967), Christopher H Woelk, Dan Agranoff, Paul T Elkington, Paul T. Elkington (364501), Tarangini Sathyamoorthy (687964), Agranoff, D, Jon S. Friedland (161158), Tezera, Liku B., Sathyamoorthy Tarangini, Woelk, Christopher H., Borislav D. Dimitrov, Richard Thomas (687965), Akul Singhania (502117), Evans, Carlton A.W., Singhania, Akul, Jon S. Friedland, Tarangini Sathyamoorthy, Liku B Tezera, Sandhu, Gurjinder, Friedland, JS, Carlton A W Evans, Tezera Liku B., Thomas, R, Elkington, PT, Thomas Richard, Woelk, CH, Singhania Akul, Dan Agranoff (377996), Dimitrov Borislav D.   +60 more
core   +1 more source

Proteomic biomarkers in rotator cuff disease: Current evidence and translational implications from a systematic review and network analysis

Journal of Orthopaedic Translation
Background: Rotator cuff disorders are among the most common causes of shoulder pain and dysfunction, primarily driven by chronic inflammation and degenerative changes in tendon tissue.
Elvira Immacolata Parrotta, Giorgia Lucia Benedetto, Giovanni Cuda, Raffaele Covello, Umile Giuseppe Longo, Arianna Carnevale, Olimpio Galasso, Giorgio Gasparini, Michele Mercurio   +8 more
doaj   +1 more source

Matrix metalloproteinase 13 (collagenase 3) in human rheumatoid synovium [PDF]

Arthritis & Rheumatism, 1997
AbstractObjective. To show the eventual presence and extent of production of matrix metalloproteinase 13 (MMP‐13, or collagenase 3) in rheumatoid synovial tissue samples and extracts, and to assess the inhibition characteristics of recombinant MMP‐13.Methods.
O, Lindy, Y T, Konttinen, T, Sorsa, Y, Ding, S, Santavirta, A, Ceponis, C, López-Otín   +6 more
openaire   +2 more sources