Results 31 to 40 of about 200,937 (295)
Osteoarticular complications of brucellosis: The diagnostic value and importance of detection matrix metalloproteinases [PDF]
Acta Medica Academica, 2015 Objectives. Matrix metalloproteinases (MMPs) has been implicated in the pathogenesis of infective, cancer and autoimmune diseases. In this study, we investigated the serum level of MMPs and its clinical importance in human brucellosis.
Maida Šiširak, Mirsada Hukić
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Chronic tendon pathology: molecular basis and therapeutic implications [PDF]
, 2005 Tendons are frequently affected by chronic pain or rupture. Many causative factors have been implicated in the pathology, which until relatively recently was under-researched and poorly understood.
Riley, GP
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Matrix metalloproteinases and their inhibitors
Фармакокинетика и Фармакодинамика, 2019 Metalloproteinase was discovered by Gross and Lapierre in 1962 for the first time. Since then, more than 20 enzymes of this family have been characterized, and their functions have been studied in detail.
O. S. Grigorkevich +2 more
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Chemokine-induced secretion of gelatinase B in primary human monocytes [PDF]
, 2001 Chemokines help control normal leukocyte trafficking as well as their infiltration into tissues during acute and chronic inflammation. Matrix metalloproteinases (MMPs) help support the extravasation and infiltration of leukocytes through limited ...
Brew K. +7 more
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Matrix Metalloproteinases and Glaucoma Treatment. [PDF]
, 2020 Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes that degrade extracellular matrix (ECM) components such as collagen and have important roles in multiple biological processes, including development and tissue remodeling, both in ...
Dibas, Mohammed +3 more
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Association of circulating levels of MMP-8 with mortality from respiratory disease in patients with rheumatoid arthritis. [PDF]
, 2012 Matrix metalloproteinases (MMPs) are implicated in the destruction of the joint and have been shown to be strongly associated with inflammation in rheumatoid arthritis (RA).
Dawes, PT, Mattey, DL, Nixon, NB
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Intravenous tPA therapy does not worsen acute intracerebral hemorrhage in mice [PDF]
, 2013 Tissue plasminogen activator (tPA) is the only FDA-approved treatment for reperfusing ischemic strokes. But widespread use of tPA is still limited by fears of inadvertently administering tPA in patients with intracerebral hemorrhage (ICH).
Arai, Ken +13 more
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Annals of Agricultural and Environmental Medicine, 2016 Introduction The prevalence of endometriosis among reproductive age women is 7–17%; however, these figures reach 20–50% in patients suffering from infertility. Matrix metalloproteinases (MMPs) activity is thought to be particularly essential in the early
Krzysztof Szymanowski +3 more
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Matrix Metalloproteinases [PDF]
Science's STKE, 2000 Matrix metalloproteinases (MMPs) contribute to cell migration and cell proliferation by degrading the extracellular matrix (ECM) and by releasing growth factors bound up in the ECM. The actions of MMPs are held in check by a class of proteins called tissue inhibitors of metalloproteinases (TIMPs).
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Functional relationship between matrix metalloproteinase‐11 and matrix metalloproteinase‐14 [PDF]
Cancer Medicine, 2014 AbstractMMP‐11 is a key factor in physiopathological tissue remodeling. As an active form is secreted, its activity must be tightly regulated to avoid detrimental effects. Although TIMP‐1 and TIMP‐2 reversibly inhibit MMP‐11, another more drastic scenario, presumably via hydrolysis, could be hypothesized.
Buache, Emilie +10 more
openaire +3 more sources