Results 11 to 20 of about 99,179 (264)

Matrix Metalloproteinase 3 Polymorphism [PDF]

Clinical Cancer Research, 2004
Abstract Purpose: Treatment of head and neck cancer often associates different therapeutic modalities, including surgery, radiotherapy, and chemotherapy. In an attempt to optimize therapeutics, the identification of molecular markers linked to response to chemotherapy remains important.
Hélène Blons, Sophie Gad, Franck Zinzindohoué, Isabelle Manière, Janie Beauregard, David Tregouet, Daniel Brasnu, Philippe Beaune, Ollivier Laccourreye, Pierre Laurent-Puig   +9 more
openaire   +1 more source

Matrix metalloproteinase-3 (MMP-3)–mediated gene therapy for glaucoma

Science Advances, 2023
Approximately 80 million people globally are affected by glaucoma, with a projected increase to over 110 million by 2040. Substantial issues surrounding patient compliance remain with topical eye drops, and up to 10% of patients become treatment resistant, putting them at risk of permanent vision loss.
O’Callaghan, Jeffrey, Delaney, Conor, O’Connor, Merissa, van Batenburg-Sherwood, Joseph, Schicht, Martin, Lütjen-Drecoll, Elke, Hudson, Natalie, Ni Dhubhghaill, Sorcha, Humphries, Peter, Stanley, Chris, Keravala, Annahita, Chalberg, Thomas, Lawrence, Matthew S., Campbell, Matthew   +13 more
openaire   +6 more sources

Pyrone-based inhibitors of metalloproteinase types 2 and 3 may work as conformation-selective inhibitors. [PDF]

, 2011
Matrix metalloproteinases are zinc-containing enzymes capable of degrading all components of the extracellular matrix. Owing to their role in human disease, matrix metalloproteinase have been the subject of extensive study.
de Oliveira, César AF, Durrant, Jacob D, McCammon, J Andrew   +2 more
core   +1 more source

The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family [PDF]

, 2015
The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) enzymes are secreted, multi-domain matrix-associated zinc metalloendopeptidases that have diverse roles in tissue morphogenesis and patho-physiological remodeling, in ...
A Colige, A Didangelos, A Luque, A Moncada-Pazos, A Noel, A Tan Ide, AC Jonsson-Rylander, AC Nicholson, AJ Fosang, B Joe, BH Koo, BH Koo, BV Nusgens, C Casal, C Esselens, C Gendron, C Kintakas, C Lopez-Otin, C Ricciardelli, CB Kern, CG Viloria, CH Mjaatvedt, CJ Liu, CJ Liu, CL Jacobi, CM Dancevic, CN Brocker, CR Flannery, D Wagsater, DL Russell, DL Silver, DR Edwards, DR McCulloch, DT Jones, Dylan R Edwards, EA Lin, EC Arner, ED Karagiannis, EM Majerus, F Guo, F Vazquez, FG Brunet, FX Gomis-Ruth, FX Gomis-Ruth, G Gao, G Gao, G Hashimoto, G Murphy, GC Choi, GE Lind, GG Levy, GJ Wayne, Grant N Wheeler, H Enomoto, H Jin, H Stanton, H Stanton, HL Lung, HM Brown, I Abbaszade, I Peluso, Ines Desanlis, J Dubail, J Dubail, J Felsenstein, J Hofsteenge, J Huxley-Jones, J Huxley-Jones, J Morales, JA Pyun, JC Adams, JC Rodriguez-Manzaneque, JC Rodriguez-Manzaneque, JC Rodriguez-Manzaneque, JD Sandy, JM Longpre, K Demircan, K Fujikawa, K Gopalakrishnan, K Kuno, K Kuno, K Stankunas, K Tamura, K Yamamoto, K Yamamoto, L Angerer, L Faivre, L Mittaz, L Mosyak, L Troeberg, L Troeberg, L Troeberg, L Wagstaff, LA Collins-Racie, LE Dupuis, LM Ricketts, M Cudic, M Hour El, M Kashiwagi, M Krampert, M Llamazares, MA Aldahmesh, MD Tortorella, MN Vankemmelbeke, N Dagoneau, N Hattori, N Rocks, N Rocks, N Stupka, NH Lim, NV Lee, NV Lee, P Wang, PH Lo, PJ Koshy, PS Chockalingam, R Kelwick, RC Salter, RH Song, Richard Kelwick, RL Robker, RP Somerville, RP Somerville, RS Patel, S Abdul-Majeed, S Gerhardt, S Kumar, S Kumar, S Nandadasa, S Porter, S Porter, SS Apte, SS Glasson, T Fontanil, T Shindo, TN Wight, U Auf Dem Keller, W Du, W Zeng, WE Kutz, WM Wang, X Lu, X Pu, XL Zheng, YJ Liu, YP Hsu   +145 more
core   +1 more source

MMP11 (matrix metalloproteinase 11 (stromelysin 3)) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on MMP11 (matrix metalloproteinase 11 (stromelysin 3)), with data on DNA, on the protein encoded, and where the gene is implicated.
P Basset, MC Rio
openaire   +1 more source

Matrix metalloproteinase 9 level as an indicator for restenosis following cervical and intracranial angioplasty and stenting

Neural Regeneration Research, 2015
Cervical and intracranial angioplasty and stenting is an effective and safe method of reducing the risk of ischemic stroke, but it may be affected by in-stent restenosis.
Jun-peng Liu, Yin-zhou Wang, Yong-kun Li, Qiong Cheng, Zheng Zheng   +4 more
doaj   +1 more source

Matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in diagnosis of pleural effusion of malignant origin [PDF]

, 2016
OBJECTIVES: The aim of the present study was to evaluate the diagnostic accuracy of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in differentiating benign from malignant exudative pleural effusions.
D'Angelo, L., Di Carlo, A., Di Domenico, M., Feola, A., Fiorelli, A., Mazzella, A., Ricci, S., Santini, M.   +7 more
core   +1 more source

Matrix Metalloproteinase-3 but Not Matrix Metalloproteinase-9, Implicated in the Manifestation of Chronic Periodontitis

Reports of Biochemistry and Molecular Biology, 2023
Periodontal disease is an inflammatory condition affecting the tooth's supporting tissues, resulting in gradual loss of periodontal ligament (PDL), alveolar bone, and gum resorption. Neutrophil and monocyte/macrophage, destructive proteases like matrix metalloproteinase (MMP)-3 and MMP-9 play pivotal roles in such lesions in periodontitis.
Pouyan, Razavi, Seyed Abdolrahim, Rezaee, Salehe, Akhondian, Nastaran, Asgari, Kazem, Fatemi, Farnaz, Mohajertehran   +5 more
openaire   +2 more sources

A Complete Expression Profile of Matrix-Degrading Metalloproteinases in Dupuytren’s Disease [PDF]

, 2007
Dupuytren’s disease (DD) is a common fibrotic condition of the palmar fascia, leading to deposition of collagen-rich cords and finger contractions. The metzincin superfamily contains key enzymes in the turnover of collagen and other extracellular matrix ...
Adrian J. Chojnowski, Baker, Baragi, Bird, Bisson, Bretz, Brinckerhoff, Brown, Bunker, Clark, Daniels, Drummond, d’Ortho, Graham P. Riley, Hutchinson, Ian M. Clark, Iredale, Jones, Jung, Kashiwagi, Kevorkian, Knauper, Le Goff, Luck, Mikkelsen, Mirastschijski, Moyer, Murphy, Nuttall, Ohuchi, Phillip Johnston, Porter, Porter, Price, Qian, Rayan, Rose K. Davidson, Schaer, Scott, Simon T. Donell, Smith, Tarlton, Tarpila, Thurston, Ulrich, Unemori, Unemori, Unemori, Williams   +48 more
core   +1 more source

Matrix metalloproteinase-3 in brain physiology and neurodegeneration [PDF]

Advances in Clinical and Experimental Medicine, 2019
Structural and functional synapse reorganization is one of the key issues of learning and memory mechanisms. Specific proteases, called matrix metalloproteinases (MMPs), play a pivotal role during learning-related modification of neural circuits. Different types of MMPs modify the extracellular perisynaptic environment, leading to the plastic changes ...
Anna Maria Lech, Grzegorz Wiera, Jerzy Władysław Mozrzymas   +2 more
openaire   +3 more sources