Crotalus atrox venom preconditioning increases plasma fibrinogen and reduces perioperative hemorrhage in a rat model of surgical brain injury. [PDF]
, 2017 Perioperative bleeding is a potentially devastating complication in neurosurgical patients, and plasma fibrinogen concentration has been identified as a potential modifiable risk factor for perioperative bleeding.
Applegate, Richard +12 more
core +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018 Background Dilated cardiomyopathy (DCM) is a common cause of heart failure in adult and pediatric patients, but the underlying mechanism may vary in adults and children, with few studies conducted to date.
Sayantan Jana +7 more
doaj +1 more source
The possibilities of using the inhibitors of matrix metalloproteinases for keratoplasty
Трансплантология (Москва), 2023 Introduction. The review is devoted to the actual problem of treating patients with keratolysis. The role of matrix metalloproteinases in the pathogenesis of cornea and corneal graft melting is discussed as well as the practical experience of using ...
K. V. Sirotkina, E. V. Chentsova
doaj +1 more source
Implications of MMP9 for Blood Brain Barrier Disruption and Hemorrhagic Transformation Following Ischemic Stroke. [PDF]
, 2016 Numerous studies have documented increases in matrix metalloproteinases (MMPs), specifically MMP-9 levels following stroke, with such perturbations associated with disruption of the blood brain barrier (BBB), increased risk of hemorrhagic complications ...
Adibhatla +133 more
core +3 more sources
Biology, 2023 Matrix metalloproteinases (MMPs) are a group of proteolytic enzymes which are members of the zinc endopeptidase family. They have the ability to degrade extracellular matrix elements, allowing for the release of binding molecules and cell migration ...
Katarzyna Jadczyk-Sorek +4 more
doaj +1 more source
Action of the Metalloproteinases in Gonadal Remodeling during Sex Reversal in the Sequential Hermaphroditism of the Teleostei Fish Synbranchus marmoratus (Synbranchiformes: Synbranchidae) [PDF]
, 2018 Teleostei present great plasticity regarding sex change. During sex reversal, the whole gonadincluding the germinal epithelium undergoes significant changes, remodeling, and neoformation.However, there is no information on the changes that occur within ...
Antoneli, Fernanda +3 more
core +2 more sources
Multifaceted role of Matrix Metalloproteinases (MMPs)
Frontiers in Molecular Biosciences, 2015 Matrix metalloproteinases (MMPs), a large family of calcium-dependent zinc-containing endopeptidases, are involved the tissue remodeling and degradation of the extracellular matrix.
Divya eSingh +3 more
doaj +1 more source
Anti-MMP-2 and MMP-9 activity of Salsola komarovii Iljin extract and its solvent fractions
Asian Pacific Journal of Tropical Biomedicine, 2020 Objective: To investigate matrix metalloproteinases (MMP)-2 and MMP-9 inhibitory effect of Salsola komarovii Iljin, an edible halophyte with health beneficial effects. Methods: Salsola komarovii crude extracts (SKI), and solvent (n-hexane, 85% aq.
Jung-Ha Kil +8 more
doaj +1 more source
Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells [PDF]
, 2007 MMP-9 (matrix metalloproteinase 9) plays a critical role in tumour progression. Although the biochemical properties of the secreted form of proMMP-9 are well characterized, little is known about the function and activity of cell surface-associated proMMP-
Egea, Virginia +6 more
core +1 more source
Are matrix metalloproteinases the missing link? [PDF]
Invertebrate Survival Journal, 2005 It is more and more evident that the matrix metalloproteinase (MMP) system is not a characteristicfeature of vertebrate animals only, as it can also be found in many invertebrate organisms. Thisendopeptidase family has been widely studied since its first
F Mannello, G Tonti, S Papa
doaj +2 more sources