Results 41 to 50 of about 126,856 (109)

Flaccidoxide-13-Acetate Extracted from the Soft Coral Cladiella kashmani Reduces Human Bladder Cancer Cell Migration and Invasion through Reducing Activation of the FAK/PI3K/AKT/mTOR Signaling Pathway

Molecules, 2017
Metastasis of cancer is the cause of the majority of cancer deaths. Active compound flaccidoxide-13-acetate, isolated from the soft coral Cladiella kashmani, has been found to exhibit anti-tumor activity.
Choo-Aun Neoh, Wen-Tung Wu, Guo-Fong Dai, Jui-Hsin Su, Chih-I Liu, Tzu-Rong Su, Yu-Jen Wu   +6 more
doaj   +1 more source

Comparison of the effects of enamel matrix derivative and mineral trioxide aggregate on the mineralization potential of human cementum-derived cells

Journal of Dental Sciences, 2011
Background/purpose: Cementogenesis is a critical event in the repair of endodontic perforations and the enamel matrix derivative (EMD) was reported to induce cementogenesis when used in periodontal disease.
Hyunsook Chung, Wonkyung Yang, Miri Kim, Hyunjung Ko   +3 more
doaj   +1 more source

Isoliquiritigenin Inhibits IL-1β-Induced Production of Matrix Metalloproteinase in Articular Chondrocytes

Molecular Therapy: Methods & Clinical Development, 2018
Osteoarthritis (OA) is a major joint disease in which inflammatory cytokine interleukin-1β (IL-1β) and matrix metalloproteinases (MMPs) play a pivotal role. Isoliquiritigenin has been reported to have anti-inflammation activity. In this study, the effect
Lei Zhang, Shiyun Ma, Hang Su, Jiaxiang Cheng   +3 more
doaj   +1 more source

The Role of Matrix Metalloproteinase 13 and Vitamin D in Osteoarthritis: A Hospital-Based Observational Study. [PDF]

Cureus, 2023
Kumar P, Kumar S, Abhilasha A, Singh A, Kumar U.   +4 more
europepmc   +1 more source

Molecular Dynamics Simulations of Matrix Metalloproteinase 13 and the Analysis of the Specificity Loop and the S1'-Site. [PDF]

Int J Mol Sci, 2023
Choi JY, Chung E.
europepmc   +1 more source

Expressions of insulin-like growth factor-1, interleukin-1β, and matrix metalloproteinase-13 in patients with knee osteoarthritis and their associations with the severity

Romanian Journal of Laboratory Medicine
A key factor in the pathogenesis of osteoarthritis is an imbalance in cytokines, favoring proinflammatory activity. This study aimed to explore the expressions of insulin-like growth factor-1 (IGF-1), interleukin-1β (IL-β) and matrix metalloproteinase-13
Zheng Nan
doaj   +1 more source

Matrix metalloproteinase-13 downregulation and potential cartilage protective action of the Korean Red Ginseng preparation

Journal of Ginseng Research, 2015
Background: The present study was designed to prepare and find the optimum active preparation or fraction from Korea Red Ginseng inhibiting matrix metalloproteinase-13 (MMP-13) expression, because MMP-13 is a pivotal enzyme to degrade the collagen matrix
Je Hyeong Lee, Omer Shehzad, Sung Kwon Ko, Yeong Shik Kim, Hyun Pyo Kim   +4 more
doaj   +1 more source

Activation of PPARs α, β/δ, and γ Impairs TGF-β1-Induced Collagens' Production and Modulates the TIMP-1/MMPs Balance in Three-Dimensional Cultured Chondrocytes

PPAR Research, 2010
Background and Purpose. We investigated the potency of Peroxisome Proliferators-Activated Receptors (PPARs) α, β/δ, and γ agonists to modulate Transforming Growth Factor-β1 (TGF-β1-) induced collagen production or changes in Tissue Inhibitor of Matrix ...
Paul-Emile Poleni, Stephanie Etienne, Emilie Velot, Patrick Netter, Arnaud Bianchi   +4 more
doaj   +1 more source

Proinflammatory and Anabolic Gene Expression Effects of Platelet-Rich Gel Supernatants on Equine Synovial Membrane Explants Challenged with Lipopolysaccharide

Veterinary Medicine International, 2017
Platelet-rich plasma (PRP) preparations are used in horses with osteoarthritis (OA). However, some controversies remain regarding the ideal concentration of platelets and leukocytes to produce an adequate anti-inflammatory and anabolic response in the ...
Jorge U. Carmona, Diana L. Ríos, Catalina López, María E. Álvarez, Jorge E. Pérez   +4 more
doaj   +1 more source

[Retracted] MicroRNA‑143 inhibits cell migration and invasion by targeting matrix metalloproteinase 13 in prostate cancer. [PDF]

Mol Med Rep, 2023
Wu D, Huang P, Wang L, Zhou Y, Pan H, Qu P.   +5 more
europepmc   +1 more source