Results 151 to 160 of about 10,319 (179)

G protein–independent MC4R signaling

Science Signaling, 2015
MC4R controls appetite by modulating potassium channel activity.
openaire   +1 more source

?????????? Asp298Asn ???????????????????????? ???????? mc4r ?? ???????????????? ???????????????? ???????? ?? ???????????? ?????????????? ?????????? ????????????

2014
?????????????????????? ?????????? Asp298Asn-???????????????????????? ???????? mc4r c ?????????????????? ???????????? ????????????????, ?????? ?????????????? ???????????????? ???????? ?? ???????????? ?????????????? ?????????? ???????????? ?????????????????? ???? ????????????????????. ???????????????????? ?????????????????? ???????????????????????? ??????
openaire   +1 more source

Melanocortin 4 Receptor (MC4R) Deficiency

2018
An 18-year-old female student comes for an evaluation, accompanied by her parents. She has been considering bariatric surgery to manage her long-standing history of obesity. The patient reports that since early childhood, she has had “weight issues.” Her parents remember that at 12 months of age, she was always hungry and constantly seeking food.
openaire   +1 more source

POMC/MC4R signaling in Alzheimer's disease

2019
Alzheimer’s disease (AD) is the most prevalent form of dementia worldwide. It is characterized by synaptic deficits, excessive β-amyloid (Aβ) accumulation, and hyperphosphorylation of intraneuronal tau protein in brain. However, the mechanisms underlying AD pathology is unclear, and no effective treatment has been developed.
openaire   +2 more sources

Link between MC4R mutations and adiposity

Nature Reviews Endocrinology, 2021
openaire   +2 more sources

Evolutionary Perspective of MC4R

Aktuelle Ernährungsmedizin, 2006
DA Hughes, A Hinney, AK Wermter, J Hebebrand, H Biebermann, M Stoneking   +5 more
openaire   +1 more source

A SNP in the cattle MC4R gene is used to map MC4R to BTA 24

Animal Genetics, 2001
T D, Thue, S M, Schmutz, F C, Buchanan
openaire   +2 more sources

Structural analysis of setmelanotide binding to MC4R variants in comparison to wild-type receptor

Life Sciences, 2022
Fahd Al-Mulla, Anwar Mohammad, Mohamed Abu-Farha   +2 more
exaly  

The interaction between the dietary inflammatory index and MC4R gene variants on cardiovascular risk factors

Clinical Nutrition, 2021
, Cain C T Clark, Habib Yarizadeh
exaly  

MC4R biased signalling and the conformational basis of biological function selections

Journal of Cellular and Molecular Medicine, 2022
Zekun Liu, VÍCTOR Hruby
exaly