Results 61 to 70 of about 3,543 (186)

Arrival of Oropouche Virus in a Nonendemic Area in Northeastern Brazil, 2024

Journal of Medical Virology, Volume 98, Issue 1, January 2026.
ABSTRACT Orthobunyavirus oropoucheense (OROV) causes Oropouche fever, which exhibits symptoms similar to those of other arboviral diseases. Although it has historically been restricted to the Amazon region, the virus has recently spread to other areas of Brazil.
Jean P. M. Nascimento, Thiago P. G. Araújo, Mykaella A. Araújo, Mateus M. G. Arruda, Vitória P. Simplicio, Emelly B. Calheiros, Aline C. Pereira e Silva, Laura M. N. Silva, Marcus R. Santos, Magliones C. Lima, Hazerral O. Santos, Ênio J. Bassi, Alessandra A. Borges, Anderson B. Leite, Abelardo Silva‐Júnior   +14 more
wiley   +1 more source

Cryo-EM structure of the mature and infective Mayaro virus at 4.4 Å resolution reveals features of arthritogenic alphaviruses

Nature Communications, 2021
Mayaro virus (MAYV) is an emerging arbovirus in Central and South America that is transmitted by mosquitoes and causes arthritogenic disease. Here, the authors present the 4.4 Å resolution cryo-EM structure of MAYV and describe specific features of the ...
Helder V. Ribeiro-Filho, Lais D. Coimbra, Alexandre Cassago, Rebeca P. F. Rocha, João Victor da Silva Guerra, Rafael de Felicio, Carolina Moretto Carnieli, Luiza Leme, Antonio Cláudio Padilha, Adriana F. Paes Leme, Daniela B. B. Trivella, Rodrigo Villares Portugal, Paulo Sérgio Lopes-de-Oliveira, Rafael Elias Marques   +13 more
doaj   +1 more source

Clinical, Serological, and Molecular Profile of Dengue Patients With Warning Signs During the 2024 Outbreak in Belo Horizonte, Brazil

Journal of Medical Virology, Volume 98, Issue 1, January 2026.
ABSTRACT Dengue poses a significant arboviral threat in Brazil, with 2024 recording the largest outbreak to date. This prospective observational study was conducted during the 2024 outbreak with unvaccinated patients at Eduardo de Menezes Hospital, Belo Horizonte.
Samille Henriques Pereira, Ana Paula Moreira Franco‐Luiz, Camila Tita Nogueira, Guilherme Otávio Varino Cornélio, Adelina Machado de Carvalho Nogueira, Vírginia Antunes de Andrade, Silvia Hees de Carvalho, Karen Cecília de Lima Torres, Vanessa Peruhype‐Magalhães, Olindo Assis Martins‐Filho, Jordana Grazziela Alves Coelho‐dos‐Reis, Andréa Teixeira‐Carvalho, Flávio Guimarães da Fonseca, Pedro Augusto Alves   +13 more
wiley   +1 more source

Exploring Bioactive Metabolites From Fusarium falciforme and Aspergillus terreus Isolated From Protease‐Rich Fruits: Antifungal, Antitrypanosomal, and Enzymatic Inhibitory Activities

Chemistry &Biodiversity, Volume 22, Issue 11, November 2025.
Metabolites from fungi isolated from protease rich‐fruits displayed antifungal, antitrypanosomal and enzymatic inhibitory activities. ABSTRACT Fungal secondary metabolites display remarkable chemical diversity and biological potential, with applications in agriculture and pharmaceuticals. This study isolated and characterized bioactive metabolites from
Gabriela de Oliveira Almeida, Vitor de Souza Mazucato, Ludmilla Tonani, Marcia Regina von Zeska Kress, Gisele Barbosa, Renata Krogh, Adriano Defini Andricopulo, Leonardo Luiz Gomes Ferreira, Paulo Cezar Vieira   +8 more
wiley   +1 more source

Virucidal activity of proanthocyanidin against Mayaro virus

Antiviral Research, 2019
Mayaro virus (MAYV) is a sublethal arbovirus transmitted by mosquitoes with possible installation of an urban cycle in the Americas. Its infection causes disabling arthralgia, and still, there is no vaccine or treatment to it. We recently investigated nearly 600 compounds by molecular docking and identified epicatechin as a potent antiviral against ...
Ariane Coelho, Ferraz, Thaís de Fátima Silva, Moraes, Waleska Stephanie da Cruz, Nizer, Michelli Dos, Santos, Antônio Helvécio, Tótola, Jaqueline Maria Siqueira, Ferreira, Sidney Augusto, Vieira-Filho, Vanessa Gonçalves, Rodrigues, Lucienir Pains, Duarte, Cintia Lopes, de Brito Magalhães, José Carlos, de Magalhães   +10 more
openaire   +2 more sources

The Halogen Effect in [Cu(NHC)X] Compounds: A Case Study on the Anti‐Leishmania and Antiviral Activity of [Cu(IPr)X]

ChemistrySelect, Volume 10, Issue 31, August 15, 2025.
This study explores how changing halidesfrom Cl to Iinfluences ionic radius, antioxidant activity, and lipophilicity. These shifts significantly impact the biological potency of [Cu(IPr)X] compounds against Leishmania parasites and arboviruses. A strategic tweak in halogen identity paves the way for enhanced therapeutic performance in metal‐based drug ...
J. V. Fontes, M. E. F. Agnoli, G. Clauss, M. S. A. Garcia, A. V. P. Ferreira, G. A. Antoniucci, A. L. Costa‐Oliveira, A.C.G. Jardim, D. C. Miguel, C. Abbehausen   +9 more
wiley   +1 more source

Inhibition of Mayaro virus infection by bovine lactoferrin

Virology, 2014
Mayaro virus (MAYV) is an arbovirus linked to several sporadic outbreaks of a highly debilitating febrile illness in many regions of South America. MAYV is on the verge of urbanization from the Amazon region and no effective antiviral intervention is available against human infections.
Carvalho, Carlos A.M., Sousa, Ivanildo P., Silva, Jerson L., Oliveira, Andréa C., Gonçalves, Rafael B., Gomes, Andre M.O.   +5 more
openaire   +2 more sources

Integrating Citizen Science and Remote Sensing Data to Identify Key Environmental Factors Influencing H5N1 Avian Influenza Virus Potential Spillover Risk in the Philippines

GeoHealth, Volume 9, Issue 8, August 2025.
Abstract Highly pathogenic avian influenza (HPAI) virus presents a serious threat to poultry and public health worldwide, with transmission dynamics shaped by avian migration patterns and environmental conditions. Recent outbreaks in the Philippines highlight the urgent need for effective control measures.
John Oliver Sayseng, Ting‐Wu Chuang
wiley   +1 more source

Clinical, Epidemiological, and Laboratory Features of Mayaro Virus Infection: a Systematic Review

, 2023
Purpose of Review: Mayaro virus is an arbovirus that circulates in a wild cycle transmitted by Haemagogus janthinomys; however, case reports in urban areas suggest that other arthropods could be acting as vectors.
Silva-Ramos, C.R., Mejorano-Fonseca, J.A., Hidalgo, M., Rodríguez-Morales, A.J., Faccini-Martínez, Á.A.   +4 more
core   +1 more source

Seroprevalence of Chikungunya and O'nyong‐nyong Viruses in Senegal, West Africa

Journal of Medical Virology, Volume 97, Issue 3, March 2025.
ABSTRACT Arthritogenic alphaviruses such as chikungunya (CHIKV) and o'nyong‐nyong (ONNV) viruses have shown capacity to cause widespread epidemics, with recurrent and sporadic outbreaks occurring throughout sub‐Saharan Africa. We analyzed the seroprevalence for CHIKV and ONNV in 470 non‐febrile subjects from three regions in Senegal (Sindia, 2018 ...
Prince Baffour Tonto, Mouhamad Sy, Ibrahima Mbaye Ndiaye, Mariama Toure, Amy Gaye, Mariama Aidara, Amadou Moctar Mbaye, Abdoulaye Kane Dia, Mamadou Alpha Diallo, Jules Francois Gomis, Mamadou Samb Yade, Younous Diedhiou, Baba Dieye, Khadim Diongue, Mame Cheikh Seck, Aida S. Badiane, Bobby Brooke Herrera, Daouda Ndiaye   +17 more
wiley   +1 more source