Results 1 to 10 of about 99,179 (264)

Epigenetic Regulation of Matrix Metalloproteinase-1 and -3 Expression in Mycobacterium tuberculosis Infection [PDF]

Frontiers in Immunology, 2017
In pulmonary tuberculosis (TB), the inflammatory immune response against Mycobacterium tuberculosis (Mtb) is associated with tissue destruction and cavitation, which drives disease transmission, chronic lung disease, and mortality.
Rachel C. Moores, Sara Brilha, Sara Brilha, Frans Schutgens, Paul T. Elkington, Paul T. Elkington, Jon S. Friedland   +6 more
doaj   +4 more sources

Identification of a novel role for matrix metalloproteinase-3 in the modulation of B cell responses in multiple sclerosis

Frontiers in Immunology, 2022
There has been a growing interest in the presence and role of B cell aggregates within the central nervous system of multiple sclerosis patients. However, very little is known about the expression profile of molecules associated with these aggregates and
Rittika Chunder, Rittika Chunder, Verena Schropp, Verena Schropp, Samir Jabari, Manuel Marzin, Sandra Amor, Stefanie Kuerten, Stefanie Kuerten   +8 more
doaj   +1 more source

Correlation of matrix metalloproteinase 3 and matrix metalloproteinase 9 levels with non-motor symptoms in patients with Parkinson’s disease

Frontiers in Aging Neuroscience, 2022
ObjectiveMatrix metalloproteinases (MMPs) are essential for tissue formation, neuronal network remodeling, and blood–brain barrier integrity. MMPs have been widely studied in acute brain diseases.
Chuan Ze Liu, Chuan Ze Liu, Da Shuai Guo, Da Shuai Guo, Jian Jun Ma, Jian Jun Ma, Jian Jun Ma, Lin Rui Dong, Lin Rui Dong, Qing Qing Chang, Qing Qing Chang, Hong Qi Yang, Hong Qi Yang, Hong Qi Yang, Ke Ke Liang, Ke Ke Liang, Xiao Huan Li, Xiao Huan Li, Da Wei Yang, Da Wei Yang, Yong Yan Fan, Yong Yan Fan, Qi Gu, Qi Gu, Qi Gu, Si Yuan Chen, Si Yuan Chen, Si Yuan Chen, Dong Sheng Li, Dong Sheng Li, Dong Sheng Li   +30 more
doaj   +1 more source

Galectin-3 and matrix metalloproteinases 2 and 9 in peripheral blood of gastric cancer patients

Alʹmanah Kliničeskoj Mediciny, 2023
Background: High incidence of gastric cancer (GC), its aggressive clinical course, rapid tumor dissemination, low sensitivity to chemotherapy and lack of reliable laboratory diagnostic criteria urgently require a search for the most informative markers ...
Ekaterina A. Korotkova, Elena S. Gershtein, Ekaterina V. Samoilova, Irina O. Goryacheva, Aram P. Petrosyan, Natalia N. Zybina, Oleg O. Yanushevich, Ivan S. Stilidi, Nikolay E. Kushlinskii   +8 more
doaj   +1 more source

Role of Gene Polymorphisms of Matrix Metalloproteinases-2, -3 and -13 in the Development of Coronary Artery Atherosclerosis in Patients with Primary Polyosteoarthrosis

Архивъ внутренней медицины, 2020
The aim of the research. To assess the influence of polymorphisms of the matrix metalloproteinase genes — 2 (rs2285053), — 3 (rs3025058), and — 13 (rs2252070) on the development of coronary atherosclerosis in patients with primary osteoarthritis ...
O. O. Portyannikova, E. N. Romanova, A. V. Govorin, S. M. Tsvinger   +3 more
doaj   +1 more source

Leptin and Pro-Inflammatory Stimuli Synergistically Upregulate MMP-1 and MMP-3 Secretion in Human Gingival Fibroblasts. [PDF]

PLoS ONE, 2016
Gingival fibroblast-mediated extracellular matrix remodelling is implicated in the pathogenesis of periodontitis, yet the stimuli that regulate this response are not fully understood.
Rachel C Williams, Andrew J Skelton, Stephen M Todryk, Andrew D Rowan, Philip M Preshaw, John J Taylor   +5 more
doaj   +1 more source

Increased Matrix Metalloproteinase-2 and Matrix Metalloproteinase-3 Concentrations in Corneal Epithelium of Patients with Recurrent Corneal Erosions

Journal of Ophthalmology, 2022
Purpose. To assess the role of selected matrix metalloproteinases in defective corneal re-epithelization in patients with recurrent corneal erosions. Subjects.
Katarzyna Jadczyk-Sorek, Wojciech Garczorz, Beata Bubała-Stachowicz, Tomasz Francuz, Ewa Mrukwa-Kominek   +4 more
doaj   +1 more source

Impaired Expression of Membrane Type-2 and Type-3 Matrix Metalloproteinases in Endometriosis but Not in Adenomyosis

Diagnostics, 2022
Matrix metalloproteinases (MMPs) play an important role in menstruation and endometriosis; however, the membrane-type matrix metalloproteinases (MT-MMPs) are not well studied in endometriosis and adenomyosis.
Jane B. Maoga, Muhammad A. Riaz, Agnes N. Mwaura, Georgios Scheiner-Bobis, Ezekiel Mecha, Charles O. A. Omwandho, Ivo Meinhold-Heerlein, Lutz Konrad   +7 more
doaj   +1 more source

New insights into the role of matrix metalloproteinase 3 (MMP3) in bone

FASEB BioAdvances, 2022
The Matrix Metalloproteinases are important regulators of bone metabolism and can influence bone mass and bone remodeling. We investigate the role of Matrix Metalloproteinase 3 (MMP3) on bone in mice, by using Mmp3 knockout (Mmp3 KO) in the context of ...
Frédéric Jehan, Mylène Zarka, Guillaume dela Houssaye, Joëlle Veziers, Agnès Ostertag, Martine Cohen‐Solal, Valérie Geoffroy   +6 more
doaj   +1 more source

Curcuminoids extract, hydrolyzed collagen and green tea extract synergically inhibit inflammatory and catabolic mediator's synthesis by normal bovine and osteoarthritic human chondrocytes in monolayer. [PDF]

PLoS ONE, 2015
The main objective of this study was to assess the in vitro effects of curcuminoids extract, hydrolyzed collagen and green tea extract in normal bovine chondrocytes and osteoarthritic human chondrocytes cultured in monolayer. This study also investigated
Fanny Comblain, Christelle Sanchez, Isabelle Lesponne, Marc Balligand, Samuel Serisier, Yves Henrotin   +5 more
doaj   +1 more source