Results 61 to 70 of about 6,406,771 (368)

Maximum principle for stable operators

open access: yesMathematische Nachrichten, 2023
AbstractWe prove a weak maximum principle for nonlocal symmetric stable operators including the fractional Laplacian. The main focus of this work is on minimal regularity assumptions of the functions under consideration.
Grube, Florian, Hensiek, Thorben
openaire   +3 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Hopf maximum principle revisited

open access: yesElectronic Journal of Differential Equations, 2015
A weak version of Hopf maximum principle for elliptic equations in divergence form $$ \sum_{i,j=1}^N\partial_i(a_{ij}(x)\partial_ju)=0 $$ with Holder continuous coefficients $a_{ij}$ was shown in [3], in the two-dimensional case.
Jose C. Sabina de Lis
doaj  

Second-order maximum principle controlled weakly singular Volterra integral equations [PDF]

open access: yesArchives of Control Sciences
This work studies a class of singular Volterra integral equations that are (controlled) and can be applied to memory-related problems. For optimum controls, we prove a second-order Pontryagin type maximal principle.
Jasarat J. Gasimov, Nazim I. Mahmudov
doaj   +1 more source

Combining experiments and simulations using the maximum entropy principle. [PDF]

open access: yesPLoS Computational Biology, 2014
A key component of computational biology is to compare the results of computer modelling with experimental measurements. Despite substantial progress in the models and algorithms used in many areas of computational biology, such comparisons sometimes ...
Wouter Boomsma   +2 more
doaj   +1 more source

Principal eigenvalues for k-Hessian operators by maximum principle methods

open access: yesMathematics in Engineering, 2021
For fully nonlinear $k$-Hessian operators on bounded strictly $(k-1)$-convex domains $\Omega$ of $\R^N$, a characterization of the principal eigenvalue associated to a $k$-convex and negative principal eigenfunction will be given as the supremum over ...
Isabeau Birindelli, Kevin R. Payne
doaj   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Pontryagin Maximum Principle for Incommensurate Fractional-Orders Optimal Control Problems

open access: yesMathematics, 2023
We introduce a new optimal control problem where the controlled dynamical system depends on multi-order (incommensurate) fractional differential equations.
Faïçal Ndaïrou, Delfim F. M. Torres
doaj   +1 more source

Markov processes follow from the principle of Maximum Caliber

open access: yes, 2011
Markov models are widely used to describe processes of stochastic dynamics. Here, we show that Markov models are a natural consequence of the dynamical principle of Maximum Caliber.
Brockwell P. J.   +6 more
core   +1 more source

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