Results 11 to 20 of about 116,965 (260)

Matrix Metalloproteinases

Journal of Orofacial Sciences, 2010
Matrix metalloproteinases (MMPs), also known as matrixins, belong to a group of zinc-dependent proteins, which are thought to play a central role in the breakdown of extracellular matrix. Collagen, elastin, gelatin and casein are major components cleaved by MMPs.
S Sahitya, Babitha Nugala, B B Santosh Kumar   +2 more
doaj   +5 more sources

Matrix Metalloproteinases and Glaucoma

Biomolecules, 2022
Matrix metalloproteinases (MMPs) are enzymes that decompose extracellular matrix (ECM) proteins. MMPs are thought to play important roles in cellular processes, such as cell proliferation, differentiation, angiogenesis, migration, apoptosis, and host ...
Moo Hyun Kim, Su-Ho Lim
doaj   +3 more sources

Challenges in Matrix Metalloproteinases Inhibition

Biomolecules, 2020
Matrix metalloproteinases are enzymes that degrade the extracellular matrix. They have different substrates but similar structural organization. Matrix metalloproteinases are involved in many physiological and pathological processes and there is a need ...
Helena Laronha, Inês Carpinteiro, Jaime Portugal, Ana Azul, Mário Polido, Krasimira T. Petrova, Madalena Salema-Oom, Jorge Caldeira   +7 more
doaj   +3 more sources

Polymerizable Matrix Metalloproteinases’ Inhibitors with Potential Application for Dental Restorations

Biomedicines, 2021
Collagen cleavage by matrix metalloproteinase (MMP) is considered a major cause of dental resins long term failure. Most MMP inhibitors display significant toxicity and are unsuitable for dental resins’ applications. Here we report a study of a new class
Helena Laronha, Inês Carpinteiro, Jaime Portugal, Ana Azul, Mário Polido, Krasimira T. Petrova, Madalena Salema-Oom, Isabel Barahona, Jorge Caldeira   +8 more
doaj   +1 more source

Matrix metalloproteinases-9 and tissue inhibitor of matrix metalloproteinases-1 in sarcoidosis patients [PDF]

Arhiv za farmaciju, 2017
Matrix metaloproteinases (MMPs) and their specific inhibitors - tissue inhibitors of matrix metalloproteinases (TIMPs) play an important role in pulmonary extracellular matrix destruction. Sarcoidosis is an inflammatory disease affecting multiple organs.
Ivanišević Jasmina, Stefanović Aleksandra, Kotur-Stevuljević Jelena, Jelić-Ivanović Zorana, Spasić Slavica, Videnović-Ivanov Jelica, Mihailović-Vučinić Violeta   +6 more
doaj   +1 more source

Extracellular Matrix Enzymes and Immune Cell Biology

Frontiers in Molecular Biosciences, 2021
Remodelling of the extracellular matrix (ECM) by ECM metalloproteinases is increasingly being associated with regulation of immune cell function. ECM metalloproteinases, including Matrix Metalloproteinases (MMPs), A Disintegrin and Metalloproteinases ...
Meagan McMahon, Siying Ye, Jess Pedrina, Daniel Dlugolenski, John Stambas   +4 more
doaj   +1 more source

Matrix Metalloproteinases in Predicting Nonproliferative Diabetic Retinopathy in Old Age

Oftalʹmologiâ, 2023
The development of diabetic retinopathy is associated with matrix metalloproteinases, but they are rarely used to predict this pathology. The purpose of the study is to predict the development of nonproliferative diabetic retinopathy in old age based on ...
O. L. Fabikantov, I. V. Lev, N. M. Agarkov, R. E. Osmanov   +3 more
doaj   +1 more source

Matrix Metalloproteinases

Journal of UOEH, 1997
Matrix-degrading enzymes, matrix metalloproteinases, are members of a unique family of Zinc-binding endopeptidases that are responsible for the metabolism of extracellular components in the tissue stroma. Their controlled expression is essential for normal processes such as wound healing and tissue remodeling, including embryogenesis.
Parsons, S. L., Watson, S. A., Brown, P. D., Collins, H. M., Steele, R. J. C.   +4 more
openaire   +6 more sources

The relationship between the first episode of wheezing and matrix metalloproteinases-9 and MMP-2 and tissue inhibitors of MMP-1 levels in preterm infants

Annals of Thoracic Medicine, 2013
Aims: Matrix metalloproteinases (MMP) have been associated with neonatal lung morbidity and MMP dysregulation contributes to the pathology of chronic and acute lung disorders.
Rabia Gonul Sezer, Gokhan Aydemir, Abdulkadir Bozaykut, Serdar Hira, Ilhan Asya Tanju, Ömer Özcan   +5 more
doaj   +1 more source

MT4-MMP deficiency increases patrolling monocyte recruitment to early lesions and accelerates atherosclerosis

Nature Communications, 2018
Matrix metalloproteinases (MMP) are involved in vascular remodeling associated with plaque progression. Little is known about their immune regulatory role in vascular disorders.
Cristina Clemente, Cristina Rius, Laura Alonso-Herranz, Mara Martín-Alonso, Ángela Pollán, Emilio Camafeita, Fernando Martínez, Rubén A. Mota, Vanessa Núñez, Cristina Rodríguez, Motoharu Seiki, José Martínez-González, Vicente Andrés, Mercedes Ricote, Alicia G. Arroyo   +14 more
doaj   +1 more source