Results 71 to 80 of about 3,543 (186)

Alphavirus nsP2: A Multifunctional Regulator of Viral Replication and Promising Target for Anti‐Alphavirus Therapies

open access: yesReviews in Medical Virology, Volume 35, Issue 2, March 2025.
ABSTRACT Alphaviruses are re‐emerging vector‐born pathogens that cause arthralgia or encephalitic diseases on a global scale. While a vaccine against chikungunya virus was recently approved, no vaccines currently exist for other alphaviruses, nor are there antiviral drugs for the treatment of alphavirus infections. Alphaviruses have positive‐strand RNA
Sainan Wang   +2 more
wiley   +1 more source

The NLRP3 inflammasome is involved with the pathogenesis of Mayaro virus

open access: yesPLOS Pathogens, 2019
Mayaro virus (MAYV) is an arbovirus that circulates in Latin America and is emerging as a potential threat to public health. Infected individuals develop Mayaro fever, a severe inflammatory disease characterized by high fever, rash, arthralgia, myalgia and headache.
Luiza A. de Castro-Jorge   +14 more
openaire   +4 more sources

Two Birds With One Stone: RNA Virus Strategies to Manipulate G3BP1 and Other Stress Granule Components

open access: yesWIREs RNA, Volume 16, Issue 2, March/April 2025.
Stress granules emerging during viral infection can play both pro‐ and antiviral roles. RNA viruses use various strategies to antagonize their formation, including the degradation, inhibition, or sequestration of G3BP1, a key stress granule protein. However, biochemical and structural insights into these mechanisms have been reported for only a handful
Moh Egy Rahman Firdaus   +3 more
wiley   +1 more source

Study on the infectivity of Chikungunya and Mayaro virus in blood components

open access: yes, 2021
Os arbovírus são responsáveis por doenças, esporádicas ou em epidemias, que podem ser graves ou debilitantes, com impacto significativo para a saúde humana no Brasil e no mundo, tornando importante o estudo de suas transmissibilidades por transfusão ...
Souza, Ana Beatriz dos Anjos
core   +1 more source

On Mayaro Beach, Trinidad

open access: yes, 2009
Colour: Black and white; Style: Landscape; Other: Unbordered, DividedA young man with his donkey on the Mayaro Beach. Printed on the back of the postcard: “The West Indian Picture Postcards 2G Series. Send for list. Algernon E.
Rust, R.
core   +1 more source

Chikungunya Virus: Unveiling Its Global Impact (2002–2024)

open access: yesInterdisciplinary Perspectives on Infectious Diseases, Volume 2025, Issue 1, 2025.
Chikungunya virus (CHIKV), an arbovirus transmitted by Aedes mosquitoes, has caused massive global epidemics, where it causes periodic outbreaks of febrile illness. In recent years, it has afflicted populations of Africa, South America, and Southeast Asia.
Rakhi Issrani   +8 more
wiley   +1 more source

A Novel Self‐Amplifying mRNA with Decreased Cytotoxicity and Enhanced Protein Expression by Macrodomain Mutations

open access: yesAdvanced Science, Volume 11, Issue 43, November 20, 2024.
This research shows an example that reducing innate immunogenicity to increase payload protein expression of self‐amplifying RNA via a single mutation in the macrodomain. The mutant saRNA attenuates the activation of the double‐stranded RNA sensor as well as the downstream interferon response.
Yue Gong   +5 more
wiley   +1 more source

Coconut Palms, Mayaro, Trinidad

open access: yes, 2009
Colour: Black and White; Style: Landscape; Other: Bordered, DividedAutomobiles park between the tall coconut trees along the shore as their occupants enjoy what is offered at Mayaro Beach, sun, sand and surf.Funding for this project has been provided by ...

core   +1 more source

Mayaro fever in an HIV-infected patient suspected of having Chikungunya fever

open access: yesRevista da Sociedade Brasileira de Medicina Tropical
Arboviruses impose a serious threat to public health services. We report a case of a patient returning from a work trip to the Amazon basin with myalgia, arthralgia, fever, and headache. During this travel, the patient visited riverside communities. Both
Cássia Fernanda Estofolete   +5 more
doaj   +1 more source

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