Results 21 to 30 of about 116,728 (258)
Zaporožskij Medicinskij Žurnal, 2014 Aim. Matrix metalloproteinases play a key role in adaptive postinfarction remodeling of the heart. In order to study the influence of anticoagulation therapy on the state of matrix metalloproteinases and their inhibitors, the incidence of post-infarction
S. M. Kyselov
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Thermal stability of human matrix metalloproteinases
Heliyon, 2020 Matrix metalloproteinases (MMP) are key players in the remodelling of the extracellular matrix under physiological and pathological conditions. Thermodynamic parameters of human recombinant metalloproteinases of the active (rMMP2, 3, 7, 8 and 9) and ...
Noemi Meraz-Cruz +3 more
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MMP2 and MMP9 contribute to lung ischemia–reperfusion injury via promoting pyroptosis in mice
BMC Pulmonary Medicine, 2022 Background Lung ischemia–reperfusion injury (LIRI) is a cause of poor prognosis in several lung diseases and after lung transplantation. In LIRI, matrix metalloproteinases and pyroptosis indicators change in parallel, both of them involvement of ...
Peng Zhou +4 more
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Targeting matrix metalloproteinase MMP3 greatly enhances oncolytic virus mediated tumor therapy
Translational Oncology, 2021 In cancer, the extracellular matrix is extensively remodeled during chronic inflammation, thus affecting cell transcription, differentiation, migration and cell-cell interactions.
Minglong Liang +8 more
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Matrix metalloproteinases at a glance [PDF]
Journal of Cell Science, 2004 The matrix metalloproteinases (MMPs) are one of the major families of proteinases that play key roles in the responses of cells to their microenvironment. Most notably the MMPs have the combined capacity to degrade all the components of the extracellular matrix.
Meng-Huee, Lee, Gillian, Murphy
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Role of matrix metalloproteinase in the aneurismatic aortic disease
Monaldi Archives for Chest Disease, 2004 The aorta is involved in a large variety of diseases and the atherosclerotic aneurysms represent the most common type of these. Recent reports have attempted to clarify the mechanisms, that cause the formation and the progression of the atherosclerotic ...
Nicola Troisi +3 more
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Matrix Metalloproteinases in Health and Disease
Biomolecules, 2020 Matrix metalloproteinases (MMPs) are members of an enzyme family and, under normal physiological conditions, are critical for maintaining tissue allostasis [...]
Raffaele Serra
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Immunomodulatory role of metalloproteases in cancers: Current progress and future trends
Frontiers in Immunology, 2022 Metalloproteinases (MPs) is a large family of proteinases with metal ions in their active centers. According to the different domains metalloproteinases can be divided into a variety of subtypes mainly including Matrix Metalloproteinases (MMPs), A ...
Qi Wang +4 more
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Matrix metalloproteinases in emphysema [PDF]
Matrix Biology, 2018 Several studies have implicated a causative role for specific matrix metalloproteinases (MMPs) in the development and progression of cigarette smoke-induced chronic obstructive pulmonary disease (COPD) and its severe sequela, emphysema. However, the precise function of any given MMP in emphysema remains an unanswered question.
Sina A, Gharib +2 more
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018 Background Dilated cardiomyopathy (DCM) is a common cause of heart failure in adult and pediatric patients, but the underlying mechanism may vary in adults and children, with few studies conducted to date.
Sayantan Jana +7 more
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