Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Length at maturity in three pelagic sharks (Lamna nasus, Isurus oxyrinchus, and Prionace glauca) from New Zealand [PDF]
, 2005 Reproductive data collected from porbeagle, shortfin mako, and blue sharks caught around New Zealand were used to estimate the median length at maturity.
Duffy, Clinton, Francis, Malcolm P.
core
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Host microbiota constantly control maturation and function of microglia in the CNS
Nature Neuroscience, 2015 Daniel Erny +19 more
semanticscholar +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Remotely sensing wheat maturation with radar [PDF]
The scattering properties of wheat were studied in the 8-18 GHz band as a function of frequency, polarization, incidence angle, and crop maturity. Supporting ground truth was collected at the time of measurement.
Bush, T. F., Ulaby, F. T.
core +1 more source
Hydraulic Modelling and Optimization of a Wastewater Treatment System for Developing Nations Using Computational Fluid Dynamics [PDF]
, 2012 Waste stabilization pond (WSP) is globally one of the most popular wastewater treatment options because of its high efficiency and low cost. However, no rigorous assessment of WSPs that account for cost in addition to hydrodynamics and treatment ...
Adekalu, K.O. +2 more
core
Osthole treatment ameliorates Th2-mediated allergic asthma and exerts immunomodulatory effects on dendritic cell maturation and function [PDF]
, 2017 Chen‐Yuan Chiang +5 more
openalex +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source