Results 231 to 240 of about 116,965 (260)
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Matrix metalloproteinases and bone
Bone, 2008Matrix metalloproteinases (MMPs) are members of a family of zinc-dependent proteolytic enzymes. Several of the MMPs are expressed at high levels in bone and cartilage in mammals including humans and mice and are capable of cleaving native, undenatured collagens with long uninterrupted triple helices; these MMPs therefore potentially function as ...
Stephen M, Krane, Masaki, Inada
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Matrix metalloproteinases and angiogenesis
Current Opinion in Nephrology and Hypertension, 2002Angiogenesis is a prominent feature of numerous diseases, including cancer and arthritis, and appears to play an important role in kidney disease and hypertension. The matrix metalloproteinases, especially matrix metalloproteinase-2, play a vital role during angiogenesis by degrading the surrounding extracellular matrix and allowing endothelial cell ...
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Matrix Metalloproteinases and Their Inhibitors
2001Matrix metalloproteinases (MMPs) are a group of 16 enzymes that are capable of degrading extracellular matrix components. Their catalytic function is dependent on a zinc ion in the active center. MMPs are separated in three groups: gelatinases (type IV-collagenases), stromelysins, and interstitial collagenases.
A, Kugler, P, Thelen, R H, Ringert
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Matrix metalloproteinases in inflammation
Biochimica et Biophysica Acta (BBA) - General Subjects, 2014Matrix metalloproteinases (MMPs) are a family of ubiquitously expressed zinc-dependent endopeptidases with broad substrate specificity and strictly regulated tissue specific expression. They are expressed in physiological situations and pathological conditions involving inflammation.
Liisa, Nissinen, Veli-Matti, Kähäri
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The Roles of Matrix Metalloproteinases and Their Inhibitors in Human Diseases
International Journal of Molecular Sciences, 2020Claudia Castruita De La Rosa +2 more
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The Role of Matrix Metalloproteinases in Endometriosis: A Potential Target
Biomolecules, 2021Jiangfeng Ye, , Li Mingqing
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Structure and Function of Human Matrix Metalloproteinases
Cells, 2020Jorge Caldeira, Helena Laronha
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Matrix Metalloproteinases Shape the Tumor Microenvironment in Cancer Progression
International Journal of Molecular Sciences, 2022Johannes Eble +2 more
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Matrix Metalloproteinases Inhibitors in Cancer Treatment: An Updated Review (2013–2023)
Molecules, 2023Shriefa Almutairi, Sanaa Bardaweel
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