Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
The relationship between maternal glucose concentrations, gestational diabetes mellitus, placental weight, and placental vascular malperfusion lesions: A retrospective study of a U.S. pregnancy cohort. [PDF]
Arcot A +3 more
europepmc +1 more source
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan +6 more
wiley +1 more source
Impact of Nutrition on Embryo Production in Cattle: Mechanistic Insights. [PDF]
Kasimanickam R, Kasimanickam V.
europepmc +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Can classification strategies improve automated cervical vertebral maturation staging? A comparative study. [PDF]
Lee SY, Ryu J, Kim YH, Lee YS, Jung SK.
europepmc +1 more source
Carboxyl-Terminal Region of the Maturation Protein of RNA Coliphage Qβ Mediates Host Attachment, Virion Formation, and Cell Lysis. [PDF]
Kajitani M, Hakoshima N, Inokuchi Y.
europepmc +1 more source
The Effects of Maturation and Dyslexia Risk on Neural Speech-Sound Encoding and Discrimination at Preschool Stage. [PDF]
Navarrete-Arroyo S +3 more
europepmc +1 more source
Manipulating root-associated microbiomes to boost drought resistance in dryland winter wheat with Streptomyces pactum Act12. [PDF]
Li M +8 more
europepmc +1 more source

