Results 41 to 50 of about 331,204 (356)
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018 Background Dilated cardiomyopathy (DCM) is a common cause of heart failure in adult and pediatric patients, but the underlying mechanism may vary in adults and children, with few studies conducted to date.
Sayantan Jana +7 more
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Matrix metalloproteinases and epileptogenesis [PDF]
Molecular and Cellular Pediatrics, 2014 Matrix metalloproteinases are vital drivers of synaptic remodeling in health and disease. It is suggested that at early stages of epileptogenesis, inhibition of matrix metalloproteinases may help ameliorate cell death, aberrant network rewiring, and neuroinflammation and prevent development of epilepsy.
openaire +3 more sources
Effect of beta-Dystroglycan Processing on Utrophin / DP116 Anchorage in Normal and MDX Mouse Schwann Cell Membrane [PDF]
Neuroscience 141 (18/04/2006) 607-620, 2007 In the peripheral nervous system, utrophin and the short dystrophin isoform (Dp116) are co-localized at the outermost layer of the myelin sheath of nerve fibers; together with the dystroglycan complex. In peripheral nerve, matrix metalloproteinase (MMP) creates a 30 kDa fragment of beta-dystroglycan, leading to a disruption of the link between the ...
arxiv +1 more source
Chemokine-induced secretion of gelatinase B in primary human monocytes [PDF]
, 2001 Chemokines help control normal leukocyte trafficking as well as their infiltration into tissues during acute and chronic inflammation. Matrix metalloproteinases (MMPs) help support the extravasation and infiltration of leukocytes through limited ...
Brew K. +7 more
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Zaporožskij Medicinskij Žurnal, 2014 Aim. Matrix metalloproteinases play a key role in adaptive postinfarction remodeling of the heart. In order to study the influence of anticoagulation therapy on the state of matrix metalloproteinases and their inhibitors, the incidence of post-infarction
S. M. Kyselov
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Liposomic lubricants suppress shear-stress induced inflammatory gene regulation in the joint in vivo [PDF]
arXiv, 2023 Osteoarthritis (OA) is a widespread, debilitating joint disease associated with articular cartilage degradation. It is driven via mechano-inflammatory catabolic pathways, presumed up-regulated due to increased shear stress on the cartilage-embedded chondrocytes, that lead to tissue degeneration.
arxiv
Association of circulating levels of MMP-8 with mortality from respiratory disease in patients with rheumatoid arthritis. [PDF]
, 2012 Matrix metalloproteinases (MMPs) are implicated in the destruction of the joint and have been shown to be strongly associated with inflammation in rheumatoid arthritis (RA).
Dawes, PT, Mattey, DL, Nixon, NB
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Matrix metalloproteinases in lung biology
Respiratory Research, 2000 Despite much information on their catalytic properties and gene regulation, we actually know very little of what matrix metalloproteinases (MMPs) do in tissues.
Parks William C, Shapiro Steven D
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Role of matrix metalloproteinase in the aneurismatic aortic disease
Monaldi Archives for Chest Disease, 2004 The aorta is involved in a large variety of diseases and the atherosclerotic aneurysms represent the most common type of these. Recent reports have attempted to clarify the mechanisms, that cause the formation and the progression of the atherosclerotic ...
Nicola Troisi +3 more
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Immunomodulatory role of metalloproteases in cancers: Current progress and future trends
Frontiers in Immunology, 2022 Metalloproteinases (MPs) is a large family of proteinases with metal ions in their active centers. According to the different domains metalloproteinases can be divided into a variety of subtypes mainly including Matrix Metalloproteinases (MMPs), A ...
Qi Wang +4 more
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