Results 141 to 150 of about 3,720,038 (289)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Status of Pesticide Residue in Grapes of Bijapur (Karnataka) [PDF]

open access: yes, 2010
Grapes grown in Bijapur district (Karnataka) were analysed for pesticide residue content employing multiresidue analysis by gas liquid chromatography equipped with ECD and NPD detectors. All the fruit samples showed the presence of one or the other group
M.S. Yadawe, U.S. Pujeri, A.S. Pujar, S.C. Hiremath*,
core  

Maximum residue levels:Fact or fiction?

open access: yes, 2003
Maximum residue levels (MRLs) are trading standards that represent the maximum residue that could be found if a crop protection product (CPP) is applied according to critical good agricultural practice (cGAP).
Travis, Kim Z.   +3 more
core   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Residue Number System Arithmetic Assisted M-ary Modulation

open access: yes, 1999
A residue number system based M-ary modem is proposed and its performance is evaluated over Gaussian channels. When one or two redundant moduli are employed, a signal-to-noise ratio gain of 1.2–2 dB was achieved for a 16-ary, 32-ary and 37-ary modem ...
Yang, L-L., Hanzo, L.
core   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

The multifaceted roles of lysosomes in cancer

open access: yesMolecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Residu Zeranol dalam Daging Sapi yang Diimpor dari Australia dan Selandia Baru Melalui Pelabuhan Tanjung Priok (ZERANOL RESIDUE IN BEEF MEAT IMPORTED FROM AUSTRALIA AND NEW ZEALAND THROUGH THE PORT OF TANJUNG PRIOK)

open access: yesJurnal Veteriner, 2016
Zeranol is one of the synthetic growth hormone produced from mycotoxin that could affect humanhealth. The objective of this study was to determine zeranol residue in beef meat imported from Australiaand New Zealand using Enzyme-Linked Immunosorbent Assay
Siti Khadijah   +2 more
doaj  

Home - About - Disclaimer - Privacy