Results 141 to 150 of about 3,720,038 (289)
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Status of Pesticide Residue in Grapes of Bijapur (Karnataka) [PDF]
Grapes grown in Bijapur district (Karnataka) were analysed for pesticide residue content employing multiresidue analysis by gas liquid chromatography equipped with ECD and NPD detectors. All the fruit samples showed the presence of one or the other group
M.S. Yadawe, U.S. Pujeri, A.S. Pujar, S.C. Hiremath*,
core
Maximum residue levels:Fact or fiction?
Maximum residue levels (MRLs) are trading standards that represent the maximum residue that could be found if a crop protection product (CPP) is applied according to critical good agricultural practice (cGAP).
Travis, Kim Z. +3 more
core +1 more source
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Residue Number System Arithmetic Assisted M-ary Modulation
A residue number system based M-ary modem is proposed and its performance is evaluated over Gaussian channels. When one or two redundant moduli are employed, a signal-to-noise ratio gain of 1.2–2 dB was achieved for a 16-ary, 32-ary and 37-ary modem ...
Yang, L-L., Hanzo, L.
core +1 more source
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
The multifaceted roles of lysosomes in cancer
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Zeranol is one of the synthetic growth hormone produced from mycotoxin that could affect humanhealth. The objective of this study was to determine zeranol residue in beef meat imported from Australiaand New Zealand using Enzyme-Linked Immunosorbent Assay
Siti Khadijah +2 more
doaj

