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Matrix metalloproteinases in COVID-19: underlying significance
The role of matrix metalloproteinases (MMPs) in pathogenesis and severity of coronavirus disease 2019 (COVID-19) is under extensive exploration. MMPs are a family of extracellular proteases involved in a variety of physiological and pathological ...
Usman Khalid +2 more
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Role of matrix Metalloproteinases in pituitary adenoma invasion
Though pituitary adenomas are benign tumors in most cases, a considerable fraction of PAs behave in a malignant-like manner and invade to the adjacent structures in sellar region, especially the cavernous sinuses.
Chengxian Yang, Xinjie Bao, Renzhi Wang
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Plasma matrix metalloproteinases in neonates having surgery for congenital heart disease
During cardiopulmonary-bypass matrix-metalloproteinases released may contribute to ventricular dysfunction. This study was to determine plasma matrix-metalloproteinases in neonates after cardiopulmonary-bypass and their relation to post-operative course.
David B. Ross +7 more
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Dentin adhesion and matrix metalloproteinases
One of the challenges of contemporary conservative dentistry is prevention of secondary caries. Despite the growing bond strength values, which is obtained by chemical and technical improvements, rapid solubility and low durability still make a problem.
Renata Chałas, Olga Rudzka
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Matrix metalloproteinases and their inhibitors
Metalloproteinase was discovered by Gross and Lapierre in 1962 for the first time. Since then, more than 20 enzymes of this family have been characterized, and their functions have been studied in detail.
O. S. Grigorkevich +2 more
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Osteoarticular complications of brucellosis: The diagnostic value and importance of detection matrix metalloproteinases [PDF]
Objectives. Matrix metalloproteinases (MMPs) has been implicated in the pathogenesis of infective, cancer and autoimmune diseases. In this study, we investigated the serum level of MMPs and its clinical importance in human brucellosis.
Maida Šiširak, Mirsada Hukić
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Matrix metalloproteinases and epileptogenesis [PDF]
Matrix metalloproteinases are vital drivers of synaptic remodeling in health and disease. It is suggested that at early stages of epileptogenesis, inhibition of matrix metalloproteinases may help ameliorate cell death, aberrant network rewiring, and neuroinflammation and prevent development of epilepsy.
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Matrix metalloproteinases in skin [PDF]
Abstract Matrix metalloproteinases (MMPs) are a family of zinc‐dependent endopeptidases collectively capable of degrading essentially all extracellular matrix components. These enzymes can be produced by several different types of cells in skin such as fibroblasts, keratinocytes.
V M, Kähäri, U, Saarialho-Kere
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Introduction The prevalence of endometriosis among reproductive age women is 7–17%; however, these figures reach 20–50% in patients suffering from infertility. Matrix metalloproteinases (MMPs) activity is thought to be particularly essential in the early
Krzysztof Szymanowski +3 more
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Matrix metalloproteinases at a glance [PDF]
The matrix metalloproteinases (MMPs) are one of the major families of proteinases that play key roles in the responses of cells to their microenvironment. Most notably the MMPs have the combined capacity to degrade all the components of the extracellular matrix.
Meng-Huee, Lee, Gillian, Murphy
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