Results 61 to 70 of about 248,248 (311)

Neuroprotective Effects of Chlorogenic Acid in a Mouse Model of Intracerebral Hemorrhage Associated with Reduced Extracellular Matrix Metalloproteinase Inducer

Biomolecules, 2022
Chlorogenic acid (CGA) has been reported to have various biological activities, such as anti-inflammatory, anti-oxidant and anti-apoptosis effects.
Yang Liu, Fei Wang, Zhe Li, Yanling Mu, Voon Wee Yong, Mengzhou Xue   +5 more
doaj   +1 more source

Circulating levels of matrix proteases and their inhibitors in pregnant women with and without a history of recurrent pregnancy loss [PDF]

, 2010
Background: We have recently shown that serum relaxin-2 levels are attenuated in women with a history of recurrent pregnancy loss (RPL). We sought to determine whether a history of RPL is also associated with changes in serum matrix metalloproteases ...
Anumba, D.O.C., El Gelany, S., Elliott, S.L., Li, T.C.   +3 more
core   +3 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Gelatinases Increase in Bleomycin-induced Systemic Sclerosis Mouse Model

Iranian Journal of Allergy, Asthma and Immunology, 2019
Systemic sclerosis is a fibrotic autoimmune disease in which aberrant remodeling of the extracellular matrix in organs disturbs their functionalities.
Fateme Vafashoar, Kazem Mousavizadeh, Hadi Poormoghim, Abbas Tavasoli, Tahereh Musavi Shabestari, Sayed Ali Javadmoosavi, Nazanin Mojtabavi   +6 more
doaj   +1 more source

Contribution of Matrix Metalloproteinase-9 to Cerebral Edema and Functional Outcome following Experimental Subarachnoid Hemorrhage [PDF]

, 2011
Background: Cerebral edema is an important risk factor for death and poor outcome following subarachnoid hemorrhage (SAH). However, underlying mechanisms are still poorly understood.
Bauer AT, Broderick JP, Burggraf D, Claassen J, Clark AW, Doczi T, Dzwonek J, Feiler S, Fukuda S, Gasche Y, Guo Z, Jadhav V, Karsten Schöller, Mandal M, Mun-Bryce S, Nikolaus Plesnila, Rosenberg GA, Rosenberg GA, Rosenberg GA, Rosenberg GA, Schöller K, Sehba FA, Serge C. Thal, Sergej Feiler, Stanley JR, Stefan Zausinger, Thal SC, Vu TH, Wang X, Zausinger S   +29 more
core   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Matrix metalloproteinase-7 and matrix metalloproteinase-9 expression is upregulated in congenital lung malformations

The Turkish Journal of Pediatrics
Background. Congenital lung malformations (CLMs) refer to structural abnormalities of the lungs that occur during fetal development. Matrix metalloproteinases (MMPs) constitute a group of zinc-dependent enzymes, with certain members of this family ...
Ayşe Parlak, Seçil Ak Aksoy, Melis Erçelik, Çağla Tekin, Hülya Öztürk Nazlıoğlu, Berrin Tunca, Arif Nuri Gürpınar   +6 more
doaj   +1 more source

Assessment of the Relationship Between Matrix Metalloproteinase-9 Promoter Gene Polymorphism and Chronic Periodontitis

Pesquisa Brasileira em Odontopediatria e Clínica Integrada, 2021
Objective: To evaluate the association of MMP-9 promoter gene polymorphism in generalized chronic periodontitis patients of an Indian population.
Hiroj Bagde, Savitha Banakar, Alka Waghmare, Ashwini Bagde, Shailendra Singh Chaturvedi, Santosh Rayagouda Patil   +5 more
doaj  

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Evaluation of MMP‑2, MMP‑9, TIMP‑1, TIMP‑2, NGAL and MMP‑9/NGAL complex in urine and sera from patients with bladder cancer [PDF]

, 2015
The identification of biomarkers in urine or serum samples from patients with bladder cancer is urgently required for the development of non-invasive methods for the diagnosis of bladder carcinoma and to facilitate follow-up surveillance, to combat the ...
Bruzzese, Dario, DI CARLO, Angelina, Ricci, Serena   +2 more
core   +1 more source