Results 61 to 70 of about 5,601 (244)

Arrival of Oropouche Virus in a Nonendemic Area in Northeastern Brazil, 2024

Journal of Medical Virology, Volume 98, Issue 1, January 2026.
ABSTRACT Orthobunyavirus oropoucheense (OROV) causes Oropouche fever, which exhibits symptoms similar to those of other arboviral diseases. Although it has historically been restricted to the Amazon region, the virus has recently spread to other areas of Brazil.
Jean P. M. Nascimento, Thiago P. G. Araújo, Mykaella A. Araújo, Mateus M. G. Arruda, Vitória P. Simplicio, Emelly B. Calheiros, Aline C. Pereira e Silva, Laura M. N. Silva, Marcus R. Santos, Magliones C. Lima, Hazerral O. Santos, Ênio J. Bassi, Alessandra A. Borges, Anderson B. Leite, Abelardo Silva‐Júnior   +14 more
wiley   +1 more source

Mayaro Virus Induction of Oxidative Stress is Associated With Liver Pathology in a Non-Lethal Mouse Model

Scientific Reports, 2019
Mayaro virus (MAYV) causes Mayaro fever in humans, a self-limiting acute disease, with persistent arthralgia and arthritis. Although MAYV has a remerging potential, its pathogenic mechanisms remain unclear.
Camila Carla da Silva Caetano, Fernanda Caetano Camini, Letícia Trindade Almeida, Ariane Coelho Ferraz, Tales Fernando da Silva, Rafaela Lameira Souza Lima, Mayara Medeiros de Freitas Carvalho, Thalles de Freitas Castro, Cláudia Martins Carneiro, Breno de Mello Silva, Silvana de Queiroz Silva, José Carlos de Magalhães, Cintia Lopes de Brito Magalhães   +12 more
doaj   +1 more source

Clinical, Serological, and Molecular Profile of Dengue Patients With Warning Signs During the 2024 Outbreak in Belo Horizonte, Brazil

Journal of Medical Virology, Volume 98, Issue 1, January 2026.
ABSTRACT Dengue poses a significant arboviral threat in Brazil, with 2024 recording the largest outbreak to date. This prospective observational study was conducted during the 2024 outbreak with unvaccinated patients at Eduardo de Menezes Hospital, Belo Horizonte.
Samille Henriques Pereira, Ana Paula Moreira Franco‐Luiz, Camila Tita Nogueira, Guilherme Otávio Varino Cornélio, Adelina Machado de Carvalho Nogueira, Vírginia Antunes de Andrade, Silvia Hees de Carvalho, Karen Cecília de Lima Torres, Vanessa Peruhype‐Magalhães, Olindo Assis Martins‐Filho, Jordana Grazziela Alves Coelho‐dos‐Reis, Andréa Teixeira‐Carvalho, Flávio Guimarães da Fonseca, Pedro Augusto Alves   +13 more
wiley   +1 more source

An update on the development of antiviral against Mayaro virus: from molecules to potential viral targets [PDF]

, 2023
Marina Paschoalino, Mikaela dos Santos Marinho, Igor Andrade Santos, Victória Riquena Grosche, Daniel Oliveira Silva Martins, Rafael Borges Rosa, Ana Carolina Gomes Jardim   +6 more
openalex   +1 more source

Exploring Bioactive Metabolites From Fusarium falciforme and Aspergillus terreus Isolated From Protease‐Rich Fruits: Antifungal, Antitrypanosomal, and Enzymatic Inhibitory Activities

Chemistry &Biodiversity, Volume 22, Issue 11, November 2025.
Metabolites from fungi isolated from protease rich‐fruits displayed antifungal, antitrypanosomal and enzymatic inhibitory activities. ABSTRACT Fungal secondary metabolites display remarkable chemical diversity and biological potential, with applications in agriculture and pharmaceuticals. This study isolated and characterized bioactive metabolites from
Gabriela de Oliveira Almeida, Vitor de Souza Mazucato, Ludmilla Tonani, Marcia Regina von Zeska Kress, Gisele Barbosa, Renata Krogh, Adriano Defini Andricopulo, Leonardo Luiz Gomes Ferreira, Paulo Cezar Vieira   +8 more
wiley   +1 more source

Cryo-EM structure of the mature and infective Mayaro virus at 4.4 Å resolution reveals features of arthritogenic alphaviruses

Nature Communications, 2021
Mayaro virus (MAYV) is an emerging arbovirus in Central and South America that is transmitted by mosquitoes and causes arthritogenic disease. Here, the authors present the 4.4 Å resolution cryo-EM structure of MAYV and describe specific features of the ...
Helder V. Ribeiro-Filho, Lais D. Coimbra, Alexandre Cassago, Rebeca P. F. Rocha, João Victor da Silva Guerra, Rafael de Felicio, Carolina Moretto Carnieli, Luiza Leme, Antonio Cláudio Padilha, Adriana F. Paes Leme, Daniela B. B. Trivella, Rodrigo Villares Portugal, Paulo Sérgio Lopes-de-Oliveira, Rafael Elias Marques   +13 more
doaj   +1 more source

The Halogen Effect in [Cu(NHC)X] Compounds: A Case Study on the Anti‐Leishmania and Antiviral Activity of [Cu(IPr)X]

ChemistrySelect, Volume 10, Issue 31, August 15, 2025.
This study explores how changing halidesfrom Cl to Iinfluences ionic radius, antioxidant activity, and lipophilicity. These shifts significantly impact the biological potency of [Cu(IPr)X] compounds against Leishmania parasites and arboviruses. A strategic tweak in halogen identity paves the way for enhanced therapeutic performance in metal‐based drug ...
J. V. Fontes, M. E. F. Agnoli, G. Clauss, M. S. A. Garcia, A. V. P. Ferreira, G. A. Antoniucci, A. L. Costa‐Oliveira, A.C.G. Jardim, D. C. Miguel, C. Abbehausen   +9 more
wiley   +1 more source

Virucidal activity of proanthocyanidin against Mayaro virus

Antiviral Research, 2019
Mayaro virus (MAYV) is a sublethal arbovirus transmitted by mosquitoes with possible installation of an urban cycle in the Americas. Its infection causes disabling arthralgia, and still, there is no vaccine or treatment to it. We recently investigated nearly 600 compounds by molecular docking and identified epicatechin as a potent antiviral against ...
Ariane Coelho, Ferraz, Thaís de Fátima Silva, Moraes, Waleska Stephanie da Cruz, Nizer, Michelli Dos, Santos, Antônio Helvécio, Tótola, Jaqueline Maria Siqueira, Ferreira, Sidney Augusto, Vieira-Filho, Vanessa Gonçalves, Rodrigues, Lucienir Pains, Duarte, Cintia Lopes, de Brito Magalhães, José Carlos, de Magalhães   +10 more
openaire   +2 more sources

GloPID-R report on chikungunya, o'nyong-nyong and Mayaro virus, part 3: Epidemiological distribution of Mayaro virus

Antiviral Research, 2019
sponsorship: Global Research Collaboration for Infectious Disease ...
Pezzi, L., Rodriguez-Morales, A.J., Reusken, C.B., Ribeiro, G.S., LaBeaud, A.D., Lourenco-de-Oliveira, R., Brasil, P., Lecuit, M., Failloux, A.B., Gallian, P., Jaenisch, T., Simon, F., Siqueira, A.M., Rosa-Freitas, M.G., Rua, A. Vega, Weaver, S.C., Drexler, J.F., Vasilakis, N., de Lamballerie, X., Boyer, S., Busch, M., Diallo, M., Diamond, M.S., Drebot, M.A., Kohl, A., Neyts, J., Ng, L.FP., Rios, M., Sall, A., Simmons, G.   +29 more
openaire   +5 more sources

Genetic analysis of members of the species Oropouche virus and identification of a novel M segment sequence [PDF]

, 2015
Oropouche virus (OROV) is a public health threat in South America, and in particular Northern Brazil, causing frequent outbreaks of febrile illness.
Azevedo, Raimunda S.S., da Silva, Daisy E.A., Elliott, Richard M., Hughes, Joseph, Nunes, Marcio R.T., Olszanski Acrani, Gustavo, Rodrigues, Sueli G., Tilston-Lunel, Natasha L., Vasconcelos, Pedro F.C.   +8 more
core   +1 more source