Results 31 to 40 of about 126,856 (109)

MMP-13, VEGF, and Disease Activity in a Cohort of Rheumatoid Arthritis Patients

Diagnostics, 2023
Identifying certain serum biomarkers associated with the degree of rheumatoid arthritis (RA) activity can provide us with a more accurate view of the evolution, prognosis, and future quality of life for these patients. Our aim was to analyze the presence
Mihail Virgil Boldeanu, Lidia Boldeanu, Oana Mariana Cristea, Dana Alexandra Ciobanu, Sabin Ioan Poenariu, Anda Lorena Dijmărescu, Andreea Lili Bărbulescu, Vlad Pădureanu, Teodor Nicuşor Sas, Ștefan Cristian Dinescu, Florentin Ananu Vreju, Horațiu Valeriu Popoviciu, Răzvan Adrian Ionescu   +12 more
doaj   +1 more source

Bone Marrow-derived Myofibroblasts Are the Providers of Pro-invasive Matrix Metalloproteinase 13 in Primary Tumor

Neoplasia: An International Journal for Oncology Research, 2012
Carcinoma-associated fibroblasts are key contributors of the tumor microenvironment that regulates carcinoma progression. They consist of a heterogeneous cell population with diverse origins, phenotypes, and functions.
Julie Lecomte, Anne Masset, Silvia Blacher, Ludovic Maertens, André Gothot, Marie Delgaudine, Françoise Bruyère, Oriane Carnet, Jenny Paupert, Martin Illemann, Jean-Michel Foidart, Ida K Lund, Gunilla Høyer-Hansen, Agnes Noel   +13 more
doaj   +1 more source

Proteomic biomarkers in rotator cuff disease: Current evidence and translational implications from a systematic review and network analysis

Journal of Orthopaedic Translation
Background: Rotator cuff disorders are among the most common causes of shoulder pain and dysfunction, primarily driven by chronic inflammation and degenerative changes in tendon tissue.
Elvira Immacolata Parrotta, Giorgia Lucia Benedetto, Giovanni Cuda, Raffaele Covello, Umile Giuseppe Longo, Arianna Carnevale, Olimpio Galasso, Giorgio Gasparini, Michele Mercurio   +8 more
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Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF

EMBO Molecular Medicine, 2013
Several pathological processes, such as sepsis and inflammatory bowel disease (IBD), are associated with impairment of intestinal epithelial barrier. Here, we investigated the role of matrix metalloproteinase MMP13 in these diseases.
Roosmarijn E. Vandenbroucke, Eline Dejonckheere, Filip Van Hauwermeiren, Sofie Lodens, Riet De Rycke, Elien Van Wonterghem, An Staes, Kris Gevaert, Carlos López‐Otin, Claude Libert   +9 more
doaj   +1 more source

Effects of Flavonoids on Matrix Metalloproteinase-13 Expression of Interleukin-1β–Treated Articular Chondrocytes and Their Cellular Mechanisms: Inhibition of c-Fos/AP-1 and JAK/STAT Signaling Pathways

Journal of Pharmacological Sciences, 2011
.: To identify the therapeutic potential for cartilage degradation and its action mechanisms, the effects of naturally-occurring flavonoids on matrix metalloproteinase-13 (MMP-13) induction were examined in the human chondrocyte cell line SW1353 ...
Hyun Lim, Haeil Park, Hyun Pyo Kim
doaj   +1 more source

Effect of Progesterone on Expression of MMP7 and MMP13 in Lungs of Female Mice

Iranian Journal of Allergy, Asthma and Immunology, 2018
Gender medicine is a new era of science which focuses on the impact of sex hormones and gender on normal physiology, pathobiology and clinical features of diseases.
Elahe Izadi, Fateme Vafashoar, Paria Jorbozedar, Pendar Safari, Mohamad Ali Assarehzadegan, Hadi Poormoghim, Jalil Kuhpayezadeh, Nazanin Mojtabavi   +7 more
doaj   +1 more source

Matrix metalloproteinase 13 (MMP13) is a direct target of osteoblast-specific transcription factor osterix (Osx) in osteoblasts. [PDF]

PLoS ONE, 2012
Osterix (Osx) is an osteoblast-specific transcription factor required for bone formation and osteoblast differentiation from mesenchymal stem cells. In Osx-null mice, no bone formation occurs. Matrix metalloproteinase 13 (MMP13) is a member of the matrix
Chi Zhang, Wanjin Tang, Yang Li
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Matrix metalloproteinase-13 participates in neuroprotection and neurorepair after cerebral ischemia in mice

Neurobiology of Disease, 2016
New neuroreparative and neuroprotective therapies are being sought to treat stroke patients. One approach is the remodeling of extracellular matrix, which participates in both brain injury and neurovascular repair when matrix metalloproteinases (MMPs ...
Feifei Ma, Pablo Martínez-San Segundo, Verónica Barceló, Anna Morancho, Marina Gabriel-Salazar, Dolors Giralt, Joan Montaner, Anna Rosell   +7 more
doaj   +1 more source

Dietary Lecithin Decreases Skeletal Muscle COL1A1 and COL3A1 Gene Expression in Finisher Gilts

Animals, 2016
The purpose of this study was to investigate the effect of dietary lecithin on skeletal muscle gene expression of collagen precursors and enzymes involved in collagen synthesis and degradation.
Henny Akit, Cherie Collins, Fahri Fahri, Alex Hung, Daryl D’Souza, Brian Leury, Frank Dunshea   +6 more
doaj   +1 more source

Diagnostic Value of Serum and Saliva Matrix Metalloproteinase13 (MMP13) in Oral Squamous Cell Carcinoma

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2020
BACKGROUND AND OBJECTIVE: Matrix metalloproteinases (MMPs) are a group of enzymes responsible for extracellular matrix breakdown. Increased activity of type 13 is involved in invasion of oral squamous cell carcinoma.
T Ghanbarnia, M Seyedmajidi, M Mehryari, A Bijani, M Pooramir, R Foroughi   +5 more
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