Results 31 to 40 of about 700,907 (294)

ELISA study of matrix metalloproteinases 2, 7, 9 and their type 2 tissue inhibitor in the tumors of gastric cancer patients: clinical and pathologic correlations

Alʹmanah Kliničeskoj Mediciny, 2018
Background: Over the last 10 years the incidence of gastric cancer has declined significantly. Nevertheless, it remains one of the most prevalent malignancies both in Russia and worldwide.
E. S. Gershtein, A. A. Ivannikov, V. L. Chang, N. A. Ognerubov, М. M. Davydov, I. S. Stilidi, N. E. Kushlinskii   +6 more
doaj   +1 more source

The extracellular matrix degradation markers as predictors of left ventricular systolic dysfunction among patients with STEMI

Сучасні медичні технології, 2021
The purpose of the study. To determine predictor value of the extracellular matrix degradation markers relative to the occurrence of left ventricular systolic dysfunction among patients with STEMI determined. Materials and methods.
I. M. Fushtey, E. V. Sid
doaj   +1 more source

Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) Binds to the Catalytic Domain of the Cell Surface Receptor, Membrane Type 1-Matrix Metalloproteinase 1 (MT1-MMP)*

Journal of Biological Chemistry, 1998
It has been proposed that tissue inhibitor of metalloproteinase-2 (TIMP-2), in stoichiometric concentrations, serves as an intermediate in progelatinase A activation by binding to activated membrane type 1-matrix metalloproteinase 1 (MT1-MMP) on the ...
S. Zucker, M. Drews, Cathleen Conner, H. Foda, Y. DeClerck, K. Langley, W. Bahou, A. Docherty, Jian Cao   +8 more
semanticscholar   +1 more source

Relationships between MMP-2, MMP-9, and ADAMDEC1 serum and tissue levels in patients with colorectal cancer [PDF]

Annals of Coloproctology
Purpose Colorectal cancer (CRC) is the most common malignancy of the gastrointestinal system globally. Identifying specific gene expression patterns indicative of early-stage CRC could enable early diagnosis and rapid treatment initiation.
Zahra Mozooni, Kiana Khajeh Amiri, Nafiseh Golestani, Alireza Shahmohammadi, Sara Minaeian, Leyla Bahadorizadeh   +5 more
doaj   +1 more source

Osteopontin Stimulates Tumor Growth and Activation of Promatrix Metalloproteinase-2 through Nuclear Factor-κB-mediated Induction of Membrane Type 1 Matrix Metalloproteinase in Murine Melanoma Cells*

Journal of Biological Chemistry, 2001
Matrix metalloproteinases (MMPs) degrade the extracellular matrix (ECM) and play critical roles in tissue repair, tumor invasion, and metastasis. MMPs are regulated by different cytokines, ECM proteins, and other factors.
S. Philip, Anuradha Bulbule, Gopal C. Kundu   +2 more
semanticscholar   +1 more source

A Theoretical Model of Type I Collagen Proteolysis by Matrix Metalloproteinase (MMP) 2 and Membrane Type 1 MMP in the Presence of Tissue Inhibitor of Metalloproteinase 2*[boxs]

Journal of Biological Chemistry, 2004
One well documented family of enzymes responsible for the proteolytic processes that occur in the extracellular matrix is the soluble and membrane-associated matrix metalloproteinases.
Emmanouil D. Karagiannis, A. Popel
semanticscholar   +1 more source

Molecular interactions of tannic acid and matrix metalloproteinases 2 and 9

Computational and Structural Biotechnology Journal, 2023
Tannic acid (TA) has antibacterial, antioxidant, and anti-inflammatory properties and acts as an adhesive, hemostatic, and crosslinking agent in hydrogels.
Ya-Tang Chiang, Yu-Bai Xiao, Shan-hui Hsu, Shu-Wei Chang, Chia-Ching Chou   +4 more
doaj   +1 more source

Matrix Metalloproteinase 2 Is Required for Ovulation and Corpus Luteum Formation in Drosophila

PLoS Genetics, 2015
Ovulation is critical for successful reproduction and correlates with ovarian cancer risk, yet genetic studies of ovulation have been limited. It has long been thought that the mechanism controlling ovulation is highly divergent due to speciation and ...
Lylah D Deady, Wei Shen, S. Mosure, A. Spradling, Jianjun Sun   +4 more
semanticscholar   +1 more source

Increased Matrix Metalloproteinase-2 and Matrix Metalloproteinase-3 Concentrations in Corneal Epithelium of Patients with Recurrent Corneal Erosions

Journal of Ophthalmology, 2022
Purpose. To assess the role of selected matrix metalloproteinases in defective corneal re-epithelization in patients with recurrent corneal erosions. Subjects.
Katarzyna Jadczyk-Sorek, Wojciech Garczorz, Beata Bubała-Stachowicz, Tomasz Francuz, Ewa Mrukwa-Kominek   +4 more
doaj   +1 more source

In vivo and in vitro efficacy of crocin against Echinococcus multilocularis

Parasites & Vectors, 2021
Background Alveolar echinococcosis (AE) is a fatal zoonosis caused by the larvae of Echinococcus multilocularis. However, current chemotherapy treatment options are based on benzimidazoles [albendazole (ABZ) and mebendazole], which have limited efficacy.
Chuanchuan Liu, Haining Fan, Lu Guan, Ri-li Ge, Lan Ma   +4 more
doaj   +1 more source