Results 41 to 50 of about 200,937 (295)
Differential expression of ADAMTS -1, -4, -5 and TIMP -3 in rat spinal cord at different stages of acute experimental autoimmune encephalomyelitis [PDF]
, 2005 Experimental autoimmune encephalomyelitis (EAE) is an animal model of inflammatory demyelination, a pathological event common to multiple sclerosis (MS). During CNS inflammation there are alterations in the extracellular matrix (ECM).
A.K. Cross +52 more
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Matrix metalloproteinases in lung biology
Respiratory Research, 2000 Despite much information on their catalytic properties and gene regulation, we actually know very little of what matrix metalloproteinases (MMPs) do in tissues.
Parks William C, Shapiro Steven D
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Zaporožskij Medicinskij Žurnal, 2014 Aim. Matrix metalloproteinases play a key role in adaptive postinfarction remodeling of the heart. In order to study the influence of anticoagulation therapy on the state of matrix metalloproteinases and their inhibitors, the incidence of post-infarction
S. M. Kyselov
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Thermal stability of human matrix metalloproteinases
Heliyon, 2020 Matrix metalloproteinases (MMP) are key players in the remodelling of the extracellular matrix under physiological and pathological conditions. Thermodynamic parameters of human recombinant metalloproteinases of the active (rMMP2, 3, 7, 8 and 9) and ...
Noemi Meraz-Cruz +3 more
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MMP2 and MMP9 contribute to lung ischemia–reperfusion injury via promoting pyroptosis in mice
BMC Pulmonary Medicine, 2022 Background Lung ischemia–reperfusion injury (LIRI) is a cause of poor prognosis in several lung diseases and after lung transplantation. In LIRI, matrix metalloproteinases and pyroptosis indicators change in parallel, both of them involvement of ...
Peng Zhou +4 more
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Targeting matrix metalloproteinase MMP3 greatly enhances oncolytic virus mediated tumor therapy
Translational Oncology, 2021 In cancer, the extracellular matrix is extensively remodeled during chronic inflammation, thus affecting cell transcription, differentiation, migration and cell-cell interactions.
Minglong Liang +8 more
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Inhibitory antibodies designed for matrix metalloproteinase modulation [PDF]
, 2019 The family of matrix metalloproteinases (MMPs) consists of a set of biological targets that are involved in a multitude of severe pathogenic events such as different forms of cancers or arthritis.
Fischer, Thomas, Riedl, Rainer
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Role of matrix metalloproteinase in the aneurismatic aortic disease
Monaldi Archives for Chest Disease, 2004 The aorta is involved in a large variety of diseases and the atherosclerotic aneurysms represent the most common type of these. Recent reports have attempted to clarify the mechanisms, that cause the formation and the progression of the atherosclerotic ...
Nicola Troisi +3 more
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Matrix Metalloproteinases in Health and Disease
Biomolecules, 2020 Matrix metalloproteinases (MMPs) are members of an enzyme family and, under normal physiological conditions, are critical for maintaining tissue allostasis [...]
Raffaele Serra
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Immunomodulatory role of metalloproteases in cancers: Current progress and future trends
Frontiers in Immunology, 2022 Metalloproteinases (MPs) is a large family of proteinases with metal ions in their active centers. According to the different domains metalloproteinases can be divided into a variety of subtypes mainly including Matrix Metalloproteinases (MMPs), A ...
Qi Wang +4 more
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