The melanocortin receptors and their accessory proteins. [PDF]
, 2013 The five melanocortin receptors (MCRs) named MC1R-MC5R have diverse physiological roles encompassing pigmentation, steroidogenesis, energy homeostasis and feeding behavior as well as exocrine function.
Chan, LF +3 more
core +2 more sources
PLoS ONE, 2013 The association between polymorphism at the mc1r locus and colour variation was studied in two wall lizard species (Podarcis lilfordi and P. pityusensis) from the Balearic archipelago.
Joana M Buades +7 more
doaj +1 more source
Antimicrobial peptides: agents of border protection for companion animals. [PDF]
, 2012 Over the past 20 years, there have been significant inroads into understanding the roles of antimicrobial peptides in homeostatic functions and their involvement in disease pathogenesis.
Affolter, Verena K +2 more
core +1 more source
Pigment Intensity in Dogs is Associated with a Copy Number Variant Upstream of KITLG. [PDF]
, 2020 Dogs exhibit a wide variety of coat color types, and many genes have been identified that control pigment production, appearance, and distribution. Some breeds, such as the Nova Scotia Duck Tolling Retriever (NSDTR), exhibit variation in pheomelanin ...
Affolter, Verena +6 more
core +2 more sources
MC1R gene analysis applied to breed traceability of beef [PDF]
Italian Journal of Animal Science, 2006 Since the breed of origin highly affects the beef price, reliable methods are needed to detect incorrect declarations. As most breeds are standardised for coat colour, the Melanocortin 1 Receptor gene (MC1R), involved in the regulation of eu/pheomelanins synthesis, has been suggested as marker for breed traceability of products of animal origin.
A. Rolando, DI STASIO, Liliana
openaire +4 more sources
An heuristic filtering tool to identify phenotype-associated genetic variants applied to human intellectual disability and canine coat colors [PDF]
, 2015 Background: Identification of one or several disease causing variant(s) from the large collection of variants present in an individual is often achieved by the sequential use of heuristic filters.
Bosmans, Tim +8 more
core +5 more sources
Coat colour phenotype of Qingyu pig is associated with polymorphisms of melanocortin receptor 1 gene [PDF]
Asian-Australasian Journal of Animal Sciences, 2017 Objective Qingyu pig, a Chinese indigenous pig breed, exhibits two types of coat colour phenotypes, including pure black and white with black spotting respectively.
Xiaoqian Wu +11 more
doaj +1 more source
Identification of the minimal melanocyte-specific promoter in the melanocortin receptor 1 gene
Journal of Experimental & Clinical Cancer Research, 2008 Background The understanding of cutaneous pigmentation biology is relevant from the biologic and clinical point of view. The binding of α-melanocortin and its specific receptor, on the plasma membrane of melanin synthesising cells, plays a crucial role ...
Natali Pier +4 more
doaj +1 more source
Inherited variation at MC1R and histological characteristics of primary melanoma. [PDF]
PLoS ONE, 2015 Variation in the melanocortin-1receptor (MC1R) gene is associated with pigmentary phenotypes and risk of malignant melanoma. Few studies have reported on MC1R variation with respect to tumor characteristics, especially clinically important prognostic ...
Nicholas J Taylor +16 more
doaj +1 more source
Podarcis siculus latastei (Bedriaga, 1879) of the western pontine islands (italy) raised to the species rank, and a brief taxonomic overview of podarcis lizards [PDF]
, 2019 In recent years, great attention has been paid to many Podarcis species for which the observed intra-specific variability often revealed species complexes still characterized by an unresolved relationship. When compared to other species, P.
Bohme, W. +3 more
core +1 more source