Results 61 to 70 of about 12,611 (227)

ISOLASI DAN AMPLIFIKASI GEN PARSIAL MELANOCORTIN - 1 RECEPTOR (MC1R) PADA IKAN GURAME [PDF]

, 2015
Ikan Gurame (Osphronemus goramy) merupakan ikan air tawar yang banyak ditemukan di kawasan Indonesia yang memiliki kelimpahan yang cukup banyak serta memiliki banyak manfaat pada bidang pangan dan ekonomi. Potensi yang dimiliki dari O.
Indrawan, Nilamsari Kurniasih
core  

In Vitro Behavior and UV response of melanocytes derived from carriers of CDKN2A mutations and MC1R variants. [PDF]

, 2019
Co-inheritance of germline mutation in cyclin-dependent kinase inhibitor 2A (CDKN2A) and loss-of-function (LOF) melanocortin 1 receptor (MC1R) variants is clinically associated with exaggerated risk for melanoma.
Abdel-Malek, ZA, Anwar, A, Bennett, DC, Cassidy, P, Choi, K, Guard, S, Hernando, B, Kadekaro, AL, Leachman, S, Starner, RJ, Swope, VB   +10 more
core   +2 more sources

Pleiotropic effects of the melanocortin 1 receptor (MC1R) gene on human pigmentation [PDF]

Human Molecular Genetics, 2000
Variants of the melanocortin 1 receptor (MC1R) gene are common in individuals with red hair and fair skin, but the relative contribution to these pigmentary traits in heterozygotes, homozygotes and compound heterozygotes for variants at this locus from the multiple alleles present in Caucasian populations is unclear.
Flanagan, Niamh, Healy, Eugene, Ray, Amanda, Philips, Sion, Todd, Carole, Jackson, Ian J., Birch-Machin, Mark A., Rees, Jonathan L.   +7 more
openaire   +4 more sources

Harnessing blue light photobiomodulation for cancer therapy: Evidence from a systematic review

Photochemistry and Photobiology, EarlyView.
Conventional treatments for various types of cancer are often associated with tumor recurrence and aggressiveness. Photobiomodulation with blue light (BL; 450–470 nm) emerges as a promising alternative with antitumor effects. This systematic review, with 37 in vitro and in vivo studies from 2002 to 2024, revealed that BL reduces cell viability ...
Bárbara Evelyn Santos de Lima, Rebeca Barros Nascimento, Ana Paula Mariano Santos Ginez, Maria Stella Moreira, Rebeca Boltes Cecatto, Rodrigo Labat Marcos, Maria Fernanda Setúbal Destro Rodrigues   +6 more
wiley   +1 more source

Functional Characterization of MC1R-TUBB3 Intergenic Splice Variants of the Human Melanocortin 1 Receptor.

PLoS ONE, 2015
The melanocortin 1 receptor gene (MC1R) expressed in melanocytes is a major determinant of skin pigmentation. It encodes a Gs protein-coupled receptor activated by α-melanocyte stimulating hormone (αMSH).
Cecilia Herraiz, Conchi Olivares, Maria Castejón-Griñán, Marta Abrisqueta, Celia Jiménez-Cervantes, José Carlos García-Borrón   +5 more
doaj   +1 more source

Análisis de la asociación entre sexo y diferencias en pigmentación humana según el genotipo del gen MC1R [PDF]

, 2016
Introducción: La pigmentación cutánea basal y la respuesta al sol por bronceamiento son rasgos hereditarios influidos por varios genes, entre los que el gen mc1r es uno de los más importantes.
Hernando, Barbara, Ibarrola-Villava, Maider, Llorca-Cardeñosa, Marta J., Martinez-Cadenas, Conrado, Ribas, Gloria   +4 more
core   +1 more source

Rare Germline Variants in CDKN2A‐Negative Children and Adolescents With Cutaneous Melanoma

Pigment Cell &Melanoma Research, Volume 39, Issue 2, March 2026.
Individuals with childhood and adolescent melanoma carry inherited mutations in shelterin complex genes, pigmentation genes and MBD4, but have fewer MC1R R‐alleles than adults with melanoma. Created with BioRender.com. ABSTRACT Cutaneous melanoma is a complex disease influenced by both environmental and genetic factors. Inherited susceptibility plays a
Peter A. Johansson, Jane M. Palmer, Linh T. Bui‐Raborn, Mai Xu, Kristine M. Jones, Herbert Higson, Jia Liu, Kelly M. Brooks, Antonia L. Pritchard, Nicholas K. Hayward, Kevin M. Brown   +10 more
wiley   +1 more source

Distinct pigmentary and melanocortin 1 receptor-dependent components of cutaneous defense against ultraviolet radiation. [PDF]

PLoS Genetics, 2007
Genetic variation at the melanocortin 1 receptor (MC1R) is an important risk factor for developing ultraviolet (UV) radiation-induced skin cancer, the most common form of cancer in humans.
Craig S April, Gregory S Barsh
doaj   +1 more source

Genome-wide screening of mouse knockouts reveals novel genes required for normal integumentary and oculocutaneous structure and function. [PDF]

, 2019
Oculocutaneous syndromes are often due to mutations in single genes. In some cases, mouse models for these diseases exist in spontaneously occurring mutations, or in mice resulting from forward mutatagenesis screens.
Adissu, Hibret, Berberovic, Zorana, Clary, Dave, Eskandarian, Mohammad, Flenniken, Ann M, International Mouse Phenotyping Consortium, Lloyd, KC Kent, McKerlie, Colin, Moore, Bret A, Moshiri, Ala, Moshiri, Ata S, Murphy, Christopher J, Newbigging, Susan, Nutter, Lauryl MJ, Owen, Celeste, Thomasy, Sara M   +15 more
core  

Assessment of MC1R and α-MSH gene sequences in Iranian vitiligo patients

Indian Journal of Dermatology, 2010
Vitiligo is an acquired pigmentary disorder of the skin that is caused by unknown factors and is characterized by white and depigmented patches that enlarge and become more numerous with time. Genetic factors, oxidative stress, autoimmunity, and neurochemical agents, such as catecholamines might also contribute to vitiligo.
Eskandani, M, Hasannia, S, Vandghanooni, S, Pirooznia, N, Golchai, J   +4 more
openaire   +2 more sources