Results 81 to 90 of about 5,601 (244)

Experimental Transmission of Mayaro Virus by Aedes aegypti [PDF]

The American Society of Tropical Medicine and Hygiene, 2011
Outbreaks of Mayaro fever have been associated with a sylvatic cycle of Mayaro virus (MAYV) transmission in South America. To evaluate the potential for a common urban mosquito to transmit MAYV, laboratory vector competence studies were performed with Aedes aegypti from Iquitos, Peru. Oral infection in Ae.
Kanya C, Long, Sarah A, Ziegler, Saravanan, Thangamani, Nicole L, Hausser, Tadeusz J, Kochel, Stephen, Higgs, Robert B, Tesh   +6 more
openaire   +2 more sources

A Novel Self‐Amplifying mRNA with Decreased Cytotoxicity and Enhanced Protein Expression by Macrodomain Mutations

Advanced Science, Volume 11, Issue 43, November 20, 2024.
This research shows an example that reducing innate immunogenicity to increase payload protein expression of self‐amplifying RNA via a single mutation in the macrodomain. The mutant saRNA attenuates the activation of the double‐stranded RNA sensor as well as the downstream interferon response.
Yue Gong, Danni Yong, Gensheng Liu, Jiang Xu, Jun Ding, William Jia   +5 more
wiley   +1 more source

Emerging alphaviruses in the Americas: Chikungunya and Mayaro [PDF]

Revista da Sociedade Brasileira de Medicina Tropical, 2014
Chikungunya virus (CHIKV) and Mayaro virus (MAYV) are emergent arthropod-borne viruses that produce outbreaks of acute febrile illness with arthropathy. Despite their different continental origins, CHIKV and MAYV are closely related and are components of the Semliki Forest Complex of the Alphavirus (Togaviridae).
Figueiredo, Mario Luis Garcia de, Figueiredo, Luiz Tadeu Moraes   +1 more
openaire   +5 more sources

Deltas: New paradigms

The Depositional Record, Volume 10, Issue 5, Page 600-636, November 2024.
This paper discusses some new paradigms concerning the origin and significance of deltas and their deposits. It proposes a broader definition of deltas that takes into account the importance of sediment‐laden fluvial discharges in controlling deltaic sedimentation.
Carlos Zavala, Mariano Arcuri, Agustin Zorzano, Valentín Trobbiani, Antonela Torresi, Ainara Irastorza   +5 more
wiley   +1 more source

Obesity's Unexpected Influence: Reduced Alphavirus Transmission and Altered Immune Activation in the Vector

Journal of Medical Virology, Volume 96, Issue 11, November 2024.
ABSTRACT Chikungunya virus (CHIKV) and Mayaro virus (MAYV) are emerging/re‐emerging alphaviruses transmitted by Aedes spp. mosquitoes and responsible for recent disease outbreaks in the Americas. The capacity of these viruses to cause epidemics is frequently associated with increased mosquito transmission, which in turn is governed by virus−host−vector
Pallavi Rai, Emily M. Webb, Sally L. Paulson, Lin Kang, James Weger‐Lucarelli   +4 more
wiley   +1 more source

Frequency of resistance to methicillin and other antimicrobial agents among Staphylococcus aureus strains isolated from pigs and their human handlers in Trinidad [PDF]

, 2014
Background: Methicillin-resistant Staphylococcus aureus (MRSA) has emerged recently worldwide in production animals, particularly pigs and veal calves, which act as reservoirs for MRSA strains for human infection.
Adesiyun AA, Adesiyun AA, Akpaka PE, Ben Slama K, Boucher H, Chen R, Choi CS, Data P, De Neeling AJ, Del Giudice P, Dorobãt OM, Dressler AE, Faires MC, Felten A, Flayhart D, French GL, Fwity B, Garcia-Graells C, Glenn D, Gootz TD, Graveland H, Haenni M, Haque N, Hartmann FA, Holmes MA, Jarvis WR, Jensen SO, Kerwat K, Lewis HC, Magiorakos AP, Malhotra-Kumar S, Maree CL, Meemken D, Mine Y, Moodley A, Morris DO, Munckhof WJ, Nonhoff C, Perry JD, Piskin N, Pletinckx LJ, Porrero MC, Riesen A, Rijnders MIa, Rubin JL, Saxema S, Shrestha B, Smith TC, Tenhagen BA, Tiwari HK, Van Cleef BA, Weese JS, Wulf MW   +52 more
core   +1 more source

Inhibition of Mayaro virus infection by bovine lactoferrin

Virology, 2014
Mayaro virus (MAYV) is an arbovirus linked to several sporadic outbreaks of a highly debilitating febrile illness in many regions of South America. MAYV is on the verge of urbanization from the Amazon region and no effective antiviral intervention is available against human infections.
Carvalho, Carlos A.M., Sousa, Ivanildo P., Silva, Jerson L., Oliveira, Andréa C., Gonçalves, Rafael B., Gomes, Andre M.O.   +5 more
openaire   +2 more sources

Applications and advancements in animal models for antiviral research on mosquito‐borne arboviruses

Animal Models and Experimental Medicine, Volume 7, Issue 5, Page 673-684, October 2024.
Animal models are crucial in antiviral research on mosquito‐borne arboviruses, playing a role in understanding disease mechanisms, vaccine development, and toxicity testing. The use of animal models confronts hurdles related to ethical considerations and the successful translation of findings from animals to humans.
Megan Caifeng Tang, Ka Heng Wong, Adzzie Shazleen Azman, Rafidah Lani   +3 more
wiley   +1 more source

Mayaro fever in an HIV-infected patient suspected of having Chikungunya fever

Revista da Sociedade Brasileira de Medicina Tropical
Arboviruses impose a serious threat to public health services. We report a case of a patient returning from a work trip to the Amazon basin with myalgia, arthralgia, fever, and headache. During this travel, the patient visited riverside communities. Both
Cássia Fernanda Estofolete, Mânlio Tasso Oliveira Mota, Danila Vedovello, Delzi Vinha Nunes de Góngora, Irineu Luiz Maia, Maurício Lacerda Nogueira   +5 more
doaj   +1 more source

Characterization of Systemic Disease Development and Paw Inflammation in a Susceptible Mouse Model of Mayaro Virus Infection and Validation Using X-ray Synchrotron Microtomography [PDF]

, 2023
Ana Carolina de Carvalho, Carlos Sato Baraldi Dias, Laís D. Coimbra, Rebeca de Paiva Fróes Rocha, Alexandre Borin, Marina Alves Fontoura, Murilo de Carvalho, Paul Proost, Maurício Lacerda Nogueira, Sílvio Roberto Consonni, Renata Sesti‐Costa, Rafael Elias Marques   +11 more
openalex   +1 more source