Results 11 to 20 of about 116,728 (258)

Matrix metalloproteinases in COVID-19: underlying significance

open access: yesBiotechnology & Biotechnological Equipment, 2023
The role of matrix metalloproteinases (MMPs) in pathogenesis and severity of coronavirus disease 2019 (COVID-19) is under extensive exploration. MMPs are a family of extracellular proteases involved in a variety of physiological and pathological ...
Usman Khalid   +2 more
doaj   +1 more source

MT4-MMP deficiency increases patrolling monocyte recruitment to early lesions and accelerates atherosclerosis

open access: yesNature Communications, 2018
Matrix metalloproteinases (MMP) are involved in vascular remodeling associated with plaque progression. Little is known about their immune regulatory role in vascular disorders.
Cristina Clemente   +14 more
doaj   +1 more source

The relationship between the first episode of wheezing and matrix metalloproteinases-9 and MMP-2 and tissue inhibitors of MMP-1 levels in preterm infants

open access: yesAnnals of Thoracic Medicine, 2013
Aims: Matrix metalloproteinases (MMP) have been associated with neonatal lung morbidity and MMP dysregulation contributes to the pathology of chronic and acute lung disorders.
Rabia Gonul Sezer   +5 more
doaj   +1 more source

Role of matrix Metalloproteinases in pituitary adenoma invasion

open access: yesChinese Neurosurgical Journal, 2018
Though pituitary adenomas are benign tumors in most cases, a considerable fraction of PAs behave in a malignant-like manner and invade to the adjacent structures in sellar region, especially the cavernous sinuses.
Chengxian Yang, Xinjie Bao, Renzhi Wang
doaj   +1 more source

Plasma matrix metalloproteinases in neonates having surgery for congenital heart disease

open access: yesHeart International, 2009
During cardiopulmonary-bypass matrix-metalloproteinases released may contribute to ventricular dysfunction. This study was to determine plasma matrix-metalloproteinases in neonates after cardiopulmonary-bypass and their relation to post-operative course.
David B. Ross   +7 more
doaj   +1 more source

Matrix metalloproteinases and their inhibitors

open access: yesФармакокинетика и Фармакодинамика, 2019
Metalloproteinase was discovered by Gross and Lapierre in 1962 for the first time. Since then, more than 20 enzymes of this family have been characterized, and their functions have been studied in detail.
O. S. Grigorkevich   +2 more
doaj   +1 more source

Matrix metalloproteinases and epileptogenesis [PDF]

open access: yesMolecular and Cellular Pediatrics, 2014
Matrix metalloproteinases are vital drivers of synaptic remodeling in health and disease. It is suggested that at early stages of epileptogenesis, inhibition of matrix metalloproteinases may help ameliorate cell death, aberrant network rewiring, and neuroinflammation and prevent development of epilepsy.
openaire   +2 more sources

Matrix metalloproteinase-2 (MMP-2), MMP-9, tissue inhibitor of matrix metalloproteinases (TIMP-1) and transforming growth factor-β2 (TGF-β2) expression in eutopic endometrium of women with peritoneal endometriosis

open access: yesAnnals of Agricultural and Environmental Medicine, 2016
Introduction The prevalence of endometriosis among reproductive age women is 7–17%; however, these figures reach 20–50% in patients suffering from infertility. Matrix metalloproteinases (MMPs) activity is thought to be particularly essential in the early
Krzysztof Szymanowski   +3 more
doaj   +1 more source

Matrix metalloproteinases in skin [PDF]

open access: yesExperimental Dermatology, 1997
Abstract Matrix metalloproteinases (MMPs) are a family of zinc‐dependent endopeptidases collectively capable of degrading essentially all extracellular matrix components. These enzymes can be produced by several different types of cells in skin such as fibroblasts, keratinocytes.
V M, Kähäri, U, Saarialho-Kere
openaire   +2 more sources

Matrix metalloproteinases in lung biology

open access: yesRespiratory Research, 2000
Despite much information on their catalytic properties and gene regulation, we actually know very little of what matrix metalloproteinases (MMPs) do in tissues.
Parks William C, Shapiro Steven D
doaj   +1 more source

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