Results 51 to 60 of about 6,326,277 (372)

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Application of maximum principle optimizing active current subharmonic filter [PDF]

Омский научный вестник, 2019
In this article, the structure and parameters of an optimal regulator for active filter current subharmonics (AFSC) are received based on the optimal control method L. S. Pontryagin.
V. N. Anosov, D. N. Belkova, V. M. Kaveshnikov   +2 more
doaj   +1 more source

Maximum Principles at infinity

Journal of Differential Geometry, 2008
We prove a general maximum principle at infinity for properly immersed minimal surfaces with boundary in R 3 . An important corollary of this maximum principle at infinity is the existence of a fixed sized regular neighborhood for any properly embedded minimal surface of bounded curvature.
Meeks, WH, Rosenberg, H
openaire   +3 more sources

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Perron-Frobenius, principal eigenvalue, Maximum Principle: a personal itinerary [PDF]

Rendiconti di Matematica e delle Sue Applicazioni, 2020
This paper dedicated to Umberto Mosco revisits a line of my research starting in the early 70's in the aim of identifying a path connecting different concepts which play a role in elliptic pde's, spectral theory and optimal control.
Italo Capuzzo Dolcetta
doaj  

Mutation-Selection Balance: Ancestry, Load, and Maximum Principle

, 2002
We show how concepts from statistical physics, such as order parameter, thermodynamic limit, and quantum phase transition, translate into biological concepts in mutation-selection models for sequence evolution and can be used there.
Baake, Baake, Baake, Barton, Boerlijst, Bonhoeffer, Bürger, Bürger, Bürger, Bürger, Charlesworth, Crow, Crow, Demetrius, Demetrius, Eigen, Eigen, Eigen, Ellen Baake, Ethier, Ewens, Franz, Gabriel, Gabriel, Gillespie, Haldane, Hermisson, Higgs, Hofbauer, Hofbauer, Holger Wagner, Huynen, Jagers, Joachim Hermisson, Karlin, Karlin, Kauffman, Kauffman, Kesten, Kimura, Kimura, Kondrashov, Kondrashov, Leuthäusser, Leuthäusser, Maynard Smith, Moran, Nowak, O'Brien, Ohta, Ohta, Oliver Redner, Otto, Phillips, Sniegowski, Swetina, Swofford, Tarazona, Taylor, Wagner, Wagner, Wagner, Waxman, Wiehe, Wilkinson   +64 more
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Combining experiments and simulations using the maximum entropy principle. [PDF]

PLoS Computational Biology, 2014
A key component of computational biology is to compare the results of computer modelling with experimental measurements. Despite substantial progress in the models and algorithms used in many areas of computational biology, such comparisons sometimes ...
Wouter Boomsma, Jesper Ferkinghoff-Borg, Kresten Lindorff-Larsen   +2 more
doaj   +1 more source

Principal eigenvalues for k-Hessian operators by maximum principle methods

Mathematics in Engineering, 2021
For fully nonlinear $k$-Hessian operators on bounded strictly $(k-1)$-convex domains $\Omega$ of $\R^N$, a characterization of the principal eigenvalue associated to a $k$-convex and negative principal eigenfunction will be given as the supremum over ...
Isabeau Birindelli, Kevin R. Payne
doaj   +1 more source

Maximum principle for stable operators

Mathematische Nachrichten, 2023
AbstractWe prove a weak maximum principle for nonlocal symmetric stable operators including the fractional Laplacian. The main focus of this work is on minimal regularity assumptions of the functions under consideration.
Grube, Florian, Hensiek, Thorben
openaire   +3 more sources