Results 91 to 100 of about 5,237 (222)

Genomic and phenotypic characterization of the Oropouche virus strain implicated in the 2022–24 large‐scale outbreak in Brazil

open access: yesJournal of Medical Virology, Volume 96, Issue 10, October 2024.
Abstract The Orthobunyavirus oropoucheense species encompasses a group of arthropod‐borne zoonotic viruses transmitted by biting midges to animals including humans. Several large‐scale human outbreaks caused by the prototype member of this species, Oropouche virus (OROV) have been documented since the 1970s and were primarily confined to the Amazon ...
Elisa de A. N. Azevedo   +17 more
wiley   +1 more source

Frequency of resistance to methicillin and other antimicrobial agents among Staphylococcus aureus strains isolated from pigs and their human handlers in Trinidad [PDF]

open access: yes, 2014
Background: Methicillin-resistant Staphylococcus aureus (MRSA) has emerged recently worldwide in production animals, particularly pigs and veal calves, which act as reservoirs for MRSA strains for human infection.
Adesiyun AA   +52 more
core   +1 more source

Alpha‐mannosidase‐2 modulates arbovirus infection in a pathogen‐ and Wolbachia‐specific manner in Aedes aegypti mosquitoes

open access: yesInsect Molecular Biology, Volume 33, Issue 4, Page 362-371, August 2024.
Mosquito genetic background can modulate Wolbachia pathogen‐blocking phenotypes. The alpha‐mannosidase‐2 gene has previously been identified as a potential candidate. αMan2 CRISPR KO mutagenesis suppresses dengue virus titres but increases Mayaro virus titres, in Wolbachia‐uninfected mosquitoes.
Nadya Urakova   +12 more
wiley   +1 more source

GloPID-R report on chikungunya, o'nyong-nyong and Mayaro virus, part 3: Epidemiological distribution of Mayaro virus

open access: yesAntiviral Research, 2019
sponsorship: Global Research Collaboration for Infectious Disease ...
Pezzi, L.   +29 more
openaire   +3 more sources

Genome signatures, self-organizing maps and higher order phylogenies: a parametric analysis [PDF]

open access: yes, 2007
Genome signatures are data vectors derived from the compositional statistics of DNA. The self-organizing map (SOM) is a neural network method for the conceptualisation of relationships within complex data, such as genome signatures.
Gatherer, Derek
core   +4 more sources

Research progress toward the influence of mosquito salivary proteins on the transmission of mosquito‐borne viruses

open access: yesInsect Science, Volume 31, Issue 3, Page 663-673, June 2024.
Mosquito salivary proteins (MSPs) bear multitudinous functions, embracing facilitating blood feeding and affecting the infection of mosquito‐borne viruses (MBVs) via directly interplaying with MBVs or tuning the homeostasis of host cells. In vivo, MSPs can modulate host's innate and adaptive immunity, which in turn impacts the native infection at the ...
Zhao‐Yang Wang   +3 more
wiley   +1 more source

The interferon-stimulated gene IFITM3 restricts infection and pathogenesis of arthritogenic and encephalitic alphaviruses [PDF]

open access: yes, 2016
Host cells respond to viral infections by producing type I interferon (IFN), which induces the expression of hundreds of interferon-stimulated genes (ISGs).
Diamond, Michael S   +4 more
core   +2 more sources

Structural Relationships to Efficacy for Prazole‐Derived Antivirals

open access: yesAdvanced Science, Volume 11, Issue 18, May 15, 2024.
Characterization of a family of covalent prazole derivative adducts with the Tsg101 UEV domain finds roles for bulk and flexibility in antiviral efficacy and cytotoxicity, while opening avenues for further development of prazole‐based antiviral therapeutics that target Tsg101.
David A. Nyenhuis   +9 more
wiley   +1 more source

Performance assessment of a multi-epitope chimeric antigen for the serological diagnosis of acute Mayaro fever

open access: yesScientific Reports, 2021
Mayaro virus (MAYV), which causes mayaro fever, is endemic to limited regions of South America that may expand due to the possible involvement of Aedes spp. mosquitoes in its transmission. Its effective control will require the accurate identification of
Paloma Napoleão-Pêgo   +6 more
doaj   +1 more source

An unidentified cluster of infection in the Peruvian Amazon region [PDF]

open access: yes, 2015
Introduction: Bartonella bacilliformis is the etiological agent of Carrion’s disease, which is a neglected disease linked to people in low-socioeconomic populations in Andean valleys. An outbreak of B.
Bustamante, Pershing   +7 more
core   +3 more sources

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