Results 61 to 70 of about 6,326,277 (372)
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Hopf maximum principle revisited
Electronic Journal of Differential Equations, 2015 A weak version of Hopf maximum principle for elliptic equations in divergence form $$ \sum_{i,j=1}^N\partial_i(a_{ij}(x)\partial_ju)=0 $$ with Holder continuous coefficients $a_{ij}$ was shown in [3], in the two-dimensional case.
Jose C. Sabina de Lis
doaj
Second-order maximum principle controlled weakly singular Volterra integral equations [PDF]
Archives of Control SciencesThis work studies a class of singular Volterra integral equations that are (controlled) and can be applied to memory-related problems. For optimum controls, we prove a second-order Pontryagin type maximal principle.
Jasarat J. Gasimov, Nazim I. Mahmudov
doaj +1 more source
On the maximum principle preserving schemes for the generalized Allen–Cahn equation
, 2016 This paper is concerned with the generalized Allen-Cahn equation with a nonlinear mobility that may be degenerate, which also includes an advection term appearing in many phase- field models for multi-component fluid flows.
Jie Shen, T. Tang, Jiang Yang
semanticscholar +1 more source
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
The Maximum Entropy Production Principle and Linear Irreversible Processes
Entropy, 2010 It is shown that Onsager’s principle of the least dissipation of energy is equivalent to the maximum entropy production principle. It is known that solutions of the linearized Boltzmann equation make extrema of entropy production.
Milan Brumen +5 more
doaj +1 more source
Maximum Entropy Production Principle for Stock Returns [PDF]
, 2014 In our previous studies we have investigated the structural complexity of time series describing stock returns on New York's and Warsaw's stock exchanges, by employing two estimators of Shannon's entropy rate based on Lempel-Ziv and Context Tree ...
Fiedor, Paweł
core
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Pontryagin Maximum Principle for Incommensurate Fractional-Orders Optimal Control Problems
Mathematics, 2023 We introduce a new optimal control problem where the controlled dynamical system depends on multi-order (incommensurate) fractional differential equations.
Faïçal Ndaïrou, Delfim F. M. Torres
doaj +1 more source
Molecular Oncology, EarlyView.Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova +26 more
wiley +1 more source