Results 111 to 120 of about 16,448 (221)

Genetics of skin color variation in Europeans: genome-wide association studies with functional follow-up [PDF]

, 2015
In the International Visible Trait Genetics (VisiGen) Consortium, we investigated the genetics of human skin color by combining a series of genome-wide association studies (GWAS) in a total of 17,262 Europeans with functional follow-up of discovered loci.
Bataille, V. (Veronique), Chaitanya, L.C. (Lakshmi), Duffy, D.L. (David), Glass, D. (Daniel), Henders, A.K. (Anjali), Hofman, A. (Albert), Hysi, P.G. (Pirro), IJcken, W.F.J. (Wilfred) van, Jacobs, L.C. (Leonie), Kayser, M.H. (Manfred), Lao Grueso, O. (Oscar), Liu, F. (Fan), Mangino, M. (Massimo), Martin, N.G. (Nicholas), Montgomery, G.W. (Grant), Nijsten, T.E.C. (Tamar), Palstra, R.-J.T.S. (Robert-Jan), Rivadeneira Ramirez, F. (Fernando), Spector, T.D. (Timothy), Sturm, R.A. (Richard A.), Uitterlinden, A.G. (André), Visser, M. (Mijke), Walsh, S. (Susan), Wollstein, A. (Andreas), Zhong, K. (Kaiyin), Zhu, G. (Gu)   +25 more
core   +1 more source

Quercetin and Its Nano‐Based Formulations Against Skin Cancer: A Narrative Review

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Skin cancer is one of the most prevalent malignancies worldwide, characterized by the abnormal growth of skin cells and significant clinical challenges. Conventional treatments—including surgery, chemotherapy, and radiotherapy—often suffer from limitations such as adverse side effects, tumor resistance, and inadequate efficacy.
Mahtab Khanyabzadeh, Alireza Emamifar, Nikoo Emtiazi, Amir Nazari, Masoumeh Shekarriz, Amin Karami, Fateme Hashem Beik Mahallati, Rahineh Nomani Lafmejani, Atieh Dariush, Seyed Mohammad Mahdi Rohani, Elaheh Mohseni Vadeghani, Negin Khoshnood, Hamid Reza Ojaghi, Fatemeh Rezaei‐Tazangi, Reza Arefnezhad   +14 more
wiley   +1 more source

Pigmentary Markers in Danes--Associations with Quantitative Skin Colour, Nevi Count, Familial Atypical Multiple-Mole, and Melanoma Syndrome.

PLoS ONE, 2016
To investigate whether pigmentation genes involved in the melanogenic pathway (melanogenesis) contributed to melanoma predisposition, we compared pigmentary genetics with quantitative skin pigmentation measurements, the number of atypical nevi, the total
Peter Johansen, Jeppe Dyrberg Andersen, Linnea Nørgård Madsen, Henrik Ullum, Martin Glud, Claus Børsting, Robert Gniadecki, Niels Morling   +7 more
doaj   +1 more source

Histologic and phenotypic factors and MC1R status associated with BRAF(V600E), BRAF(V600K), and NRAS mutations in a community-based sample of 414 cutaneous melanomas [PDF]

, 2016
Cutaneous melanomas arise through causal pathways involving interplay between exposure to UV radiation and host factors, resulting in characteristic patterns of driver mutations in BRAF, NRAS, and other genes.
Green, Adele C., Hacker, Elke, Hayward, Nicholas K., Kvaskoff, Marina, Mortimore, Rohan, Olsen, Catherine M., Pandeya, Nirmala, Triscott, Joe, Whiteman, David C., Williamson, Richard M., Wood, Dominic, Yeo, Abrey   +11 more
core   +2 more sources

La genètica de la pigmentació humana i de la predisposició al càncer de pell [PDF]

, 2016
Els trets de pigmentació humana, incloent-hi el color dels ulls, de la pell i del cabell, són els trets físics més visibles i diferenciables entre individus.
Hernando, Barbara, Martinez-Cadenas, Conrado   +1 more
core   +1 more source

The Effect Estrogen and Testosterone on the Expression of Melanogenesis-related Genes in Korean Brindle Cattle

Journal of Animal Reproduction and Biotechnology, 2018
The purpose of this study is to expression pattern of melanogenesis associate genes on cultured melanocyte layer cells in Korean Brindle Cattle(Dark, Brindle and Yellow) were analyzed to evaluate the effects of sex hormones on the control of ...
Hui-Gyeong Seo, Ji-Hye Lee, Sang-Hwan Kim, Ho-Jun Lee, Jong-Taek Yoon   +4 more
doaj   +1 more source

Interaction between the melanocortin 1 receptor (MC1R) and agouti signalling protein genes (ASIP), and their association with black and brown coat colour phenotypes in peruvian alpaca

Italian Journal of Animal Science, 2020
The aim of this work was to assess the interaction between MC1R and ASIP genes in determining coat colour variation in black and brown Peruvian alpacas. Skin biopsies were collected from 25 black alpacas and 15 brown alpacas.
Stefano Pallotti, Bathrachalam Chandramohan, Dario Pediconi, Cristina Nocelli, Antonietta La Terza, Carlo Renieri   +5 more
doaj   +1 more source

A Common Variant in the MC1R Gene (p.V92M) is associated with Alzheimer's Disease Risk. [PDF]

, 2017
Despite the recent identification of some novel risk genes for Alzheimer's disease (AD), the genetic etiology of late-onset Alzheimer's disease (LOAD) remains largely unknown.
Alcolea, Daniel, Antonell, Anna, Badenas Orquin, Celia, Clarimón, Jordi, Fernandez-Santiago, Rubén, Fortea Ormaechea, Juan, Lladó Plarrumaní, Albert, Lleó Bisa, Alberto, Molinuevo, José Luis, Plana, Estel, Potrony Mateu, Míriam, Puig Butillé, Joan Anton, Puig i Sardà, Susana, Sánchez del Valle Díaz, Raquel, Tell Martí, Gemma   +14 more
core   +1 more source

Sequence Variation of Melanocortin 1 Receptor (MC1R) Gene and Association with Plumage Color in Domestic Geese

The Journal of Poultry Science, 2014
In contrast to other domestic and wild animals, the genetic variation of MC1R gene and association with plumage color has not been investigated in domestic goose.
Jing Huang, Bing Zhou, Da-Qian He, Shi-Yi Chen, Qing Zhu, Yong-Gang Yao, Yi-Ping Liu   +6 more
doaj   +1 more source

Identification of MC1R SNPs and their Association with Plumage Colors in Asian Duck

The Journal of Poultry Science, 2017
The melanocortin 1 receptor (MC1R) gene is a candidate functional gene that controls the pigment production in melanocytes. The aim of this study was to identify polymorphisms and investigate the effect of the MC1R gene on plumage coloration in duck ...
Hasina Sultana, Dong-Won Seo, Hee-Bok Park, Nu-Ri Choi, Md. Rashedul Hoque, Md. Shamsul Alam Bhuiyan, Kang-Nyeong Heo, Seung-Hwan Lee, Jun-Heon Lee   +8 more
doaj   +1 more source