Results 181 to 190 of about 12,611 (227)

The role of MC1R gene in buffalo coat color

Science China Life Sciences, 2010
Melanocortin-1 receptor (MC1R) plays a major role in pigmentation in many species. To investigate if the MC1R gene is associated with coat color in water buffalo, the coding region of MC1R gene of 216 buffalo samples was sequenced, which included 49 black river buffalo (Murrah and Nili-Ravi), 136 swamp buffalo (Dehong, Diandongnan, Dechang, Guizhou ...
YongWang, Miao, GuiSheng, Wu, Lei, Wang, DaLin, Li, ShouKun, Tang, JianPing, Liang, HuaMing, Mao, HuaiRong, Luo, YaPing, Zhang   +8 more
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Determination of Phenotype Associated SNPs in the MC1R Gene^*

Journal of Forensic Sciences, 2007
ABSTRACT: Prediction of physical appearance based on genetic analysis is a very attractive prospect for forensic investigations. Recent studies have proved that there is a significant association between some genetic variants of the melanocortin 1 receptor (MC1R) gene and red hair color.
Wojciech, Branicki, Urszula, Brudnik, Tomasz, Kupiec, Paulina, Wolañska-Nowak, Anna, Wojas-Pelc   +4 more
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O gene MC1R e a pigmentação dos animais

Genética na Escola, 2013
As cores observadas nos animais são resultantes da presença de pigmentos nos tecidos biológicos. Por ser uma característica de grande variabilidade, a coloração dos animais é alvo de estudos que buscam a compreensão a respeito dos mecanismos responsáveis por seu controle e diversidade.
Josmael Corso, Diego Hepp
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Determination of forensically relevant SNPs in the MC1R gene

International Congress Series, 2006
Abstract Genetic prediction of physical appearance is a very attractive prospect for forensic investigations. The association between some genetic variants of the MC1R gene and red hair colour has been already proved. Our study focuses on the potential forensic applicability of variation within this pigmentary gene. The obtained results indicate that
W. Branicki, T. Kupiec, P. Wolańska-Nowak, U. Brudnik   +3 more
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Variations of Melanocortin Receptor 1 (MC1R) Gene in Three Pig Breeds

Journal of Genetics and Genomics, 2007
Variations of Melanocortin Receptor 1 (MC1R) were investigated using sequencing, PCR-RFLP and PCR-SSCP, in three pig breeds, Landrace, Yorkshire, and Duroc. Five polymorphic sites were found, in which 668G-->C occurred within 5' UTR, nt894insCC in coding region resulting in a premature stop at codon 56, and 1318C-->T, 1554G-->A, 1197G-->A in coding ...
Guiling, Dun, Xianglong, Li, Hongzhan, Cao, Rongyan, Zhou, Lanhui, Li   +4 more
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Quantitative analysis of MC1R gene expression in human skin cell cultures

Pigment Cell Research, 2005
SummaryTo address the issue of melanocortin‐1 receptor (MC1R) expression in non‐melanocytic cells, we have quantitatively evaluated the relative expression levels of both MC1R mRNA and protein in a subset of different cell types. Using semi‐quantitative reverse transcriptase‐polymerase chain reaction (RT‐PCR) at high cycle numbers, we detected MC1R ...
Roberts, D. W., Newton, R. A., Beaumont, K. A., Leonard, J. H., Sturm, R. A.   +4 more
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ADAPTIVE REPTILE COLOR VARIATION AND THE EVOLUTION OF THE MC1R GENE

Evolution, 2004
The wealth of information on the genetics of pigmentation and the clear fitness consequences of many pigmentation phenotypes provide an opportunity to study the molecular basis of an ecologically important trait. The melanocortin-1 receptor (Mc1r) is responsible for intraspecific color variation in mammals and birds.
Rosenblum, Erica Bree, Hoekstra, Hopi, Nachman, Michael W.   +2 more
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[MC1R--the key gene in mammalian melanin synthesis].

Yi chuan = Hereditas, 2006
The study of the molecular regulation mechanism of melanin synthesis during animal development has become a new focus recently . The synthesis and production of melanin during animal development are regulated by many genes. This paper summarized the molecular function mechanism of melanocortin-1-receptor (MC1R) gene and the relationship between the ...
Yong-Sheng, Yang, Ning, Li, Xue-Mei, Deng, Chang-Xin, Wu   +3 more
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Sequence variation in the Mc1r gene for a group of polymorphic snakes

Gene, 2013
Studying the genetic factors underlying phenotypic traits can provide insight into dynamics of selection and molecular basis of adaptation, but this goal can be difficult for non-model organisms without extensive genomic resources. However, sequencing candidate genes for the trait of interest can facilitate the study of evolutionary genetics in natural
Christian L, Cox, Alison R Davis, Rabosky, Paul T, Chippindale   +2 more
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MC1R gene variants and sporadic malignant melanoma susceptibility in the Canary Islands population

Archives of Dermatological Research, 2013
Several MC1R variants are associated with increased risk of malignant melanoma (MM) in a variety of populations. We aim to examine the influence of the MC1R variants (RHC: D84E, R151C, R160W; NRHC: V60L, R163Q and the synonymous polymorphism T314T) on the MM risk in a population from the Canary Islands.
Córdoba Lanús, Aída Elizabeth, Hernández Jiménez, José G., Medina Coello, Chaxiraxi, Espinoza Jiménez, Adriana, González, Ana, Rodríguez Pérez, María del Cristo, Carretero Hernández, Gregorio, Almeida, Pablo, Suárez Hernández, José, Perera Molinero, Antonio, Fernández de Misa, Ricardo   +10 more
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