Results 81 to 90 of about 1,555,997 (313)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Variáveis ambientais na modelagem do grau de saturação do concreto

Revista IBRACON de Estruturas e Materiais
Com o objetivo de facilitar o cálculo do grau de saturação do concreto, visto que é um fator influente no coeficiente de difusão de íons cloreto no interior do concreto, foram elaborados modelos matemáticos que dispensam medições locais.
M. G. T. Peraça, A. T. C. Guimarães, H. C. Piccoli   +2 more
doaj   +1 more source

Statistical study of maximum temperature at Poona with special reference to forecasting of weekly maximum temperature

MAUSAM, 1956
 Seventy two years' maximum temperature data of Poona have been studied in this paper. The co-efficients of variability of mean monthly maximum temperatures have maxima in June and October, The frequency distribution of daily maximum temperature during April and May have been studied and found to be skew.
openaire   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

What was the surface temperature in central Antarctica during the last glacial maximum? [PDF]

, 2004
The temperature increase at Vostok (Antarctica) from the last glacial maximum to the present warm period is about 8°C based on the deuterium isotope profile.
Schwander, J., Schwander, Jakob, Barnola, J. M., Blunier, Thomas, Parrenin, Frédéric, Parrenin, F., Chappellaz, Jérôme, Barnola, Jean Marc, Blunier, T., Chappellaz, J.   +9 more
core   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

On estimation of the temperature maximum in intraluminal or intracavitary hyperthermia

International Journal of Hyperthermia, 2005
During intraluminal or intracavitary hyperthermia treatments, limited non-invasive temperature information is available, which may result in sub-optimal treatment control. This article describes a method for estimating temperature maximums and their corresponding locations in tissue heated by a cylindrical applicator with an incorporated cooling system,
Kok, H. P., van Haaren, P. M. A., van Dijk, J. D. P., Crezee, J.   +3 more
openaire   +3 more sources

Millennial temperature reconstruction intercomparison and evaluation [PDF]

, 2006
There has been considerable recent interest in paleoclimate reconstructions of the temperature history of the last millennium. A wide variety of techniques have been used.
J. Esper, Weber, SL, Juckes, MN, Allen, Myles, M. R. Allen, Juckes, M. N., M. N. Juckes, S. L. Weber, Briffa, KR, G. C. Hegerl, Esper, J., A. Moberg, Hegerl, GC, Weber, S. L., T. J. Osborn, Esper, J, Hegerl, G. C., Osborn, TJ, Allen, M. R., Moberg, A., Briffa, K. R., Osborn, T. J., Zorita, E., Moberg, A, K. R. Briffa, Allen, Myles R., Allen, MR   +26 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Anfis Based Reference Evapotranspiration (ET0) Estimation Using Limited and Different Climate Parameters

ISPEC Journal of Agricultural Sciences
This study aims to estimate the reference evapotranspiration (ET0) with adaptive neuro-fuzzy inference system (ANFIS). The calculation of ET0 requires climate data such as maximum and minimum temperature, wind speed, sunshine duration and humidity ...
Mualla KETEN GÖKKUŞ
doaj   +1 more source