Results 71 to 80 of about 6,326,277 (372)

Stochastic global maximum principle for optimization with recursive utilities

open access: yes, 2017
In this paper, we study the recursive stochastic optimal control problems. The control domain does not need to be convex, and the generator of the backward stochastic differential equation can contain z.
Mingshang Hu
semanticscholar   +1 more source

Statistical equilibrium of tetrahedra from maximum entropy principle

open access: yes, 2019
Discrete formulations of (quantum) gravity in four spacetime dimensions build space out of tetrahedra. We investigate a statistical mechanical system of tetrahedra from a many-body point of view based on non-local, combinatorial gluing constraints that ...
Chirco, Goffredo   +2 more
core   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

Maximum Entropy Principle and the Higgs Boson Mass

open access: yes, 2014
A successful connection between Higgs boson decays and the Maximum Entropy Principle is presented. Based on the information theory inference approach we determine the Higgs boson mass as $M_H= 125.04\pm 0.25$ GeV, a value fully compatible to the LHC ...
Alves, Alexandre   +2 more
core   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

A new approach to the Pontryagin maximum principle for nonlinear fractional optimal control problems [PDF]

open access: yes, 2015
In this paper, we discuss a new general formulation of fractional optimal control problems whose performance index is in the fractional integral form and the dynamics are given by a set of fractional differential equations in the Caputo sense.
H. Ali, F. Pereira, S. Gama
semanticscholar   +1 more source

A stochastic maximum principle via Malliavin calculus [PDF]

open access: yes, 2008
This paper considers a controlled It\^o-L\'evy process where the information available to the controller is possibly less than the overall information.
Meyer-Brandis, Thilo   +2 more
core   +1 more source

On Hopf's Lemma and the Strong Maximum Principle

open access: yes, 2005
In this paper we consider Hopf's Lemma and the Strong Maximum Principle for supersolutions to a class of non elliptic equations. In particular we prove a sufficient condition for the validity of Hopf's Lemma and of the Strong Maximum Principle and we ...
Bertone, S.   +2 more
core   +2 more sources

Functional parameters of spermatozoa obtained by a new selection device

open access: yesFEBS Open Bio, EarlyView.
This study compares density gradient centrifugation and the LensHooke CA0™ device for sperm separation. DGC requires multiple steps, specialized equipment, and technical expertise. In contrast, the CA0 device offers key practical and methodological advantages, resulting in a faster, simpler, and more affordable sperm selection method.
Julio C. Chávez   +8 more
wiley   +1 more source

Maximum Configuration Principle for Driven Systems with Arbitrary Driving

open access: yesEntropy, 2018
Depending on context, the term entropy is used for a thermodynamic quantity, a measure of available choice, a quantity to measure information, or, in the context of statistical inference, a maximum configuration predictor.
Rudolf Hanel, Stefan Thurner
doaj   +1 more source

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