Results 51 to 60 of about 4,636,575 (354)
Combining experiments and simulations using the maximum entropy principle. [PDF]
PLoS Computational Biology, 2014 A key component of computational biology is to compare the results of computer modelling with experimental measurements. Despite substantial progress in the models and algorithms used in many areas of computational biology, such comparisons sometimes ...
Wouter Boomsma +2 more
doaj +1 more source
Mean-Field Pontryagin Maximum Principle [PDF]
Journal of Optimization Theory and Applications, 2015 We derive a maximum principle for optimal control problems with constraints given by the coupling of a system of ordinary differential equations and a partial differential equation of Vlasov type with smooth interaction kernel.
M. Bongini +3 more
semanticscholar +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
The Maximum Entropy Production Principle and Linear Irreversible Processes
Entropy, 2010 It is shown that Onsager’s principle of the least dissipation of energy is equivalent to the maximum entropy production principle. It is known that solutions of the linearized Boltzmann equation make extrema of entropy production.
Milan Brumen +5 more
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Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Venus atmosphere profile from a maximum entropy principle [PDF]
Nonlinear Processes in Geophysics, 2007 The variational method with constraints recently developed by Verkley and Gerkema to describe maximum-entropy atmospheric profiles is generalized to ideal gases but with temperature-dependent specific heats.
L. N. Epele +4 more
doaj
Maximum Configuration Principle for Driven Systems with Arbitrary Driving
Entropy, 2018 Depending on context, the term entropy is used for a thermodynamic quantity, a measure of available choice, a quantity to measure information, or, in the context of statistical inference, a maximum configuration predictor.
Rudolf Hanel, Stefan Thurner
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Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins
FEBS Open Bio, EarlyView.We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó +7 more
wiley +1 more source
Stochastic global maximum principle for optimization with recursive utilities
, 2017 In this paper, we study the recursive stochastic optimal control problems. The control domain does not need to be convex, and the generator of the backward stochastic differential equation can contain z.
Mingshang Hu
semanticscholar +1 more source