MC1R and PTCH Gene Polymorphism in French Patients with Basal Cell Carcinomas [PDF]
Journal of Investigative Dermatology, 2006 In this study, we assessed the role of melanocortin 1 receptor (MC1R) variants and of two patched (PTCH) polymorphisms (c.3944C>T (P1315L), insertion 18 bp IVS1-83) as risk factors for basal cell carcinoma (BCC) in the French population. The population investigated comprised 126 BCC patients who were enrolled on the basis of specific criteria (multiple
Liboutet, Muriel +12 more
openaire +2 more sources
Effect of the MC1R gene on sexual dimorphism in melanin-based colorations. [PDF]
, 2015 Variants of the melanocortin-1 receptor (MC1R) gene result in abrupt, naturally selected colour morphs. These genetic variants may differentially affect sexual dimorphism if one morph is naturally selected in the two sexes but another morph is naturally ...
Béziers, P. +6 more
core +1 more source
Mutations in MC1R Gene Determine Black Coat Color Phenotype in Chinese Sheep [PDF]
The Scientific World Journal, 2013 The melanocortin receptor 1 (MC1R) plays a central role in regulation of animal coat color formation. In this study, we sequenced the complete coding region and parts of the 5′‐ and 3′‐untranslated regions of the MC1R gene in Chinese sheep with completely white (Large‐tailed Han sheep), black (Minxian Black‐fur sheep), and brown coat colors ...
Guang-Li Yang +6 more
openaire +3 more sources
Identification of key genes and evaluation of immune cell infiltration in vitiligo
Mathematical Biosciences and Engineering, 2021 Background: To improve the understanding of the molecular mechanism of vitiligo is necessary to predict and formulate new targeted gene therapy strategies.
Xiangyue Zhang +4 more
doaj +1 more source
Nuclear gene indicates coat-color polymorphism in mammoths [PDF]
, 2006 By amplifying the melanocortin type 1 receptor from the woolly mammoth, we can report the complete nucleotide sequence of a nuclear-encoded gene from an extinct species.
Bertranpetit, Jaume +8 more
core +1 more source
The Journal of Poultry Science, 2019 The Japanese quail expresses polymorphism in plumage colors, including black, yellow, white, wild-type (maroon), and various intermediate colors through hybridization of quail with different plumage colors.
Yi-xin Li +4 more
doaj +1 more source
Detection of Snps in the Melanocortin 1-Receptor (MC1R) and Its Association with Shank Color Trait in Hs Chicken [PDF]
Brazilian Journal of Poultry Science, 2019 The melanocortin 1 receptor (MC1R) gene plays a key role in controlling the deposition of melanin. In mammals, the MC1Rgene is regarded as a major candidate gene in the control of melanin formation.
X Shen +13 more
doaj +1 more source
Diversity across major and candidate genes in European local pig breeds [PDF]
, 2018 The aim of this work was to analyse the distribution of causal and candidate mutations associated to relevant productive traits in twenty local European pig breeds.
Alves, E. +28 more
core +1 more source
Identification of MC1R SNPs and their Association with Plumage Colors in Asian Duck
The Journal of Poultry Science, 2017 The melanocortin 1 receptor (MC1R) gene is a candidate functional gene that controls the pigment production in melanocytes. The aim of this study was to identify polymorphisms and investigate the effect of the MC1R gene on plumage coloration in duck ...
Hasina Sultana +8 more
doaj +1 more source
Genetics of skin color variation in Europeans: genome-wide association studies with functional follow-up [PDF]
, 2015 In the International Visible Trait Genetics (VisiGen) Consortium, we investigated the genetics of human skin color by combining a series of genome-wide association studies (GWAS) in a total of 17,262 Europeans with functional follow-up of discovered loci.
Bataille, V. (Veronique) +25 more
core +1 more source