Results 21 to 30 of about 151,446 (255)

Microtubule-Dependent Matrix Metalloproteinase-2/Matrix Metalloproteinase-9 Exocytosis [PDF]

Cancer Research, 2004
Abstract Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that cleave and degrade a wide spectrum of extracellular matrix components. By enhancing turnover of extracellular matrix, MMP activity is also known to play a key role in tumor cell invasion.
Eva-Maria Schnaeker, Rainer Ossig, Thomas Ludwig, Rita Dreier, Hans Oberleithner, M. Wilhelmi, Stefan W. Schneider   +6 more
openaire   +1 more source

Expression of matrix metalloproteinase-2 and 9 with their inhibitors, tissue inhibitors of metalloproteinase-1 and 2 in oral lichen planus

Journal of Orofacial Sciences, 2014
Objectives: The study aims to explore the expression of the matrix metalloproteinases (MMP-2, -9) and their inhibitors (tissue inhibitors of metalloproteinase [TIMP]-1, -2) as well as the correlation between them in the different morphological forms of ...
Natheer Hashim Al-Rawi, Thaer Kassim Al-Kassam, Ahlam Hameed Majeed   +2 more
doaj   +1 more source

ELISA study of matrix metalloproteinases 2, 7, 9 and their type 2 tissue inhibitor in the tumors of gastric cancer patients: clinical and pathologic correlations

Alʹmanah Kliničeskoj Mediciny, 2018
Background: Over the last 10 years the incidence of gastric cancer has declined significantly. Nevertheless, it remains one of the most prevalent malignancies both in Russia and worldwide.
E. S. Gershtein, A. A. Ivannikov, V. L. Chang, N. A. Ognerubov, М. M. Davydov, I. S. Stilidi, N. E. Kushlinskii   +6 more
doaj   +1 more source

The extracellular matrix degradation markers as predictors of left ventricular systolic dysfunction among patients with STEMI

Сучасні медичні технології, 2021
The purpose of the study. To determine predictor value of the extracellular matrix degradation markers relative to the occurrence of left ventricular systolic dysfunction among patients with STEMI determined. Materials and methods.
I. M. Fushtey, E. V. Sid
doaj   +1 more source

Relationships between MMP-2, MMP-9, and ADAMDEC1 serum and tissue levels in patients with colorectal cancer [PDF]

Annals of Coloproctology
Purpose Colorectal cancer (CRC) is the most common malignancy of the gastrointestinal system globally. Identifying specific gene expression patterns indicative of early-stage CRC could enable early diagnosis and rapid treatment initiation.
Zahra Mozooni, Kiana Khajeh Amiri, Nafiseh Golestani, Alireza Shahmohammadi, Sara Minaeian, Leyla Bahadorizadeh   +5 more
doaj   +1 more source

Increased Matrix Metalloproteinase-2 and Matrix Metalloproteinase-3 Concentrations in Corneal Epithelium of Patients with Recurrent Corneal Erosions

Journal of Ophthalmology, 2022
Purpose. To assess the role of selected matrix metalloproteinases in defective corneal re-epithelization in patients with recurrent corneal erosions. Subjects.
Katarzyna Jadczyk-Sorek, Wojciech Garczorz, Beata Bubała-Stachowicz, Tomasz Francuz, Ewa Mrukwa-Kominek   +4 more
doaj   +1 more source

Molecular interactions of tannic acid and matrix metalloproteinases 2 and 9

Computational and Structural Biotechnology Journal, 2023
Tannic acid (TA) has antibacterial, antioxidant, and anti-inflammatory properties and acts as an adhesive, hemostatic, and crosslinking agent in hydrogels.
Ya-Tang Chiang, Yu-Bai Xiao, Shan-hui Hsu, Shu-Wei Chang, Chia-Ching Chou   +4 more
doaj   +1 more source

In vivo and in vitro efficacy of crocin against Echinococcus multilocularis

Parasites & Vectors, 2021
Background Alveolar echinococcosis (AE) is a fatal zoonosis caused by the larvae of Echinococcus multilocularis. However, current chemotherapy treatment options are based on benzimidazoles [albendazole (ABZ) and mebendazole], which have limited efficacy.
Chuanchuan Liu, Haining Fan, Lu Guan, Ri-li Ge, Lan Ma   +4 more
doaj   +1 more source

Serum matrix metalloproteinase 2 and tissue inhibitor of matrix metalloproteinases 2 in esophageal cancer patients

Folia Histochemica et Cytobiologica, 2012
The positive expression of MMP-2 and TIMP-2 were found in esophageal cancer (EC) tissue and correlated with cancer stage and clinico-pathological features of tumor and patients' survival. However, little is known about serum levels of those proteins in EC patients. The aim of the present study was to investigate the diagnostic significance of MMP-2 and
Magdalena, Groblewska, Barbara, Mroczko, Miroslaw, Kozlowski, Jacek, Niklinski, Jerzy, Laudanski, Maciej, Szmitkowski   +5 more
openaire   +3 more sources

Biomarkers of Skin Graft Healing in Venous Leg Ulcers

Acta Dermato-Venereologica, 2022
There is a need for biomarkers that predict the success of transplantation of venous leg ulcers (with autologous split-thickness skin grafts). The primary objective of this exploratory study was to investigate the association between split-thickness skin
Klaus Kirketerp-Møller, Petra Doerfler, Nicole Schoefmann, Barbara Wolf-Winiski, Omid Niazi, Vibeke Pless, Tonny Karlsmark, Magnus Ågren   +7 more
doaj   +1 more source