Results 51 to 60 of about 116,728 (258)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Matrix Metalloproteinases in Health and Disease 2.0

Biomolecules, 2022
Matrix metalloproteinases (MMPs) are members of an enzyme family that are critical for maintaining tissue allostasis [...]
Raffaele Serra
doaj   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Combining Three Peripheral Blood Biomarkers to Stratify Rheumatoid Arthritis–Associated Interstitial Lung Disease Risk

Arthritis Care &Research, EarlyView.
Objective The purpose was to evaluate a biomarker score consisting of MUC5B rs35705950 promoter variant, plasma matrix metalloproteinase‐7 (MMP‐7), and serum anti–malondialdehyde‐acetaldehyde (anti‐MAA) antibody for rheumatoid arthritis (RA)–associated interstitial lung disease (ILD) risk stratification.
Kelsey Coziahr, Austin M. Wheeler, Brent A. Luedders, Michael Duryee, Halie Frideres, Katherine D. Wysham, Grant W. Cannon, Gary Kunkel, Dana P. Ascherman, Paul A. Monach, Gail S. Kerr, Andreas M. Reimold, Scott M. Matson, Joshua F. Baker, Geoffrey M. Thiele, Ted R. Mikuls, Bryant R. England   +16 more
wiley   +1 more source

Matrix metalloproteinases in tuberculosis [PDF]

European Respiratory Journal, 2011
Tuberculosis (TB) remains a global health pandemic. Infection is spread by the aerosol route andMycobacterium tuberculosismust drive lung destruction to be transmitted to new hosts. Such inflammatory tissue damage is responsible for morbidity and mortality in patients.
Elkington, P. T., Ugarte-Gil, C. A., Friedland, J. S.   +2 more
openaire   +3 more sources

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

The effects of smoking on the expression of gelatinases in chronic periodontitis: a cross-sectional study

Brazilian Oral Research, 2018
Smokers have a risk of developing periodontal disease. Matrix metalloproteinases (MMP) play a significant role in periodontal tissue destruction. In this study possible relationship between smoking and gingival tissue expression of gelatinases in chronic
Rahşan Atasoy ŞENTÜRK, Yasemin SEZGİN, Şule BULUT, Binnaz Handan ÖZDEMIR   +3 more
doaj   +1 more source

Production of factors involved into fibrosis regulation by various types of human macrophages

Медицинская иммунология, 2020
Macrophages (Mφ) play a key role in regulation of fibrogenesis, including proliferation of fibroblasts and  myofibroblasts, differentiation of progenitor cells into  myofibroblasts, as well as synthesis  and  secretion of the  extracellular matrix ...
A. A. Maksimova, E. Ya. Shevela, L. V. Sakhno, A. A. Ostanin, E. R. Chernykh   +4 more
doaj   +1 more source

Matrix metalloproteinases and atherosclerosis

Postępy Higieny i Medycyny Doświadczalnej, 2011
Matrix metalloproteinases (MMPs), a family of proteolytic enzymes that degrade extracellular matrix (ECM), seem to have an important role in pathogenesis of atherosclerosis. Released by inflammatory cells and smooth muscle cells, MMPs regulate the vascular remodeling process.
Piotr, Fic, Izabela, Zakrocka, Jacek, Kurzepa, Andrzej, Stepulak   +3 more
openaire   +2 more sources

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source