Results 81 to 90 of about 131,547 (273)

Redefining Dendritic Cell Vaccines: Synergistically Co‐priming DC and B Cells With Nanoparticles Loading Whole Cell Antigens Maximizes the Efficacy of DC Vaccines

open access: yesAdvanced Science, EarlyView.
Dendritic cells (DC) vaccine is an important type of vaccines. However, the limited efficacy of DC vaccines hinders their widely application. This study redefines DC vaccines and provides a new DC‐BC vaccine that have much better therapeutic efficacy.
Xiangxiang Xu   +11 more
wiley   +1 more source

Decentralized MPC based Obstacle Avoidance for Multi-Robot Target Tracking Scenarios

open access: yes, 2018
In this work, we consider the problem of decentralized multi-robot target tracking and obstacle avoidance in dynamic environments. Each robot executes a local motion planning algorithm which is based on model predictive control (MPC).
Ahmad, Aamir   +4 more
core   +1 more source

Fault-tolerant formation driving mechanism designed for heterogeneous MAVs-UGVs groups [PDF]

open access: yes, 2013
A fault-tolerant method for stabilization and navigation of 3D heterogeneous formations is proposed in this paper. The presented Model Predictive Control (MPC) based approach enables to deploy compact formations of closely cooperating autonomous aerial ...
A Abdessameud   +29 more
core   +1 more source

A dsRNA Viral Transcriptional Regulator Evades Innate Immunity by Hijacking Host CoTranscription Factor DHX9

open access: yesAdvanced Science, EarlyView.
This study identifies a new viral mechanism by a viral protein σ3 that functions as a vTR to suppress NF‐κB gene expression via its direct interaction with the host helicase DHX9. Through their interaction, σ3 not only impairs the initial recruitment of Pol II but also affects Pol II pause‐release and ultimately suppresses NF‐κB gene expression ...
Xueyang Pang   +12 more
wiley   +1 more source

Desain Kontrol Altitude Hold Pada Miniature Aerial Vehicle (MAV) [PDF]

open access: yes, 2010
Teknologi wahana terbang tanpa awak atau lebih dikenal dengan istilah unmanned aerial vehicle (UAV) beberapa dekade belakangan ini telah menarik banyak peneliti untuk pengembangannya. Melihat minimnya penelitian yang dilakukan berkaiatan dengan topik ini
Bima Sena Bayu, Bima
core  

Methods to Visualize MAVS Subcellular Localization [PDF]

open access: yes, 2017
The mitochondrial antiviral signaling (MAVS) protein is a central adaptor protein required for antiviral innate immune signaling. To facilitate its roles in innate immunity, MAVS localizes to multiple intracellular membranous compartments, including the mitochondria, the mitochondrial-associated ER membrane (MAM), and peroxisomes.
Christine, Vazquez   +2 more
openaire   +2 more sources

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

open access: yesAdvanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan   +11 more
wiley   +1 more source

J-MOD$^{2}$: Joint Monocular Obstacle Detection and Depth Estimation

open access: yes, 2017
In this work, we propose an end-to-end deep architecture that jointly learns to detect obstacles and estimate their depth for MAV flight applications.
Ciarfuglia, Thomas A.   +3 more
core   +1 more source

A lightweight autonomous MAV for indoor search and rescue

open access: yesAsian journal of control, 2019
Micro Aerial Vehicles (MAVs) have great potentials to be applied for indoor search and rescue missions. In this paper, we propose a modular lightweight design of an autonomous MAV with integrated hardware and software.
Yingcai Bi   +4 more
semanticscholar   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu   +6 more
wiley   +1 more source

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